Comparison of lipid accumulation product with body mass index as an indicator of hypertension risk among Mongolians in China

Gao, Xiuren; Wang, Guiyan; Wang, Aili; Xu, Tan; Tong, Weijun; Zhang, Yonghong

doi:10.1016/j.orcp.2012.02.002

Cited by 31 publications

(44 citation statements)

References 31 publications

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“…Also, previous studies reported that LAP better than other variables (e.g., BMI and WC) predicted MetS, DM2, and CVD …”

Section: Discussionmentioning

confidence: 86%

“…The majority of previous studies reported VAI and LAP to be reliable indices in prediction of many metabolic disturbances …”

Section: Discussionmentioning

confidence: 99%

“…Even though a large number of studies in adult population indicate VAI and LAP as reliable markers of cardiometabolic risk advantageous over BMI and WC, there are another ones that report the opposite …”

Section: Introductionmentioning

confidence: 97%

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Are visceral adiposity index and lipid accumulation product reliable indices for metabolic disturbances in patients with type 2 diabetes mellitus?

Kavarić

Klisić

Ninić

2017

Clinical Laboratory Analysis

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“…Also, previous studies reported that LAP better than other variables (e.g., BMI and WC) predicted MetS, DM2, and CVD …”

Section: Discussionmentioning

confidence: 86%

“…The majority of previous studies reported VAI and LAP to be reliable indices in prediction of many metabolic disturbances …”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Are visceral adiposity index and lipid accumulation product reliable indices for metabolic disturbances in patients with type 2 diabetes mellitus?

Kavarić

Klisić

Ninić

2017

Clinical Laboratory Analysis

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show abstract

“…However, few studies have examined the association between LAP and stroke incidence. Moreover, a previous study indicated that increased LAP was positively and significantly associated with the risk of prevalent hypertension among Inner Mongolians 15) , while the cumulative effect of LAP and hypertension on the development of stroke has not been sufficiently studied.…”

Section: Data Collectionmentioning

confidence: 99%

“…Previous studies suggested that the simultaneous presence of an elevated fasting triglyceride (TG) concentration and an increased WC could distinguish visceral adiposity from subcutaneous abdominal fat 12,13) . Lipid accumulation product (LAP), which is a concept of a combination of WC and TG, is considerably superior than body mass index (BMI) and WC for identifying adults with CVD [14][15][16] . A prospective study demonstrated that the LAP was independently associated with an increased risk of incident CVD among women after 8.6 years of follow-up 17) .…”

Section: Data Collectionmentioning

confidence: 99%

Lipid Accumulation Product and Hypertension Related to Stroke: a 9.2-Year Prospective Study Among Mongolians in China

Zhong

Xia

Zhong

et al. 2016

J Atheroscler Thromb

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Cox proportional hazards models and receiver operating characteristic (ROC) curves were used to evaluate the associations between LAP, hypertension, and stroke incidence. Results: During the follow-up period, a total of 121 stroke events were observed. Participants with higher LAP were associated with higher risk of stroke [adjusted hazard ratio (HR), 1.67; 95% confidence interval (CI), 1.08 -2.58] than the participants in the lower LAP group. However, no significant dose -response relationship was detected between LAP levels and risk of stroke (P -trend 0.103). The Kaplan -Meier curves showed that hypertensives with high LAP had highest cumulative stroke incidence rate (log-rank P 0.001). The multivariate-adjusted HRs (95% CIs) of stroke for normotensives with high LAP, hypertensives with low LAP, and hypertensives with high LAP were 1.80 (0.84 -3.89), 2.94 (1.51 -5.74), and 4.23 (2.15 -8.34), respectively, compared with normotensives with low LAP. Conclusions: The present study showed that high LAP was associated with an increased risk of future stroke, and hypertensives with high LAP had the highest risk of stroke among Inner Mongolians. These findings indicate that LAP and hypertension may be valuable to predict and prevent stroke incidence.J Atheroscler Thromb, 2016; 23: 830-838.

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Association of adiposity with diabetes: A national research among Chinese adults

Wang

Zou

et al. 2020

Diabetes Metabolism Res

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Background Adiposity is an established risk factor for diabetes. The different measurements of adiposity for predicting diabetes have been compared in recent studies in Western countries. However, similar researches among Chinese adults are limited. Methods Data were collected from a national survey conducted during September 2014 and May 2015 Among Chinese adults aged 40 years and older across 30 China's provinces. Multilevel model analysis was performed to examine the impacts of different obesity indices [body mass index (BMI), waist circumference (WC), lipid accumulation product index (LAP), visceral adiposity index (VAI), and body adiposity index (BAI)] on the risk of diabetes. Results A total of 162 880 participants were included in this study. Of them, 54.47% were female. With an increase in BMI, WC, LAP, VAI, and BAI, the prevalence of diabetes significantly grew (P < 0.001). The multilevel model analysis showed that WC has the strongest impact on diabetes prevalence, while BAI was the weakest. For one SD increment in BMI, WC, LAP, VAI, and BAI, the prevalence of diabetes increased by 27.0% (Odds Ratio (OR) = 1.270, 95% Confidence interval (CI) = 1.251–1.289), 37.4% (OR = 1.374, 95% CI = 1.346–1.401), 28.1% (OR = 1.281, 95% CI = 1.266–1.297), 22.0% (OR = 1.220, 95% CI = 1.204–1.236), and 17.4% (OR = 1.174, 95% CI = 1.151–1.192), respectively. Conclusion Obesity indicators of BMI, WC, LAP, VAI, and BAI have significant positive relationships with the risk of diabetes. WC has the strongest impact on diabetes, while BAI has the weakest.

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Comparison of lipid accumulation product with body mass index as an indicator of hypertension risk among Mongolians in China

Cited by 31 publications

References 31 publications

Are visceral adiposity index and lipid accumulation product reliable indices for metabolic disturbances in patients with type 2 diabetes mellitus?

Are visceral adiposity index and lipid accumulation product reliable indices for metabolic disturbances in patients with type 2 diabetes mellitus?

Lipid Accumulation Product and Hypertension Related to Stroke: a 9.2-Year Prospective Study Among Mongolians in China

Association of adiposity with diabetes: A national research among Chinese adults

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