For patients undergoing radical prostatectomy, urinary incontinence is not an uncommon postoperative complication. For some, it can resolve over time, while in others the condition persists and requires medical and/or surgical intervention. This summary provides a review of the recommended evaluations to perform in this setting. I ncontinence is one of the most significant complications of a radical prostatectomy (RP). Rates reported after RP range from 2% to 57% depending on the definition used.1-5 This summary will provide an overview of the evidence-based evaluation of incontinence in RP patients.
Causes of post-RP incontinenceAlthough incontinence may be present before RP (reported rates up to 21%), 6-9 preoperative incontinence is likely due to urge incontinence rather than stress incontinence.The most common causes of incontinence post RP are damage to the distal urethral sphincter through direct injury, or injury to the nerve supply or supporting structures.10 While bladder dysfunction can also be present in 26% to 46% of patients postoperatively, it is rarely the sole cause of incontinence in this setting.
11-16Radiation can also be a contributing factor with respect to postoperative incontinence. Among patients who undergo RP after failed radiation therapy, the incidence of urinary incontinence has been reported to be as high as 44%. 17 Reported rates of incontinReported rates of incontinence after radiation and high-intensity focused ultrasound alone are 6.6% to 23% and 0.5% to 15.4%, respectively. [18][19][20] Unpublished data from the Toronto University Health Network demonstrate that, among patients who underwent radiation therapy after RP, the incidence of urinary incontinence was not dependent on the timing of the radiation. Furthermore, those who underwent early radiation (up to six months after surgery: mean 3.6 months) and those who underwent late radiation (after six months: mean 30.1 months) had similar rates of incontinence after the radiation therapy (early: 24.5%; late: 23.3%).
Evidence-based evaluationAll of the recommended evaluations listed below are based on a review of the literature conducted by Herschorn and colleagues as part of the Fourth International Consultation on Incontinence Committee on Surgical Treatment of Urinary Incontinence in Men.21 Table 1 provides a summary of the recommendations, with the levels of evidence and grade of recommendation shown for each.History can provide a great deal of important information in the work-up of the post-RP patient with urinary incontinence. The critical factors to include are age, radiation history, date of surgery, type of surgery (nerve sparing vs. non-nerve sparing) and type of leakage (urge vs. stress; enuresis suggests urge). Other critical factors include time of day and degree of leakage (number of pads), fluid, caffeine and alcohol intake, medications, and other medical conditions.The physical examination typically does not provide a great deal of information, although meatal stenosis, phimosis and retention can be iden...