Comparison of efficacy of amoxicillin versus ciprofloxacin in postsurgical management of transalveolar extraction

Abstract

Background:The transalveolar extraction and the use of pharmacological antibiotic therapy following the surgical procedure in management of postoperative infection go hand in hand in minor oral surgery. Attention has often been focused on antibiotic therapy administered at different time schedules (before or after surgery or both). This investigation reveals how the use of different molecules and dosages is critical in the postoperative period and has always provided positive result.Methodology:A prospective randomized study was carried out in 100 healthy controls of age group 20–50 years undergoing transalveolar extraction in the Department of Oral and Maxillofacial Surgery, Vivekanandha Dental College for Women. A 5-day regimen of amoxicillin or ciprofloxacin group of antibiotics along with regular analgesics was administered to the patients following transalveolar extraction. The patients were evaluated for postoperative infection, inflammation and wound care on postoperative days: day zero, day 2, day 5, day 7, day 15, day 30, and analyzed. A P < 0.05 was considered statistically significant.Results and Conclusion:A total of 100 patients aged 23–50 years (24.6–4.43) met the inclusion criteria. Male accounted for 44, while female were 55, giving male:female ratio 1:1.4. Postoperative infection was minimum with ciprofloxacin group as compared to amoxicillin group and was more significant (P < 0.005) on evaluation. A complete review has also been taken into an account, various strategies used such as surgical flaps, no traumatic osteotomy, and primary or secondary closure.

Cinnamaldehyde as antimicrobial in cellulose‐based dental appliances

“…In addition, synergistic effects are also observed with conventional antimicrobials such as cefotaxime and ciprofloxacin (Dhara & Tripathi, 2020). This could be useful when considering surgery prior to the use of dental appliances where such antimicrobials could be used (Natarajan et al, 2017). Finally, the good compatibility of cinnamaldehyde with other natural compounds such as carvacrol and eugenol makes it possible to combine such ingredients in the material.…”

Antibiotic Prescribing Practices of Endodontic Postgraduate Trainees in Karachi, Pakistan

“…There is no need of antibiotic prescription in an otherwise healthy patient. 27 However, still 58.5% of the clinicians chose prescribing antibiotics as an option. Comparable results were seen in few other studies conducted in United States.…”

Synthesis and Characterization of Metal Phthalocyanine Complex Using Substituted 4-Nitrophthalonitrile Ligand

“…Various biomolecules like proteins and peptides can link to phthalocyanine dyes which are therefore, used in bioanalytical and bioimaging fields (Yang et al, 2020). Natarajan et al (2017) synthesized a form of phthalocyanines which are hydrophobic axial groups, but contains both hydrophilic groups and a reactive group that is attached to the benzo-ring. Another metalloid like silicon can replace copper in this structure which will allow it to have two axial ligands (Natarajan et al 2017).…”

“…Natarajan et al (2017) synthesized a form of phthalocyanines which are hydrophobic axial groups, but contains both hydrophilic groups and a reactive group that is attached to the benzo-ring. Another metalloid like silicon can replace copper in this structure which will allow it to have two axial ligands (Natarajan et al 2017).…”