Comparison of different solvent types for determination biological activities of myrtle berries collected from Turkey

Polat, Büşra; Oba, Şirin; Karaman, Kevser; Arıcı, Muhammet; Sağdıç, Osman

doi:10.3920/qas2013.0241

Cited by 7 publications

(3 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Snoussi et al [ 34 ] found that the antioxidant activity of myrtle berry extract, as evaluated by the DPPH assay, ranged from 67% to 87.5%, depending on the amount of ethanol (60–90%) in the extraction mixture. Polat et al [ 35 ] found that the antioxidant activity of myrtle berry extract, as evaluated by the DPPH assay, ranged from 6.73% to 65.6%, depending on the extracting solvents (70% acetone:water ( v/v ), 80% ethanol:water ( v/v ), 80% methanol:water ( v/v ), and distilled water). Hence, different results can be obtained depending on the processing conditions.…”

Section: Discussionmentioning

confidence: 99%

Liposomal Formulations to Improve Antioxidant Power of Myrtle Berry Extract for Potential Skin Application

et al. 2022

View full text Add to dashboard Cite

Many substances in plant extracts are known for their biological activities. These substances act in different ways, exerting overall protective effects against many diseases, especially skin disorders. However, plant extracts’ health benefits are often limited by low bioavailability. To overcome these limitations, drug delivery systems can be employed. In this study, we evaluated the antioxidant power of an ethanolic extract from Myrtus communis L. (myrtle) berries through colorimetric tests (DPPH and FRAP). The antioxidant activity was also verified by using fibroblast cell culture through cellular Reactive Oxygen Species (ROS) levels measurements. Moreover, the myrtle extract was formulated in phospholipid vesicles to improve its bioavailability and applicability. Myrtle liposomes were characterized by size, surface charge, storage stability, and entrapment efficiency; visualized by using cryo-TEM images; and assayed for cytocompatibility and anti-ROS activity. Our results suggest that myrtle liposomes were cytocompatible and improved the extract’s antioxidant power in fibroblasts, suggesting a potential skin application for these formulations and confirming that nanotechnologies could be a valid tool to enhance plant extracts’ potentialities.

show abstract

Section: Discussionmentioning

confidence: 99%

Liposomal Formulations to Improve Antioxidant Power of Myrtle Berry Extract for Potential Skin Application

et al. 2022

View full text Add to dashboard Cite

show abstract

“…In what concerns, the ability for preventing linoleic acid oxidation, the percentages of inhibition were always above 80%, nevertheless lower than the percentage registered for reference (α-tocopherol); that was 96.31%. The effect of extracting solvents on the total phenolic content, antioxidant, and antiradical activity of extracts of myrtle berry, collected in different places of Turkey, was also studied by Polat et al [ 105 ]. The antioxidant activity, evaluated through the phosphomolybdenum spectrophotometric method, revealed that methanolic extract presented the highest antioxidant value (241.533 mg ascorbic acid equivalents/g dry extract).…”

Section: Introductionmentioning

confidence: 99%

Antioxidant Activity of Myrtus communis L. and Myrtus nivellei Batt. & Trab. Extracts: A Brief Review

2018

View full text Add to dashboard Cite

Myrtus communis L. (myrtle) and Myrtus nivellei Batt. & Trab. (Saharan myrtle) have been used in folk medicine for alleviating some ailments. M. communis is largely distributed in the Mediterranean Basin, whereas M. nivellei is confined in specific zones of the central Saharan mountains. The chemical composition and antioxidant activity of berry and leaf extracts isolated from myrtle are deeply documented, whereas those isolated from Saharan myrtle extracts are less studied. In both species, the major groups of constituents include gallic acid derivatives, flavonols, flavonol derivatives, and hydroxybenzoic acids. In coloured berries, anthocyanins are also present. In M. nivellei extracts are reported for some compounds not described in M. communis so far: 2-hydroxy-1,8-cineole-β-d-glucopyranoside, 2-hydroxy-1,8-cineole 2-O-α-l-arabinofuranosyl (1→6)-β-d-glucopyranoside, rugosin A, and rugosin B. Berries and leaves extracts of both species had antioxidant activity. Comparative studies of the antioxidant activity between leaf and berry myrtle extracts revealed that leaf extracts are best antioxidants, which can be assigned to the galloyl derivatives, flavonols, and flavonols derivatives, although the ratio of these groups of compounds might also have an important role in the antioxidant activity. The anthocyanins present in myrtle berries seem to possess weak antioxidant activity. The antioxidant activity of sample extracts depended on various factors: harvesting time, storage, extraction solvent, extraction type, and plant part used, among other factors. Leaf extracts of myrtle revealed to possess anti-inflammatory activity in several models used. This property has been attributed either to the flavonoids and/or hydrolysable tannins, nevertheless nonprenylated acylphloroglucinols (e.g., myrtucommulone and semimyrtucommulone) have also revealed a remarkable role in that activity. The biological activities of myrtle extracts found so far may direct its use towards for stabilizing complex lipid systems, as prebiotic in food formulations, and as novel therapeutic for the management of inflammation.

show abstract

“…The DPPH method was based on the reduction of a DPPH solution in the presence of antioxidant molecules such as flavonoids and tannins because of their ability to yield hydrogen. Indeed, the antioxidant activity is positively correlated with the high number of hydroxyl groups and the position and nature of the substituents on the B and C rings, in addition to the degree of polymerization of the phenolic compounds (Messaoud & Boussaid, 2011; Polat, Oba, Karaman, Arici, & Sagdic, 2014; Wannes & Marzouk, 2013) owing to their power to give more atoms to stabilize free radicals (Babou et al, 2016; Wannes & Marzouk, 2016). Many current publications have indicated that there is a direct relationship between antioxidant activities and the potency for reducing the components of some plants (Bentabet, Boucherit‐Otmani, & Boucherit, 2014).…”

Section: Discussionmentioning

confidence: 99%

LC–DAD/ESI–MS/MS characterization of phenolic constituents in Rosa canina L. and its protective effect in cells

Fetni

Bertella

Ouahab

2020

Biomedical Chromatography

View full text Add to dashboard Cite

In an aim to prove the efficiency of polyphenols of Rosa canina fruits in promoting human health. A methanolic extract of R. canina fruits was prepared by successive maceration with solvents of increasing polarity. The polyphenol composition was analyzed by HPLC–DAD–ESI–MS. The biological activity of this extract on SH‐SY5Y cells and HepG2 cells was then studied. The antioxidant activity was tested by various in vitro tests such as DPPH‐radical‐scavenging activity, FRAP assay, hydroxyl radical scavenging assay and total antioxidant capacity. The subacute toxicity of R. canina was tested on female rats by repeated intraperitoneal administration of various doses. The phenolic profiles showed 25 antioxidants distributed into three classes of phenolic compounds: glycosylated and agglomerated flavonoids/isoflavonoids, tannins and phenanthrenes. Qualitative phytochemical analyses showed that this extract lacks alkaloids. The methanolic extract of R. canina fruits has a total antioxidant capacity of 82.69 ± 1.18 μg EAA/mg of methanol extract and the IC50 of the methods used is in the following increasing order: FRAP assay (61.88 μg/ml), then hydroxyl radical scavenging assay (67.45 μg/ml) and then DPPH radical‐scavenging activity (129.81 μg/ml). The extract of R. canina did not cause any phenotypic signs of toxicity or mortality during and after treatment. The LD50 was >5,000 mg/kg, hence, R. canina was considered nontoxic. An in vivo study proved the protective effect of R. canina against cardiac and hepato‐renal toxicities. These results drew the importance of a healthy diet, where diets rich in R. canina fruits can be used as a rich natural source of antioxidants and anticarcinogenic phenolic compounds.

show abstract

Comparison of different solvent types for determination biological activities of myrtle berries collected from Turkey

Cited by 7 publications

References 23 publications

Liposomal Formulations to Improve Antioxidant Power of Myrtle Berry Extract for Potential Skin Application

Liposomal Formulations to Improve Antioxidant Power of Myrtle Berry Extract for Potential Skin Application

Antioxidant Activity of Myrtus communis L. and Myrtus nivellei Batt. & Trab. Extracts: A Brief Review

LC–DAD/ESI–MS/MS characterization of phenolic constituents in Rosa canina L. and its protective effect in cells

Contact Info

Product

Resources

About