Comparison of cyclofructan-, cyclodextrin-, and polysaccharide-based chiral stationary phases for the separation of pharmaceuticals

Hybridization of helical poly(phenylacetylene)s bearing l-proline tripeptide pendants into porous silica microspheres as a solvent-tolerable chiral stationary phase for liquid chromatography

“…Therefore, obtaining enantiomerically pure isomers is especially important in the preparation and development of biologically active substances, such as drugs. [1][2][3][4] High-performance liquid chromatography (HPLC) is an efficient and economical method for the separation of enantiomers. 5,6 Critical to HPLC-based separation of enantio-mers is the chiral recognition ability of the chiral stationary phase (CSP).…”