Comparison of culture‑negative and culture‑positive sepsis or septic shock: outcomes are more influenced by the nature of the infectious agent itself than by the samples’ positivity

Comparison of the clinical characteristics and clinical outcomes of culture-positive septic shock and culture-negative septic shock among pediatric patients

“…In our study, the proportion of the CNSS group among pediatric patients was not smaller than that of the CPSS group, which is in line with recent retrospective worldwide studies on adult patients [11,[13][14][15]23]. There are several reasons for the occurrence of CNSS.…”

“…Yet, there could be crucial differences between culture-positive septic shock (CPSS) and CNSS, such as pathogenesis, epidemiology, and effectiveness of treatment [9]. Although physicians have studied the clinical outcomes between patients with CPSS and those with CNSS, this subject still requires further investigation [10][11][12][13][14][15].…”

Factors associated with mortality in patients with sepsis and septic shock in the adult intensive care unit of a hospital in Paraguay

“…Esta tendencia se mantiene en otros estudios donde se observa que los pacientes que fallecieron tenían un promedio de edad mayor a los vivos. Esto se explica por la evidencia existente que los sujetos con edades avanzadas presentan un deterioro del (21)(22)(23)(24) sistema inmunitario más marcado en comparación con los pacientes jóvenes .…”

“…El origen infeccioso más frecuente fue el pulmonar, seguida por el foco abdominal y en menor (21)(22)(23)(24)(25)(26)(27) proporción el foco meníngeo, resultado similar a otros estudios hechos en Colombia y España . Sería interesante para próximas investigaciones determinar el efecto de los aislamientos microbianos en la mortalidad de nuestros pacientes.…”