Comparison of Direct Medical Care Costs Between Erosive Reflux Disease and Non-erosive Reflux Disease in Korean Tertiary Medical Center

Seo, Pyoung Ju; Kim, Nayoung; Oh, Jane C; Lee, Byoung Hwan; Shin, Cheol Min; Suh, Seungchul; Park, Hyunkyung; Nam, Ryoung Hee; Jin, Aizhen; Park, Young Soo; Lee, Dong Hoon

doi:10.5056/jnm.2010.16.3.291

Cited by 4 publications

(6 citation statements)

References 34 publications

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“…These results suggest that not only organic, but also other causes, such as visceral sensitivity, esophageal motility, and psychological factor could influence NERD, which has been proposed in other studies as well 38-40. Previously, we reported that patients with NERD visited emergency center more often and they spent more medical cost than patients with ERD 41. GIS is the scoring system not only for GERD symptom, but also for GERD symptom-induced disturbance in daily life, with consideration of frequency.…”

Section: Discussionmentioning

confidence: 99%

Association of Sleep Dysfunction and Emotional Status With Gastroesophageal Reflux Disease in Korea

Kim¹,

Kim

Seo³

et al. 2013

J Neurogastroenterol Motil

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Background/AimsSleep disturbances and emotional dysfunction are commonly associated with gastroeophageal reflux disease (GERD). The aims of this study were to evaluate GERD symptoms and disturbance in erosive reflux disease (ERD) and nonerosive reflux disease (NERD) patients, and to compare sleep dysfunction, depressive mood, anxiety and quality of life (QOL) among the control, ERD and NERD patients in Korea.MethodsThe Korean subjects were enrolled between 2010 and 2012, classified into 3 groups; the control group with no symptom and normal endoscopic findings, the ERD group with erosive esophagitis and the NERD group with more than one episode of heartburn or acid regurgitation per week, positive response to proton pump inhibitor, and normal endoscopic findings. Questionnaire included GERD symptoms, GERD impact scale (GIS) and daytime pathological sleepiness (Epworth sleepiness scale), sleep dysfunction (Pittsburgh sleep quality index, PSQI), depression and anxiety (Hospital anxiety and depression scale, HADS) and QOL (WHO quality of life scale abbreviated version, WHOQOL-BREF).ResultsA total of 217 subjects were enrolled as follows; control (n = 70), ERD (n = 70) and NERD (n = 77). Impact of symptom of GIS score was higher in the NERD (9.2 ± 0.4) than in the ERD (6.5 ± 0.3) group (P < 0.001). Sleep dysfunctions were more frequent in GERD than the control group (PSQI score [P = 0.021]). Anxiety subscale of HAD score was higher in NERD (7.0 ± 0.5, P = 0.002) and ERD (6.2 ± 0.7, P = 0.004) groups than control (4.3 ± 0.7) group. WHOQOL-BREF scores in NERD (54.9 ± 2.3) and ERD (57.8 ± 2.4) groups were significantly lower than those in the control group (63.8 ± 2.4) (P = 0.002; P = 0.014, respectively). ConclusionsThe patients with NERD than ERD suffered more from the symptoms and disturbance in Korea. Sleep dysfunction and anxiety mood were higher and QOL was decreased in GERD, especially in NERD, suggesting that those factors might affect the severity of NERD.

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Section: Discussionmentioning

confidence: 99%

Association of Sleep Dysfunction and Emotional Status With Gastroesophageal Reflux Disease in Korea

Kim¹,

Kim

Seo³

et al. 2013

J Neurogastroenterol Motil

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“…Recently, the direct medical costs of GERD during one-year follow-up were reported in Korea; the results showed that the erosive reflux disease (ERD) and non-erosive reflux disease (NERD) are similar [17]. That is, the annual direct medical costs of ERD and NERD were $331.3 and $352.2, respectively [17], which are much lower than the costs of PUD in the present study.…”

Section: Discussionmentioning

confidence: 47%

“…That is, the annual direct medical costs of ERD and NERD were $331.3 and $352.2, respectively [17], which are much lower than the costs of PUD in the present study. Furthermore, the distribution of direct medical care cost factors was different in comparisons between these two diseases.…”

Section: Discussionmentioning

confidence: 82%

“…However, there has been no report on the medical care costs of PUD in Korea even though the incidence of PUD has been increasing. For patients with GERD, the analysis of medical costs has helped develop medical policy with the goal of reducing the disease-related costs [17,18]. Furthermore, there have been no reported data on the medical care cost of idiopathic PUD compared with H. pylori (+) and/or NSAID (+) cases.…”

Section: Introductionmentioning

confidence: 99%

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Analysis of direct medical care costs of peptic ulcer disease in a Korean tertiary medical center

Kang

Seo

Kim³

et al. 2011

Scandinavian Journal of Gastroenterology

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“…Health-care systems and individuals incur economic costs for physician visits, medications, and procedures. [28][29][30][31][32][33][34][35] Objective measures such as oesophageal pH monitoring or endoscopy can be used to diagnose gastro-oesophageal reflux disease or its effect on oesophageal mucosa, but these procedures are invasive and can miss cases with fluctuating course. Multiple expert groups have endorsed the use of clinical history and response to therapy in making a clinical diagnosis.…”

Section: Introductionmentioning

confidence: 99%

The global, regional, and national burden of gastro-oesophageal reflux disease in 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017

Dirac¹,

Safiri²,

Tsoi³

et al. 2020

The Lancet Gastroenterology & Hepatology

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Background Gastro-oesophageal reflux disease is a common chronic ailment that causes uncomfortable symptoms and increases the risk of oesophageal adenocarcinoma. We aimed to report the burden of gastro-oesophageal reflux disease in 195 countries and territories between 1990 and 2017, using data from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2017. Methods We did a systematic review to identify measurements of the prevalence of gastro-oesophageal reflux disease in geographically defined populations worldwide between 1990 and 2017. These estimates were analysed with DisMod-MR, a Bayesian mixed-effects meta-regression tool that incorporates predictive covariates and adjustments for differences in study design in a geographical cascade of models. Fitted values for broader geographical units inform prior distributions for finer geographical units. Prevalence was estimated for 195 countries and territories. Reports of the frequency and severity of symptoms among individuals with gastrooesophageal reflux disease were used to estimate the prevalence of cases with no, mild to moderate, or severe to very severe symptoms at a given time; these estimates were multiplied by disability weights to estimate years lived with disability (YLD). Findings Data to estimate gastro-oesophageal reflux disease burden were scant, totalling 144 location-years (unique measurements from a year and location, regardless of whether a study reported them alongside measurements for other locations or years) of prevalence data. These came from six (86%) of seven GBD super-regions, 11 (52%) of 21 GBD regions, and 39 (20%) of 195 countries and territories. Mean estimates of age-standardised prevalence for all locations in 2017 ranged from 4408 cases per 100 000 population to 14 035 cases per 100 000 population. Agestandardised prevalence was highest (>11 000 cases per 100 000 population) in the USA, Italy, Greece, New Zealand, and several countries in Latin America and the Caribbean, north Africa and the Middle East, and eastern Europe; it was lowest (<7000 cases per 100 000 population) in the high-income Asia Pacific, east Asia, Iceland, France, Denmark, and Switzerland. Global prevalence peaked at ages 75-79 years, at 18 820 (95% uncertainty interval [95% UI] 13 770-24 000) cases per 100 000 population. Global age-standardised prevalence was stable between 1990 and 2017 (8791 [95% UI 7772-9834] cases per 100 000 population in 1990 and 8819 [7781-9863] cases per 100 000 population in 2017, percentage change 0•3% [-0•3 to 0•9]), but all-age prevalence increased by 18

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Comparison of Direct Medical Care Costs Between Erosive Reflux Disease and Non-erosive Reflux Disease in Korean Tertiary Medical Center

Cited by 4 publications

References 34 publications

Association of Sleep Dysfunction and Emotional Status With Gastroesophageal Reflux Disease in Korea

Association of Sleep Dysfunction and Emotional Status With Gastroesophageal Reflux Disease in Korea

Analysis of direct medical care costs of peptic ulcer disease in a Korean tertiary medical center

The global, regional, and national burden of gastro-oesophageal reflux disease in 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017

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