Comparison of Nail Polish Meth(Acrylates) (MA) Gel Photoresist and Vinyl Adhesive Paper for Low-Cost Microfluidics Fabrication

Thach, Ha; Nguyen, Hoang-Tuan; Tong, Uyen; Hoang, Tuan Anh; Vuong, Tuan-Anh; Perrault, Cécile M.; Huynh, Khon

doi:10.1007/978-981-13-5859-3_57

Cited by 3 publications

(2 citation statements)

References 12 publications

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“…To address the problems associated with high-cost MF devices, low-cost MF fabrication has been proposed [ 31 ]. Nguyen and colleagues (2018) [ 27 ] recommended an MF fabrication method that provides high sensitivity and lowers cost by reducing the number of reagents and analysis time.…”

Section: Fundamentals Of Microfluidicsmentioning

confidence: 99%

Microfluidics for Peptidomics, Proteomics, and Cell Analysis

et al. 2021

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Microfluidics is the advanced microtechnology of fluid manipulation in channels with at least one dimension in the range of 1–100 microns. Microfluidic technology offers a growing number of tools for manipulating small volumes of fluid to control chemical, biological, and physical processes relevant to separation, analysis, and detection. Currently, microfluidic devices play an important role in many biological, chemical, physical, biotechnological and engineering applications. There are numerous ways to fabricate the necessary microchannels and integrate them into microfluidic platforms. In peptidomics and proteomics, microfluidics is often used in combination with mass spectrometric (MS) analysis. This review provides an overview of using microfluidic systems for peptidomics, proteomics and cell analysis. The application of microfluidics in combination with MS detection and other novel techniques to answer clinical questions is also discussed in the context of disease diagnosis and therapy. Recent developments and applications of capillary and microchip (electro)separation methods in proteomic and peptidomic analysis are summarized. The state of the art of microchip platforms for cell sorting and single-cell analysis is also discussed. Advances in detection methods are reported, and new applications in proteomics and peptidomics, quality control of peptide and protein pharmaceuticals, analysis of proteins and peptides in biomatrices and determination of their physicochemical parameters are highlighted.

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Section: Fundamentals Of Microfluidicsmentioning

confidence: 99%

Microfluidics for Peptidomics, Proteomics, and Cell Analysis

et al. 2021

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“…14 In resource limited settings where industrial-/research-grade instrumentation for printed electronics and microfluidics became unaffordable, alternative approaches to implement integrated microfluidic sensors have flourished. 18,23 Microfluidic devices have been fabricated using everyday items such as correction pens, 20 nail polish, 22,26 wax printers, 24,25 commercial craft cutters 27 and shrink thermoplastics. 28,29 3D printing is also an increasingly common option for reproducible, low-cost devices, despite its disadvantages of having limited printable materials and low production throughput.…”

Section: Introductionmentioning

confidence: 99%

Low-cost and rapid prototyping of integrated electrochemical microfluidic platforms using consumer-grade off-the-shelf tools and materials

et al. 2022

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Low-cost and cleanroom-free prototyping of microfluidic and electrochemical biosensors: Techniques in fabrication and bioconjugation

2021

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Integrated microfluidic biosensors enable powerful microscale analyses in biology, physics, and chemistry. However, conventional methods for fabrication of biosensors are dependent on cleanroom-based approaches requiring facilities that are expensive and are limited in access. This is especially prohibitive toward researchers in low- and middle-income countries. In this topical review, we introduce a selection of state-of-the-art, low-cost prototyping approaches of microfluidics devices and miniature sensor electronics for the fabrication of sensor devices, with focus on electrochemical biosensors. Approaches explored include xurography, cleanroom-free soft lithography, paper analytical devices, screen-printing, inkjet printing, and direct ink writing. Also reviewed are selected surface modification strategies for bio-conjugates, as well as examples of applications of low-cost microfabrication in biosensors. We also highlight several factors for consideration when selecting microfabrication methods appropriate for a project. Finally, we share our outlook on the impact of these low-cost prototyping strategies on research and development. Our goal for this review is to provide a starting point for researchers seeking to explore microfluidics and biosensors with lower entry barriers and smaller starting investment, especially ones from low resource settings.

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Comparison of Nail Polish Meth(Acrylates) (MA) Gel Photoresist and Vinyl Adhesive Paper for Low-Cost Microfluidics Fabrication

Cited by 3 publications

References 12 publications

Microfluidics for Peptidomics, Proteomics, and Cell Analysis

Microfluidics for Peptidomics, Proteomics, and Cell Analysis

Low-cost and rapid prototyping of integrated electrochemical microfluidic platforms using consumer-grade off-the-shelf tools and materials

Low-cost and cleanroom-free prototyping of microfluidic and electrochemical biosensors: Techniques in fabrication and bioconjugation

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