Comparison of antimicrobial prescribing between two specialist paediatric centres in the UK and Latvia

Sviestiņa, Inese; Aston, Jeff; Mozgis, Dzintars

doi:10.1136/ejhpharm-2012-000179

Cited by 4 publications

(6 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This could be part of an ASPs to be developed at a national level, and could also be part of the national action plan of Pakistan for AMR [64]. The UK, for example, has successfully managed to reduce the use of the third-generation cephalosporins by introducing antimicrobial stewardship programs [65,66], providing guidance to others. In addition, a lower proportion of broad-spectrum antibiotics indicates better practice [67].…”

Section: Discussionmentioning

confidence: 99%

A multicenter point prevalence survey of antibiotic use in Punjab, Pakistan: findings and implications

Saleem

Hassali

Versporten

et al. 2019

Expert Review of Anti-infective Therapy

View full text Add to dashboard Cite

Objective:In line with the recent global action plan for antimicrobial resistance, the first time such a comprehensive survey has been undertaken in Pakistan, sixth most populous country. Method:This point prevalence survey (PPS) was conducted in 13 hospitals among 7 different cities of Pakistan. The survey included all inpatients receiving an antibiotic on the day of PPS. A web-based application was used for data entry, validation, and reporting as designed by the University of Antwerp. Results:Out of 1954 patients, 1516 (77.6%) were treated with antibiotics. Top three most reported indications for antibiotic use were prophylaxis for obstetrics or gynaecological indications (16.5%) and gastrointestinal indications (12.6%) and lower respiratory tract infections (12.0%). Top three most commonly prescribed antibiotics were ceftriaxone (35.0%), metronidazole (16.0%) and ciprofloxacin (6.0%). Out of total indications, 34.2% of antibiotics were prescribed for community-acquired infections (CAI), 5.9% for healthcare-associated infections (HAI), and 57.4% for either surgical or medical prophylaxis. Of total surgical prophylaxis, 97.4% of antibiotics were given for more than one day. Conclusion:Study concluded that unnecessary prophylactic antibiotic use is extremely high and broad-spectrum prescribing is common. There is a considerable need to work on a national action plan of Pakistan on antibiotic resistance.

show abstract

Section: Discussionmentioning

confidence: 99%

A multicenter point prevalence survey of antibiotic use in Punjab, Pakistan: findings and implications

Saleem

Hassali

Versporten

et al. 2019

Expert Review of Anti-infective Therapy

View full text Add to dashboard Cite

show abstract

“…Some European countries have reported high increase of the third-generation cephalosporin-resistant Escherichia coli in their hospital wards [19]. At the same time some countries such as UK have succeeded in decreasing of the use of the third-generation cephalosporins with both publications from the Department of Health recommending good antimicrobial stewardship, e.g., the ''Start Smart then Focus'' approach [20] and a policy of restricting cephalosporin prescription and this approach helped to decrease the use of cephalosporins, for example, in the Children Hospital in Birmingham [21]. Currently there are almost no local and also national recommendations for antibiotic use in hospitals except one University Hospital with a maternity ward that has local recommendations for adults and the University Childrens' Hospital that has local recommendations for bronchiolitis, epiglottitis, croup and community acquired pneumonia treatment.…”

Section: Discussionmentioning

confidence: 99%

Antimicrobial usage among hospitalized children in Latvia: A neonatal and pediatric antimicrobial point prevalence survey

Sviestiņa

Mozgis

2014

Medicina

Self Cite

View full text Add to dashboard Cite

show abstract

“…The results of drug expenditure from our research are classified as rational expenditure comparing with drug expenditure in other countries in transitional phase [ 8 – 10 ].…”

Section: Discussionmentioning

confidence: 99%

“…In Department of Pulmonology of Pediatric Clinic, the most utilised antibiotic was Procaine penicillin. Sestina et al [ 10 ] showed that in hospitalised paediatric patients in Birmingham the most frequently used antibiotic was co-amoxiclav while in Riga ampicillin and amoxicillin were most commonly used. This difference in practice is interesting as in most cases these narrow-spectrum agents provide sufficient cover for the majority of pathogens associated with community acquired pneumonia.…”

Section: Discussionmentioning

confidence: 99%

Antibiotic Utilization in Pediatric Hospitalized Patients â€“ A Single Center Study

Bytyqi¹,

Hoxha²,

Bahtiri³

et al. 2017

Open Access Maced J Med Sci

View full text Add to dashboard Cite

BACKGROUND:Antibiotics are among the most commonly prescribed drugs in paediatrics. In most cases, antibiotics are started on an empirical basis, without proof of a bacterial infection, either before the start of therapy or afterwards.AIM:The main objective of this study was to analyse the consumption of antibiotics in hospitalised paediatric patients.MATERIAL AND METHODS:This retrospective study investigated the consumption of antimicrobials in defined daily doses (DDDs according to the Anatomical Therapeutical Chemical/DDD index) in Pulmonology, Gastroenterology and Nephrology Departments at Pediatric Clinic of the tertiary hospital. The data on the consumption of antimicrobials were collected for five years by using properly designed form. The consumption was related to days of hospital care.RESULTS:The most utilised antibiotics group in all three departments Pulmonology, Gastroenterology and Nephrology Departments were penicillins. Cephalosporins were mostly used in Pulmonology department. Metronidazole and Chloramphenicol were used in minimal quantities in all three departments.CONCLUSION:This study demonstrates that surveillance programs on antibiotic resistance should be established and accompanied by analyses of drug utilisation data which can aid in the creation of valid cross-national studies on antibiotic usage and resistance, to motivate improvements in prescribing and guideline-directed antibiotic prescribing.

show abstract

Comparison of antimicrobial prescribing between two specialist paediatric centres in the UK and Latvia

Cited by 4 publications

References 21 publications

A multicenter point prevalence survey of antibiotic use in Punjab, Pakistan: findings and implications

A multicenter point prevalence survey of antibiotic use in Punjab, Pakistan: findings and implications

Antimicrobial usage among hospitalized children in Latvia: A neonatal and pediatric antimicrobial point prevalence survey

Antibiotic Utilization in Pediatric Hospitalized Patients â€“ A Single Center Study

Contact Info

Product

Resources

About