2013
DOI: 10.4103/0259-1162.123248
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Comparison of colloid preload versus coload under low dose spinal anesthesia for cesarean delivery

Abstract: Background:Although fluid bolus is considered as a conventional prophylactic measure to prevent spinal-induced hypotension; vasopressors are nevertheless required. Low dose spinal anesthetics could markedly reduce such episodes of hypotension, by minimizing sympathetic blockade.Aims:We chose to compare the relative efficacy of colloid preload versus coload under low dose spinal anesthesia, for elective cesarean delivery.Settings and Design:A prospective, randomized, double-blinded study.Materials and Methods:I… Show more

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Cited by 12 publications
(28 citation statements)
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“…The capillary hydraulic pressure increases over time during crystalloid infusion, which may lead to increased hydraulic pressure difference and fluid filtration from plasma into Interstitium. Timing of crystalloid infusion plays the crucial role as it gets distributed across extracellular space into interstitial space leading to suboptimal intravascular expansion [9,10,11] . Pouta et al described role of increased atrial natriuretic peptide [16] .…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…The capillary hydraulic pressure increases over time during crystalloid infusion, which may lead to increased hydraulic pressure difference and fluid filtration from plasma into Interstitium. Timing of crystalloid infusion plays the crucial role as it gets distributed across extracellular space into interstitial space leading to suboptimal intravascular expansion [9,10,11] . Pouta et al described role of increased atrial natriuretic peptide [16] .…”
Section: Discussionmentioning
confidence: 99%
“…So, trials were conducted to assess the effectiveness of co-loading i.e. rapid fluid administration at the time of giving spinal anaesthesia [9,10,11] . This approach may limit fluid redistribution and prevent hypotension.…”
Section: Introductionmentioning
confidence: 99%
“…In three trials, [17,18,20] the infusion volume of intervention groups was set as 15 mL/kg colloid preload, two [22,24] as 10 mL/kg, and the other four as [19,21,23,25] 500 mL. As for the control groups, the infusion methods were set as 15 mL/kg colloid coload in two trials, [18,20] 10 mL/kg colloid coload in two trials, [22,24] 500 mL colloid coload in two trials, [19,21] and 1000 mL crystalloid coload in two trials. [23,25] Another trial did not specify the amount of crystalloid coload in the control group.…”
Section: Study Selection and Characteristicsmentioning
confidence: 99%
“…Data from seven studies [17][18][19][20][21][22][23] showed that the umbilical arterial pH was significantly lower in the colloid preload group (MD = À0.01, 95% CI À0.02 to À0.00, P = 0.04) [Figure 7].…”
Section: Umbilical Artery Phmentioning
confidence: 99%
“…Some studies showed that colloids may be more effective than crystalloids for preventing hypotension [ 8 , 9 ]. As for colloids, the preload group had lower incidence of hypotension than the coload group [ 10 ], but the administration of additional 0.5 L offered no added benefits [ 6 ]. However, there are several disadvantages associated with colloids, such as cost, allergic reactions, and their effects on coagulation.…”
Section: Introductionmentioning
confidence: 99%