Comparison of enzymatic and non-enzymatic glucose sensors based on hierarchical Au-Ni alloy with conductive polymer

Lee, Won‐Chul; Kim, Kwang‐Bok; Gurudatt, N.G.; Hussain, Khalil K.; Choi, Cheol Soo; Park, Deog-Su; Shim, Yoon‐Bo

doi:10.1016/j.bios.2019.01.028

Cited by 209 publications

(84 citation statements)

References 25 publications

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“…The CPs aid in increasing the stability and enhancing the electrochemical capacity of the electrodes. In contrast, biosensors are highly specific and less vulnerable to interference, but the working conditions and stability are still major drawbacks [132]. The measurements are performed in alkaline solution, which is not very attractive to patients with diabetes mellitus, and the linear range is very narrow, falls short of the required limit of 25-30 mM.…”

Section: Non-enzymatic Detection Of Glucosementioning

confidence: 99%

Recent Advances of Conducting Polymers and Their Composites for Electrochemical Biosensing Applications

Luong

Narayan

Solanki

et al. 2020

JFB

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Conducting polymers (CPs) have been at the center of research owing to their metal-like electrochemical properties and polymer-like dispersion nature. CPs and their composites serve as ideal functional materials for diversified biomedical applications like drug delivery, tissue engineering, and diagnostics. There have also been numerous biosensing platforms based on polyaniline (PANI), polypyrrole (PPY), polythiophene (PTP), and their composites. Based on their unique properties and extensive use in biosensing matrices, updated information on novel CPs and their role is appealing. This review focuses on the properties and performance of biosensing matrices based on CPs reported in the last three years. The salient features of CPs like PANI, PPY, PTP, and their composites with nanoparticles, carbon materials, etc. are outlined along with respective examples. A description of mediator conjugated biosensor designs and enzymeless CPs based glucose sensing has also been included. The future research trends with required improvements to improve the analytical performance of CP-biosensing devices have also been addressed.

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Section: Non-enzymatic Detection Of Glucosementioning

confidence: 99%

Recent Advances of Conducting Polymers and Their Composites for Electrochemical Biosensing Applications

Luong

Narayan

Solanki

et al. 2020

JFB

View full text Add to dashboard Cite

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“…It has become one of the greatest threats to human health globally. [1][2][3][4] The World Health Organization reports that 578 million people will suffer from diabetes worldwide by 2030. [5] Compared with other acute and chronic diseases, diabetes can cause kidney failure, stroke, blindness, [6,7] cerebrocardiovascular diseases, and associated complications.…”

Section: Introductionmentioning

confidence: 99%

Metal–Organic Framework‐Derived Nickel/Cobalt‐Based Nanohybrids for Sensing Non‐Enzymatic Glucose

Wang

Hou

et al. 2020

ChemElectroChem

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The daily detection of blood glucose levels has become a major concern globally because blood glucose levels are related to human health. Composites comprising non-noble metal nanomaterials and highly conductive carbon materials are active and selective catalysts for glucose detection in non-enzyme sensors, and are therefore particularly attractive. In the present study, we prepared nickel/cobalt (NiCo) alloy nano-particles encapsulated in graphitized carbon by pyrolyzing a bimetallic (Ni and Co) metal organic framework (NiCo-MOF) at 800°C under a nitrogen atmosphere (denoted NiCo/C). In the linear range 0.5 μM-4.38 mM, a non-enzymatic glucose sensor comprising SPE/NiCo/C (SPE = screen-printed electrode) exhibited a high sensitivity of 265.53 μA mM À 1 cm À 2 , with a low detection limit of 0.2 μM (S/N = 3). The NiCo/C sensor had good selectivity for the amperometric detection of glucose. Glucose levels were measured with acceptable reliability and accuracy in human serum samples. The current work offers an alternative tool for diagnosing diabetes and monitoring daily blood glucose levels.

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“…To address the need for easy, rapid and reliable glucose sensing with low cost, various non-enzymatic methods have been investigated and developed [14][15][16]. Among these methods, the molecularly imprinting (MIP) approach has attracted much attention.…”

Section: Introductionmentioning

confidence: 99%

A Low-Cost Paper Glucose Sensor with Molecularly Imprinted Polyaniline Electrode

Chen

Wright

Dincel

et al. 2020

Sensors

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For the hundreds of millions of worldwide diabetic patients, glucose test strips are the most important and commonly used tool for monitoring blood glucose levels. Commercial test strips use glucose oxidases as recognition agents, which increases the cost and reduces the durability of test strips. To lower the cost of glucose sensors, we developed a paper-based electrical sensor with molecularly imprinted glucose recognition sites and demonstrated the determination of various glucose concentrations in bovine blood solutions. The sensing electrode is integrated with molecular recognition sites in the conductive polymer. A calibration graph as a function of glucose concentration in aqueous solution was acquired and matched with a correlation coefficient of 0.989. We also demonstrated the determination of the added glucose concentrations ranging from 2.2 to 11.1 mM in bovine blood samples with a linear correlation coefficient of 0.984. This non-enzymatic glucose sensor has the potential to reduce the health care cost of test strips as well as make glucose sensor test strips more accessible to underserved communities.

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Comparison of enzymatic and non-enzymatic glucose sensors based on hierarchical Au-Ni alloy with conductive polymer

Cited by 209 publications

References 25 publications

Recent Advances of Conducting Polymers and Their Composites for Electrochemical Biosensing Applications

Recent Advances of Conducting Polymers and Their Composites for Electrochemical Biosensing Applications

Metal–Organic Framework‐Derived Nickel/Cobalt‐Based Nanohybrids for Sensing Non‐Enzymatic Glucose

A Low-Cost Paper Glucose Sensor with Molecularly Imprinted Polyaniline Electrode

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