1985
DOI: 10.1016/s0022-3468(85)80210-4
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Comparison of fetal, newborn, and adult wound healing by histologic, enzyme-histochemical, and hydroxyproline determinations

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Cited by 210 publications
(31 citation statements)
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“…It was further hoped that we could take advantage of the superior healing of the fetus [15, 16, 17, 18, 19, 20]. Unfortunately, this did not turn out to be the case.…”
Section: Discussionmentioning
confidence: 99%
“…It was further hoped that we could take advantage of the superior healing of the fetus [15, 16, 17, 18, 19, 20]. Unfortunately, this did not turn out to be the case.…”
Section: Discussionmentioning
confidence: 99%
“…It was reported that the fetus has a faster wound healing progress without leaving scars compared to that occurs in adults . Moreover, a more organized collagen was formed unlike that found in adults (Scott Adzick et al, 1985). The peculiar characteristics of the fetal healing were attributed to the HA rich extracellular matrix of the healing tissue (Adzick and Longaker, 1992;Longaker et al, 1991).…”
Section: Introductionmentioning
confidence: 92%
“…The infiltration of neutrophils which characterizes the early postnatal wound is greatly diminished in fetal wounds [5]. The number of tissue macrophages in the subsequent stages of wound healing is also decreased.…”
Section: Inflammatory Response and Cytokinesmentioning
confidence: 99%
“…In contrast, the fetus is known to heal cutaneous wounds without a scar by regeneration of normal dermal architecture including restoration of dermal appendages and neurovasculature [5, 6▪]. This regenerative capability occurs in the mid-gestational period and has been demonstrated in all mammalian species studied to date, including humans, mice, rats, sheep, and monkeys.…”
Section: Introductionmentioning
confidence: 99%