Comparison of complications of total thyroidectomy in malignant vs. benign thyroid tumors

Iddings, D.; Walsh, Erika M.; Raiji, Manish T.; Ghanem, Muhammad; Rao, Vishal; Wiese, Dawn M.; Hammoud, Jamal; Bakleh, M.; Nelson, Jeremy

doi:10.1200/jco.2008.26.15_suppl.17012

Cited by 2 publications

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“…The rate of complications varies between patients with the malignant and benign disease based on the disease condition and management. The incidence rate of complications was high in patients with the malignant disease with 69.23% in the present study which is conflicting to the study result performed by Iddings D et al [9] in which majority of the patients had benign pathology with 68%. In a study conducted for the population size of 83, the complication rate for the malignant disease was 10% and 2% for benign diseases in Spear SA et al [7] study.…”

Section: Discussioncontrasting

confidence: 99%

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Profile and complication rate of thyroid surgeries performed in a tertiary care teaching hospital, a prospective observational study

Sathiah

Chandrabose

2019

Int J Surg Ortho

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Background: One of the most common endocrine disorder is the thyroid diseases. The prevalence and pattern of these conditions depends on sex, age, ethnic and geographic patterns. The incidence of thyroid nodules increases with the age hence benign and malignant thyroid disease is common in the elderly population. Aim: To compare the complication rate of various thyroid surgeries for benign and malignant diseases in a tertiary care teaching hospital. Methods: This study was a prospective observational study, Velammal medical college hospital at Tamil Nadu from December 2018-June 2019. The patients who underwent thyroid surgery for various thyroid disorders were enrolled in the study. Results: Out of117 cases, 107 were women and 10 were men. Multinodular goiter (MNG)was the most common (38.46%) condition, followed by solitary nodule (29.06%) and toxic MNG (18.8%). Among women, 40.19% were identified with multinodular goiter followed by solitary nodule (28.97%). Subtotal thyroidectomy was performed for 88.89% of MNGs, while 91.18% of the solitary nodule were managed by hemithyroidectomy Majority of the patients with toxic MNG underwent subtotal thyroidectomy with 99.91%. While 84.61% of the patients with thyroid cancer were treated by total thyroidectomy. The overall incidence of complications was 27.35%. The incidence rate of complications was high in patients with malignant disease, as compared to benign disease (69.23% in Malignant Vs 36.36% in toxic MNG and 24.44% in MNG). Conclusion: Through the present study, it was concluded that the complications associated with the different thyroid surgeries and various precautions that can be taken to reduce the complications.

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Section: Discussioncontrasting

confidence: 99%

“…Complications associated with total thyroidectomy can be reduced by performing surgeon's experience, monitoring and identifying patients at risk [9].…”

Section: Introductionmentioning

confidence: 99%

Profile and complication rate of thyroid surgeries performed in a tertiary care teaching hospital, a prospective observational study

Sathiah

Chandrabose

2019

Int J Surg Ortho

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“…It is increasingly recognized that TT is appropriate for surgical treatment of BMNG T+E particularly when both lobes are involved [16].…”

Section: Discussionmentioning

confidence: 99%

Evaluation of Total Thyroidectomy for Treatment of Benign Diseases of Thyroid Gland

Чоланчески

Tolevska

Qafjani

et al. 2020

Open Access Maced J Med Sci

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BACKGROUND: The controversy of using total thyroidectomy (TT) in treatment of benign thyroid diseases still remains controversial over the rates of complication, mostly recurrence nerve palsy and hypocalcemia, compared to non-total thyroidectomies. The latest reports in this field of research showed that that the number of complications of TT is decreasing as the skills of surgeons increase. AIM: In this study, we reviewed 209 cases of total thyroidectomies for benign thyroid diseases where such surgery was indicated. The results were evaluated whether they support the previous reports that TT is save method of treatment of diffuse multinodular goiters, Graves’ disease thyroid adenomas with diffuse goiters and thyroiditis. METHODS: Two hundred and nine patients, 36 males and 173 females, medium age 47 (17–77) operated with TT between 2016 and 2018 were included in the evaluation study. We evaluated the: Diagnosis, indications for operation, pre-operative medication administration, laryngeal recurrent nerve palsy, hypocalcemia, hypoparathyroidism, and patohistology findings. The follow-up for hypocalcemia and laryngeal nerve palsy was performed 1 year postoperatively. RESULTS: The age of the patients was between 17 and 77 years, medium-range 47 years old. Of 209 patients, 173 (83%) were female and 36 (17%) male with a gender ratio of 1:4.8 males to females. Diagnoses before surgery were established as follows: Multinodular euthyroid goiter (MNEG) n = 106 (48.80%), multinodular toxic goiter n = 12 (5.74%), Graves’s disease n = 6 (2.87%), adenoma with multinodular goiter n = 73 (34.92%), and n = 16 (7.65%) patients with thyroiditis. Recurrence laryngeal nerve palsy (RLNP) occurred in 6 patients (2.87%), temporary within 3 months after the operation in 4 patients (1.92%) and permanent palsy within 6 months and more after an operation in 2 patients (0.95%). Voice hoarseness immediately and within 1 month after the operation was registered in 32 patients (15.3%). RLNP and hoarseness were registered mostly in patients with pre-operative problems, mostly with extra big MNEG. One of the permanent injuries of RLN was bilateral and all others were one sided. All patients were operated with normal pre-operative vocal cord movement findings. Post-operative hypocalcemia was registered in 35 patients (16.74%). Temporary nonsignificant hypocalcemia in 10 (4.78%), temporary significant hypocalcemia in 17 (8.13%), temporary severe hypocalcemia in 6 patients (2.87%), and permanent hypocalcemia in 2 patients (0.95%). CONCLUSION: Many studies have shown that the rate of complications is almost even for TT and NTT done for benign and malignant diseases of thyroid gland. Our data have shown that the risk of post-operative complications with TT is proportional to the number of complicated pre-operative findings of benign thyroid glands.

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Comparison of complications of total thyroidectomy in malignant vs. benign thyroid tumors

Cited by 2 publications

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Profile and complication rate of thyroid surgeries performed in a tertiary care teaching hospital, a prospective observational study

Profile and complication rate of thyroid surgeries performed in a tertiary care teaching hospital, a prospective observational study

Evaluation of Total Thyroidectomy for Treatment of Benign Diseases of Thyroid Gland

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