Comparison of Antioxidant and Antimicrobial Properties for Ginkgo biloba and Rosemary (Rosmarinus officinalis L.) from Egypt

Abstract

The widespread use of medicinal plants for health purposes has increased dramatically due to their great importance to the public health. In this study levels of phenolic, flavonoid contents of Ginkgo biloba and Rosmarinus officinalis from Egypt were determined. HPLC was used to identify and quantify the phenolic compounds in selected plants. The plant extracts were evaluated for their antioxidant activities using various antioxidant methodologies, (i) scavenging of free radicals using 2, 2-diphenyl-1-picrylhydrazyl, (ii) metal ion chelating capacity, and (iii) scavenging of superoxide anion radical. The antimicrobial activity of both plant's extracts were evaluated against a panel of microorganisms by using agar disc diffusion method. The total phenolic content (75.30 and 98.31 mg/g dry weight in G. biloba and R. officinalis, respectively) was significantly (p<0.05) different. Among the identified phenolic compounds, quercetin, kaempferol and caffeic acid were the predominant phenolic compounds in Ginkgo biloba, whereas carnosic acid, rosmarinic acid, narinigen and hispidulin were the predominant phenolic compound in Rosmarinus officinalis leaves. The antioxidant activity increased with the concentration increase. The R. officinalis was more active than G. biloba extract against Gram-negative bacteria. This study reveals that the consumption of these plants would exert several beneficial effects by virtue of their antioxidant and antimicrobial activities.

Protective effect of rosemary on acrylamide motor neurotoxicity in spinal cord of rat offspring: postnatal follow-up study

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Biological Activities of the Doum Palm (Hyphaene thebaica L.) Extract and Its Bioactive Components

“…The oxidative stress is defined as the imbalance between oxidants and antioxidants in favor of the oxidants potentially leading to damage in human cells. Physiologically, antioxidants play a major role in preventing the formation of free radicals, which are responsible for many harmful oxidative processes [50]. Antioxidants may be synthetic or of natural source [51].…”

Assessment the Protective Role of Quercetin on Acrylamide-Induced Oxidative Stress in Rats

“…Thus, it is especially important for the intervention against acrylamide toxicity to explore the bioactive compounds that can effectively ameliorate oxidative stress. Quercetin is one of the most frequently studied dietary flavonoids, distributed in vegetables, fruits and many other dietary sources (Bhatt and Flora 2009;El-Beltagi and Badawi 2013). Quercetin possesses various biological functions including, anti-inflammatory, anti-coagulation, oxygen radical-scavenging activities (Yu et al 2013).…”