Comparison of Antioxidant and Anticholinesterase Activities of Selected Pleurotus Species (Agaricomycetes) from India

Randhawa, Kudrat; Shri, Richa

doi:10.1615/intjmedmushrooms.2018027033

Cited by 5 publications

(2 citation statements)

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“…The latter reacts with 5, 5'-dithiobis (2-nitrobenzoic acid) (DTNB), thereby producing 2-nitrobenzoate-5mercaptothiocholine and %-thio-2-nitrobenzoate, which can be detected at 412 nm. All the readings were taken in triplicate 11,45,46 .…”

Section: In-vitro Acetylcholinesterase (Ache) Inhibitory Activitymentioning

confidence: 99%

Untitled

2022

IJPSR

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Environmental factors influence plant growth, morphology, as well as nature and quantity of secondary metabolites. Modification of abiotic factors during plant growth can impact the production of bioactive phytoconstituents. A six-month field study was carried out to assess the effect of different abiotic stresses on bioactive compounds (flavonoids, phenols, quercetin), acetylcholine sterase (AChE) inhibition and antioxidant capacity of two selected Allium species i.e. Allium cepa L. (AC) & Allium sativum L. (AS; family Amaryllidaceae). AC and AS plants were grown for six months (from November 2018 to April 2019) on three different soil types (i.e. black, red, clay-loamy) and various stresses (salinity, water deprivation, flooding, fertilizer, metal, shade) were applied on the plants. At the end of the season, plants were collected, dried and plant yield was determined. Hydro alcoholic extracts of all samples were prepared. Extract yield, total flavonoids (TFC), total phenols (TPC), AChE inhibition, and antioxidant activity were determined in all the extracts. The results show the varied response of AC & AS plants to different soil types and stresses. AS plants grown in red soil with salt stress and AC plants on red soil with fertilization give higher biomass yield. AC plants grown in black soil and AS in red soil under metal stress have the highest TFC, TPC, AChE inhibition, and antioxidant activity. Hence these conditions may be recommended for incorporation in cultivation practices of these valuable medicinal plants. This would ensure a commercial supply of plants with higher phenol and flavonoid content and better activity. INTRODUCTION: Onions Allium cepa L. (AC) and garlic Allium sativum L. (AS) are highly valued members of the genus Allium (Family Amaryllidaceae) 1 . AC and AS are considered imperative dietary components due to their unique QUICK RESPONSE CODE

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Section: In-vitro Acetylcholinesterase (Ache) Inhibitory Activitymentioning

confidence: 99%

Untitled

2022

IJPSR

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“…The mushrooms are used effectively in the treatment or prevention of many diseases by extracting the active substances in their compositions because of their nutritional and medicinal properties. There are many species of edible mushrooms that have been found to have antitumor, cardiovascular, antimicrobial and immunoregulatory properties (Randhawa and Shri, 2018;Su et al, 2019). The effects of the mushrooms, especially on the immune system, have increased their importance in recent years.…”

Section: Introductionmentioning

confidence: 99%

Suillus collinitus (Fr.) Kuntze ekstraktlarının insan lenfositlerinin genotoksisitesi ve proliferasyonu üzerindeki etkileri

Emsen

Türel

Uzun

2019

Anatolian Journal of Botany

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Cultivated or wild edible mushroom species have traditionally been used by humans for medical purposes for many years. Edible mushrooms have the potential to show different activities due to the numerous bioactive components they contain. In particular, some mushroom species whose regulatory properties have been identified on human immunity are of interest in the scientific world. Considering these characteristics of edible mushroom species, in the present study, it was examined the effects of Suillus collinitus (Fr.) Kuntze, an important edible mushroom species, on human peripheral lymphocytes. For this purpose, acetone and water extracts were obtained from S. collinitus and the effects of these extracts on genotoxicity and proliferation of human lymphocytes were tested by chromosome aberration (CA), micronucleus (MN), nuclear division index (NBI) and mitotic index (MI) analyses. When genotoxicity analyses were examined, it was found that none of the tested extract applications (1-100 mg/L) did not change the CA and MN frequencies statistically (p > 0.05) compared to the negative control group. Proliferation analyses showed that only the maximum concentration (100 mg/L) application of acetone extract of S. collinitus decreased the NBI and MI ratio of the cells at a level of p < 0.05 compared to the negative control group. The obtained results revealed that the acetone and water extracts of S. collinitus, especially the applications at concentrations of 1-50 mg/L, did not show any genotoxic or cytotoxic activity on lymphocytes involved in the human immune system.

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