Comparison of Growth Rate Between Gastric Cancer and Colon Cancer and It's Significance

Akimoto, Ryuichi; Mai, Masayoshi; Kusama, Satoru

doi:10.5833/jjgs.17.2242

Cited by 2 publications

(1 citation statement)

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“…Takahashi et al [36] calculated that the minimum implantable size of a metastasis is 2 5 cells x 10 µm, the size of a single cancer cell [10]. In our previous study regarding microsatellite liver metastases [13][14][15], the minimum detectable size of microscopic lesions surrounding the macroscopic metastases was 100 µm.…”

Section: Discussionmentioning

confidence: 99%

Procedures of Choice for Resection of Primary and Recurrent Liver Metastases from Colorectal Cancer

et al. 2004

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Although liver resection offers the only realistic chance of cure for patients with liver metastases from colorectal cancer, no consensus exists as to the procedure of choice for managing these tumors. Data from 193 patients who underwent hepatectomy for liver metastases from colorectal cancer and 26 of 193 patients who underwent repeat hepatectomy for recurrent metastases were collected. The suitability of resection was evaluated retrospectively based on known risk factors for recurrence and patterns of recurrence. On multivariate analysis, a positive surgical margin (SM+) was the only risk factor for recurrence after the initial resection (p < 0.01). SM+ (p < 0.01) and nonanatomic resection (p < 0.05) that was less than a sectionectomy (p < 0.05) were risk factors for recurrence after repeat hepatectomy. Multiple tumors (four or more) was the most common pattern of recurrence after initial hepatectomy, and recurrence close to the line of resection was most common after repeat hepatectomy. Based on tumor doubling times, recurrence after initial hepatectomy seemed to originate from the primary colorectal lesion, whereas recurrence after repeat hepatectomy was derived from a hepatic metastasis. Retrospective analysis suggests that hepatectomy with clear surgical margins is more important than anatomic resection for initial hepatectomy, and at least sectionectomy is necessary for repeat hepatectomy.

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Section: Discussionmentioning

confidence: 99%

Procedures of Choice for Resection of Primary and Recurrent Liver Metastases from Colorectal Cancer

et al. 2004

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Establishment of a human chorionic gonadotropin‐producing human gastric carcinoma in nude mice

Ueno

Mai

1991

Journal of Surgical Oncology

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A human chorionic gonadotropin (HCG)-producing gastric carcinoma was transplanted into BALB/c nu/nu nude mice. The original tumor tissue had been obtained by gastrectomy from a 55-year-old patient with gastric carcinoma. The tumor was transplanted serially in nude mice, and its doubling time was stable to approximately 12 days. A positive correlation was observed between serum HCG level and tumor weight. The serum HCG level of the mice and the histology of the tumor weight. The serum HCG level of the mice and the histology of the tumor, papillary adenocarcinoma with partial poorly differentiated adenocarcinoma, did not change on serial transfers. HCG was positively stained by an immunochemical technique only in the site of the poorly differentiated adenocarcinoma, while staining was negative in the site of the papillary adenocarcinoma, which constituted most of the tumor. These results indicate that this tumor in nude mice will be useful not only as a therapeutic experimental system but also for studying the potential malignancy of HCG-producing cancer cells.

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Comparison of Growth Rate Between Gastric Cancer and Colon Cancer and It's Significance

Cited by 2 publications

References 0 publications

Procedures of Choice for Resection of Primary and Recurrent Liver Metastases from Colorectal Cancer

Procedures of Choice for Resection of Primary and Recurrent Liver Metastases from Colorectal Cancer

Establishment of a human chorionic gonadotropin‐producing human gastric carcinoma in nude mice

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