Comparison of Broiler Performance and Carcass Yields When Fed Diets Containing Transgenic Maize Grains from Event DP-Ø9814Ø-6 (Optimum GAT), Near-Isogenic Control Maize Grain, or Commercial Reference Maize Grains

Abstract

A genetically modified maize (Zea mays L.) line that contains the Optimum GAT trait (event DP-Ø9814Ø-6; 98140) was produced by integration of the gat4621 and zm-hra genes. The expressed GAT4621 and ZM-HRA proteins confer tolerance to the herbicidal active ingredient glyphosate and acetolactate synthase-inhibiting herbicides, respectively. The objective of this study was to compare the nutritional performance of 98140 maize grain to nontransgenic maize grain in a 42-d feeding trial in broiler chickens. Diets were prepared using grain from untreated 98140 plants and from plants treated with an in-field application of herbicides (98140 + Spray). For comparison, additional diets were produced with maize grain obtained from the nontransgenic near-isogenic control (control) and nontransgenic commercial reference Pioneer brand hybrids 33J56, 33P66, and 33R77. Diets were fed to Ross x Cobb broilers (n = 120/group, 50% male and 50% female) in 3 phases: starter, grower, and finisher containing 58.5, 64, and 71.5% maize grain, respectively. No statistically significant differences were observed in mortality, growth performance variables, or carcass and organ yields between broilers consuming diets produced with maize grains from unsprayed or sprayed 98140 and those consuming diets produced with near-isogenic control maize grain. Additionally, all performance and carcass variables from control, 98140, and 98140 + Spray test maize treatment groups were within tolerance intervals constructed using data from reference maize groups. Based on these results, it was concluded that 98140 maize grain (unsprayed or sprayed with a herbicide mixture) was nutritionally equivalent to nontransgenic control maize with comparable genetic background.

Effect of Dietary Phytase Transgenic Corn on Physiological Characteristics and the Fate of Recombinant Plant DNA in Laying Hens

“…This finding is consistent with those of previous studies in which no biologically significant differences in organ indices (McNaughton et al, 2008) or serum biochemical parameters (Appenzeller et al, 2009) were observed between animals fed diets prepared with GM or non-GM grain. This suggests that a diet prepared from PTC has no unintended effects on serum biochemical parameters and organ weight as compared to a CC-based diet.…”

Detection of Transgenic and Endogenous Plant DNA Fragments and Proteins in the Digesta, Blood, Tissues, and Eggs of Laying Hens Fed with Phytase Transgenic Corn

“…This finding agrees with the results of previous studies that have confirmed laying hen performance is not affected by GM plants as compared to their conventional counterpart [26], [27]. Comparative studies [28], [29] with broilers fed GM maize and its isogenic non-GM varieties also showed that there were no adverse effects on the growth performance parameters. Likewise, no significant difference in growth performance parameters of pigs [30], steers [31], cows [32], fishes [33], or rats [34] receiving a non-GM diet or a GM plant-based diet has also been reported.…”

Evaluation of the safety and nutritional equivalency of maize grain with genetically modified event DP-Ø23211-2

“…Other researchers have similarly reported a lack of diet-related or biologically significant differences in growth performance, organ yields, and carcass or individual parts yields between broilers fed diets formulated with GM maize grains and broilers fed diets formulated with non-GM near-isogenic control maize grains. 6,[60][61][62][63][64][65] The observed lack of effects in this study demonstrates that DP23211 maize grain is as safe and nutritious as maize grain not containing event DP-Ø23211-2.…”