Comparison of Early Goal-Directed Therapy With Usual Care for Severe Sepsis and Septic Shock

Gottlieb, Michael; Bailitz, John

doi:10.1016/j.annemergmed.2015.05.025

Cited by 2 publications

(1 citation statement)

References 12 publications

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“…Results from three international independent multicenter trials (ProCESS, ARISE, and ProMISe)8,27,28 showed no benefit of EGDT over standard care. Many systematic reviews and meta-analyses reported that EGDT does not decrease mortality compared with conventional care 29–33. Furthermore, one study showed a worse outcome in the EGDT group compared to conventional care 34.…”

Section: Fluid Resuscitation In Sepsis: Time Types and Dosementioning

confidence: 99%

<p>Septic shock in the ER: diagnostic and management challenges</p>

Worapratya¹,

Wuthisuthimethawee²

2019

OAEM

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Sepsis is a common presentation in the emergency department and a common cause of intensive care unit admissions and death. Accurate triage, rapid recognition, early resuscitation, early antibiotics, and eradication of the source of infection are the key components in delivering quality sepsis care. Evaluation of the patient’s volume status, optimal hemodynamic resuscitation, and evaluation of patient response is crucial for sepsis management in the emergency department.

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Section: Fluid Resuscitation In Sepsis: Time Types and Dosementioning

confidence: 99%

<p>Septic shock in the ER: diagnostic and management challenges</p>

Worapratya¹,

Wuthisuthimethawee²

2019

OAEM

View full text Add to dashboard Cite

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Severe sepsis and septic shock in pre-hospital emergency medicine: survey results of medical directors of emergency medical services concerning antibiotics, blood cultures and algorithms

Casu

Häske

2015

Intern Emerg Med

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Delayed antibiotic treatment for patients in severe sepsis and septic shock decreases the probability of survival. In this survey, medical directors of different emergency medical services (EMS) in Germany were asked if they are prepared for pre-hospital sepsis therapy with antibiotics or special algorithms to evaluate the individual preparations of the different rescue areas for the treatment of patients with this infectious disease. The objective of the survey was to obtain a general picture of the current status of the EMS with respect to rapid antibiotic treatment for sepsis. A total of 166 medical directors were invited to complete a short survey on behalf of the different rescue service districts in Germany via an electronic cover letter. Of the rescue districts, 25.6 % (n = 20) stated that they keep antibiotics on EMS vehicles. In addition, 2.6 % carry blood cultures on the vehicles. The most common antibiotic is ceftriaxone (third generation cephalosporin). In total, 8 (10.3 %) rescue districts use an algorithm for patients with sepsis, severe sepsis or septic shock. Although the German EMS is an emergency physician-based rescue system, special opportunities in the form of antibiotics on emergency physician vehicles are missing. Simultaneously, only 10.3 % of the rescue districts use a special algorithm for sepsis therapy. Sepsis, severe sepsis and septic shock do not appear to be prioritized as highly as these deadly diseases should be in the pre-hospital setting.

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Comparison of Early Goal-Directed Therapy With Usual Care for Severe Sepsis and Septic Shock

Cited by 2 publications

References 12 publications

<p>Septic shock in the ER: diagnostic and management challenges</p>

<p>Septic shock in the ER: diagnostic and management challenges</p>

Severe sepsis and septic shock in pre-hospital emergency medicine: survey results of medical directors of emergency medical services concerning antibiotics, blood cultures and algorithms

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