Comparison of Inconvenience Costs Between Influenza Antivirals for Japanese Pediatric Patients: A Conjoint Analysis of Parental Responses

Abstract

Introduction: Certain drug characteristics, including dosage and form, are associated with either convenience or inconvenience for the patients taking them, and any inconvenience can be considered as a ''cost'' in disease treatment. Multiple antivirals are available for influenza in Japan, with various dosages and forms. This study evaluated the inconvenience costs associated with influenza antivirals for pediatric patients by using conjoint analysis on responses from their parents. Methods: An online survey (May 2021) was conducted for parents whose child took antivirals for influenza at 6-11 years during the 3 years until March 2021. Attributes of the

Estimation of Intangible Costs for Factors Associated with Oral Antiviral Drugs for COVID-19 Treatment: A Conjoint Analysis in Japan

“…Regarding the formulation and size, lower intangible costs for small compared to large seemed reasonable. The lower intangible costs of tablets compared to capsules were similar to those in a previous study on preferences for influenza antivirals in Japanese pediatric patients [2].…”

“…In addition to critical factors such as efficacy and safety, studies have recently reported intangible costs for various factors related to disease prevention and treatment. Previous studies indicated the value of convenience for factors associated with medication, such as administration route and dosage, using a conjoint analysis [1,2], which is an established method to assess consumer preference in market research, and has been increasingly used in medical research [1][2][3][4][5][6][7][8].…”

Prescription factors influencing baloxavir prescription during the 2018/2019 and 2019/2020 seasons: a administrative database study in Japan

“…A previous online survey on parents reported that parents also prefer oral, short-term, less-frequent (once daily) anti-influenza drugs for their children [ 11 ], although the adjusted odds ratio of baloxavir prescription was lower in children. Pediatricians have a greater tendency to adhere to guidelines compared with physicians working in other medical disciplines [ 13 ]. Differences in preferences among clinical departments are likely to have led to the difference in the baloxavir prescription rate according to age.…”

Analysis of Emotional Stress of Teachers in Japanese Teaching Process Based on EEG Signal Analysis

“…Some recent literatures have proved that it is a feasible method to use resting state EEG detection and classifier to identify teachers' emotional stress relief during Japanese teaching. In the resting state EEG samples including 34 cases of teachers' emotional stress relief in the process of Japanese teaching and 30 cases of normal controls, the classification accuracy of 93.33% was achieved by using relative wavelet energy and Alpha frequency power [ 18 , 19 ]. In addition, nonlinear features such as fractal dimension and maximum Lyapunov index were used in EEG data collected from 15 and 15 normal people, and the recognition accuracy of SVM classifier reached 98% [ 20 ].…”