Comparison of Bedside- and Laboratory-Inoculated Bactec High- and Low-Volume Resin Bottles for the Recovery of Microorganisms Causing Peritonitis in CAPD Patients

Consensus Guidelines for the Prevention and Treatment of Catheter-Related Infections and Peritonitis in Pediatric Patients Receiving Peritoneal Dialysis: 2012 Update

“…Rapid blood culture techniques such as Bactec (Becton–Dickinson, Franklin Lakes, NJ, USA), Septi-Chek (Becton–Dickinson), and BacT/Alert (bioMérieux, Marcy l'Etoile, France) are useful in reducing the time to identification of the micro-organism causing the peritonitis. Bedside-inoculated bottles have not been shown to be significantly better than laboratory-inoculated bottles, and high-volume bottles were not significantly better than low-volume bottles for the detection of patients positive for micro-organisms; however, the total number of micro-organisms recovered was significantly better from inoculated blood culture bottles than from routine culture (166). Two recent prospective studies also support the routine use of the broth culture technique compared with the water lysis technique (167,168).…”

Blood culture bottles are superior to conventional media for vitreous culture

“…This variable yield rate was attributed to the limited amounts of the vitreous specimens. There were many reports of an increased positive culture rate in other fluid specimens such as peritoneal fluid, pleural fluid, joint fluid and pancreatic pseudocyst by using blood culture bottles (BCB). Previous studies also demonstrated that vitreous fluid cultures with BCB were superior to conventional media with statistically significant differences .…”

Performance of the BacT/Alert Virtuo Microbial Detection System for the culture of sterile body fluids: prospective multicentre study

“…Direct Gram stain results and quantity of growth help determine the clinical significance of culture results. Inoculation of blood culture bottles with SBF specimens in the laboratory, rather than at the bedside, has been shown to not significantly affect pathogen recovery in cases of CAPD-associated peritonitis [5]. In the current study, all inoculations were performed after receipt of the specimen by laboratory personnel.…”