Comparison of Conjunctival Autograft With Amniotic Membrane Transplantation for Pterygium Surgery

Küçükerdönmez, Cem; Akova, Yonca A.; Altınörs, Dilek Dursun

doi:10.1097/ico.0b013e318033b3d4

Cited by 78 publications

(35 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…However, Dadeya et al [11 ]did not find any significant difference in recurrence outcome with rotated autografts. Furthermore, as for the use of amniotic membrane as an alternative to CAGs, Küçükerdönmez et al [12] did not yield any significant difference in recurrence rates in a prospective randomized clinical trial of 78 patients, and both Tananuvat and Martin [13 ]and Liang et al [14] demonstrated lower recurrent rates while using CAGs. With CAGs including the limbal areas, Han et al [15] and Torres et al [16] reported recurrence rates of 1.9 and 7.9%, respectively.…”

Section: Discussionmentioning

confidence: 99%

Pterygium Recurrence, Astigmatism and Visual Acuity following Bare-Sclera Excision and Conjunctival Autograft with or without Additional Phototherapeutic Keratectomy

Promesberger¹,

Kohli²,

Busse³

et al. 2013

Ophthalmic Res

View full text Add to dashboard Cite

Background: Treatment outcome in patients with pterygium following bare-sclera excision and conjunctival autograft (CAG) with and without phototherapeutic keratectomy (PTK). Methods: Retrospective comparative analysis of 81 eyes, with primary and recurrent pterygia, that were analyzed for recurrence, best-corrected visual acuity (BCVA) and astigmatism in primary (P1 without PTK, P2 with PTK) and recurrent pterygia (R1 without PTK, R2 with PTK). BCVA and astigmatism were compared in patients with simple CAG alone (group I) or in combination with PTK (group II). Results: Recurrence rates were 4.7, 11.6, 16.2, 23.2 and 32.5% at 3, 6, 12, 24 and >24 months (P1), 7.1% at >24 months (P2). Recurrence rates were 5.3, 10.5, 21.1, 21.1 and 26.3% at 3, 6, 12, 24 and >24 months (R1) and 1 recurrence (7.7%) till month 24, and 3 (23.1%) thereafter (R2). BCVA increased from logarithm of the minimal angle of resolution 0.095 ± 0.141 (mean ± SD) at baseline to 0.066 ± 0.09 (group I), and from 0.090 ± 0.164 to 0.054 ± 0.124 (group II). Astigmatism decreased from -1.01 ± 0.90 dpt at baseline to -0.97 ± 1.24 dpt (group I), and from -1.19 ± 1.55 to -0.75 ± 0.87 dpt (group II). Conclusion: In comparison to CAG alone, additional excimer smoothing with PTK tends to increase BCVA and reduces recurrence rates in patients with primary pterygia.

show abstract

Section: Discussionmentioning

confidence: 99%

Pterygium Recurrence, Astigmatism and Visual Acuity following Bare-Sclera Excision and Conjunctival Autograft with or without Additional Phototherapeutic Keratectomy

Promesberger¹,

Kohli²,

Busse³

et al. 2013

Ophthalmic Res

View full text Add to dashboard Cite

show abstract

“…Theoretically, limbal autografts can restore the barrier function against conjunctival invasion to the cornea by facilitating healthy epithelialization as well as by reconstructing the limbal structure [17,19,22,23]. Clinically, many studies have previously demonstrated a significantly lower recurrence rate after limbal-conjunctival autograft surgery than after other procedures, including AM transplantation, MMC application, and the bare-sclera method [1,4,6,11,17]. Limbal-conjunctival grafting was also demonstrated to be superior to conventional conjunctival grafting in lowering the recurrence rate in advanced and recurrent pterygia [11].…”

Section: Discussionmentioning

confidence: 99%

“…This condition causes cosmetic problems and occasional visual disturbance, and successful surgical treatment continues to be a challenge due to a high recurrence rate, especially in patients treated with the bare-sclera technique [1,2,3,4]. …”

Section: Introductionmentioning

confidence: 99%

“…Surgical options have been developed, such as conjunctival autograft, limbal and limbal-conjunctival autograft, conjunctival flap and conjunctival rotation autograft, amniotic membrane (AM) transplantations, lamellar keratoplasty, and use of fibrin glue [1,2,4,6,7,8,9,10,11,12]. In particular, with the advanced understanding of the importance of limbal stem cells in the pathogenesis of pterygium [7,13,14,15], limbal graft transplantation has gained popularity as a method of diminishing recurrences by facilitating the recovery of the limbal barrier function [10,12,16,17].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Efficacy and Safety of Limbal-Conjunctival Autografting with Limbal Fixation Sutures after Pterygium Excision

et al. 2012

View full text Add to dashboard Cite

Purpose: To evaluate the efficacy and safety of limbal-conjunctival autografting with limbal fixation sutures after pterygium excision. Methods: We retrospectively reviewed the records of 90 patients (103 eyes) who received limbal-conjunctival autografts with limbal fixation sutures after excision of the primary pterygium (82 eyes) and recurrent pterygium (21 eyes). Results: The study subjects comprised 41 male patients (47 eyes) and 49 female patients (56 eyes) with a mean age of 51.1 ± 10.5 years (range 32–77). The mean follow-up period was 18.9 ± 9.2 months (range 12–50). Among the 103 eyes, recurrence occurred in 2 eyes (1.9%) after 2 and 4 months, respectively. As complications, 1 case of conjunctival cyst and 2 cases of pseudopterygium at the donor site were reported. Conclusions: Limbal-conjunctival autografting with limbal fixation sutures appears to be an effective and safe method of reducing the recurrence rate after pterygium excision.

show abstract

“…This technique has been associated with low complications and recurrence rates, as well as with improved post-operative comfort and favorable cosmetic results. [789]…”

mentioning

confidence: 99%

Comparison of conjunctival graft thickness after primary and recurrent pterygium surgery: Anterior segment optical coherence tomography study

Ozgurhan

Kara

Bozkurt

et al. 2014

Indian J Ophthalmol

View full text Add to dashboard Cite

Objective:The objective of the following study is to compare the conjunctival graft thickness measured with anterior segment optical coherence tomography (OCT) after primary and recurrent pterygium excision.Design:Prospective, interventional and comparative study.Participants:A total of 20 eyes of 20 patients with primary pterygium (primary group) and 20 eyes of 20 patients with recurrent pterygium (recurrent group) were enrolled.Materials and Methods:All patients underwent pterygium excision with conjunctival autograft transplantation. Conjunctival graft thickness was measured at 1 week, 1 month and 3 months after surgery using the Visante-OCT (Carl-Zeiss Meditec, Dublin, CA, USA). Main outcome measure was the mean conjunctival thickness determined as the mean of three measurements at 1, 2 and 3 mm posterior to the scleral spur.Results:There were no statistically significant differences in age, sex, or laterality between the groups. Mean thickness of the graft in primary and recurrent groups, respectively, was 430 ± 127 μm and 461 ± 178 μm at 1 week after surgery (P = 0.587), 114 ± 19 μm and 162 ± 48 μm at 1 month after surgery (P = 0.001) and 109 ± 15 μm and 107 ± 18 μm at 3 months after surgery (P = 0.726).Conclusion:The findings revealed that conjunctival thickness after primary or recurrent pterygium excision was greatest at 1 week after surgery and continued to decrease for up to 3 months. Mean graft thickness differed significantly between the two groups only at 1 month after surgery.

show abstract

Comparison of Conjunctival Autograft With Amniotic Membrane Transplantation for Pterygium Surgery

Abstract: Although better results in the final appearance were achieved using conjunctival autografting than with AMT, AMT can be a useful alternative in pterygium surgery, especially in those patients who may have a limited amount of conjunctiva for future surgeries.

Cited by 78 publications

References 35 publications

Pterygium Recurrence, Astigmatism and Visual Acuity following Bare-Sclera Excision and Conjunctival Autograft with or without Additional Phototherapeutic Keratectomy

Pterygium Recurrence, Astigmatism and Visual Acuity following Bare-Sclera Excision and Conjunctival Autograft with or without Additional Phototherapeutic Keratectomy

Efficacy and Safety of Limbal-Conjunctival Autografting with Limbal Fixation Sutures after Pterygium Excision

Comparison of conjunctival graft thickness after primary and recurrent pterygium surgery: Anterior segment optical coherence tomography study

Contact Info

Product

Resources

About