1983
DOI: 10.1016/0091-6749(83)90441-4
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Comparison of antigenic and allergenic composition of two partially puriflied extracts from and mite cultures

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Cited by 43 publications
(13 citation statements)
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“…In the particular case of D. farinae, previous results [11] have shown that mite-sensitive patients presented an individual pattern of IgE specificities in their se rum. The frequent occurrence of IgE versus 2 major allergens, Df 6 and Df 11, was also noted.…”
Section: Discussionmentioning
confidence: 96%
See 1 more Smart Citation
“…In the particular case of D. farinae, previous results [11] have shown that mite-sensitive patients presented an individual pattern of IgE specificities in their se rum. The frequent occurrence of IgE versus 2 major allergens, Df 6 and Df 11, was also noted.…”
Section: Discussionmentioning
confidence: 96%
“…Thus, studying the IgE response towards D. farinae extract in sera of patients sensitive to this mite, it has been shown that two allergens, Df 6 and Df 11, can be characterized as major allergens in Dermatophagoides farinae mite [11]. Df 6 and Df 11 have been purified and they are available to investigate the IgE response towards these allergens in D. farinae-sensitive pa tients.…”
Section: Introductionmentioning
confidence: 99%
“…Attempting to apply the RIA for antigen Pi to assay dust from North America, we had problems because many houses contained D. farinae either alone or as well as D. pteronyssinus. Although the two mites are known to cross-react [10], D. farinae extracts will only partially inhibit the RI A for antigen Pi so that quantitative results could not be obtained for dust samples containing D.farinae [ 11].…”
mentioning
confidence: 99%
“…The eluted antibody showed complete cross-reactivity between antigen Pi and the equivalent allergen from D. farinae, antigen F|. (Antigen F] is the same as Agl 1, identified by Dr. Dandeau [10].) Using this purified antibody, rabbitanti-Pi equivalent, we developed a radioimmunoas say for the cross-reacting determinants, or antigen Pi equivalent [11].…”
mentioning
confidence: 99%
“…On im munodiffusion and crossed radioimmunoelectrophoresis using polyclonal rabbit antisera [3,4], ex tracts of both mite cultures also appear to contain spe cies-specific antigens/allergens. Surprisingly, al though major allergens have been purified from each species, the antigenic interrelationships between them have not been clearly defined.…”
mentioning
confidence: 99%