Comparison of Novel Risk Markers for Improvement in Cardiovascular Risk Assessment in Intermediate-Risk Individuals

Yeboah, Joseph; McClelland, Robyn L.; Polonsky, Tamar S.; Burke, Gregory L.; Sibley, Christopher T.; O’Leary, Daniel H.; Carr, J. Jeffrey; Goff, David C.; Greenland, Philip; Herrington, David M.

doi:10.1001/jama.2012.9624

Cited by 988 publications

(669 citation statements)

References 27 publications

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“…CAC has been shown to be the best predictor of future events in the general population, 13e15 the elderly, 13,17 and in persons with diabetes. 18 It provides more robust risk prediction than carotid IMT, C-reactive protein, ankle-brachial index, and family history of premature heart disease 19 Incorporating CAC into the Multi-Ethnic Study of Atherosclerosis (MESA) clearly improves risk stratification and discrimination over scores based on chronologic age. 20 CAC has been shown to better identify those asymptomatic individuals who would benefit from statins, 21 aspirin, 22 ACE inhibitors 23 or the polypill 24 than risk calculators or other biomarkers.…”

Section: Evidence Supporting Cac For Risk Assessmentmentioning

confidence: 99%

2016 SCCT/STR guidelines for coronary artery calcium scoring of noncontrast noncardiac chest CT scans: A report of the Society of Cardiovascular Computed Tomography and Society of Thoracic Radiology

Hecht

Cronin

Blaha

et al. 2017

Journal of Cardiovascular Computed Tomography

362

231

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Section: Evidence Supporting Cac For Risk Assessmentmentioning

confidence: 99%

2016 SCCT/STR guidelines for coronary artery calcium scoring of noncontrast noncardiac chest CT scans: A report of the Society of Cardiovascular Computed Tomography and Society of Thoracic Radiology

Hecht

Cronin

Blaha

et al. 2017

Journal of Cardiovascular Computed Tomography

362

231

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“…an estimated 10-year event risk of 5%-20% based on traditional cardiovascular screening. [46,48,[68][69][70][71][72][73] Two retrospective cohort studies have evaluated CACS in women with a history of hypertensive pregnancy disorders, and both found a positive association between CACS and self-reported hypertension in pregnancy. [74,75] There are no published prospective studies yet to evaluate CACS in previous preeclamptic patients.…”

Section: Coronary Artery Calcium Scorementioning

confidence: 99%

Determinants of future cardiovascular health in women with a history of preeclampsia

et al. 2015

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Please cite this article as: Zoet Gerbrand A, Koster Maria PH, Velthuis Birgitta K, de Groot Christianne JM, Maas Angela HEM, Fauser Bart CJM, Franx Arie, Rijn Bas B.van.Determinants of future cardiovascular health in women with a history of preeclampsia.Maturitas http://dx.doi.org/10.1016/j.maturitas. 2015.07.004 This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. Keywords:Preeclampsia, cardiovascular disease, risk assessment, screening, prevention Highlights  Female-specific risk factors, among which preeclampsia, may have additional value in cardiovascular screening.  Non-invasive imaging techniques can be helpful to detect early-stage cardiovascular lesions as a sign of subclinical atherosclerotic disease.  Preliminary studies show positive effects of short-term lifestyle interventions following preeclampsia.  There is a need for clinical practice guidelines that provide long-term strategies in women after preeclampsia in pregnancy to improve cardiovascular health. AbstractWomen who develop preeclampsia have an increased risk of cardiovascular disease (CVD) later in life.However, current guidelines on cardiovascular risk assessment and prevention are unclear on how and when to screen these women postpartum, and about the role of a positive history of preeclampsia in later-life CVD risk management. The aim of this review is to discuss the present knowledge on commonly used cardiovascular screening modalities available to women with a history of preeclampsia, and to discuss recent developments in early detection of CVD using cardiovascular imaging.Furthermore, we explore how female-specific risk factors may have additional value in cardiovascular screening, in particular in relatively young women, although their implementation in clinical practice is challenged by inconsistent results and lack of long-term outcome data. Non-invasive imaging techniques, e.g. coronary artery intima-media thickness (CIMT), can be helpful to detect subclinical atherosclerotic disease, and coronary artery calcium scoring (CACS) has shown to be effective in early detection of cardiovascular damage. However, whilst more short-term and long-term follow-up studies are becoming available, few studies have investigated women with a history of preeclampsia in the fourth and fifth decade of life, when early signs of premature CVD are most likely to become apparent.Further studies are needed to inform new and improved clinical practice guidelines, and provide longterm strategies to effectively prevent CVD, specifically targeted at women with a history of preeclampsia. Additionally, evaluation of feasibility, cost-effectiveness ...

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“…Criqui et al58 reported that the use of the Agatston score in assessing CAC progression is problematic since an increase in CAC could be caused by an increase in volume, an increase in density, or both. So despite the studies suggesting a strong predictive value of CAC for CVD, there has been little rigorous comparison of what specific measure of CAC is most predictive 59. In order to clarify the clinical significance of these factors, Criqui et al58 conducted a multicenter, prospective observational study of the MESA cohort to determine the independent associations of CAC volume and CAC density with incident CVD events.…”

Section: Multimodality Imaging Techniquesmentioning

confidence: 99%

Imaging Cardiovascular Calcification

Wang

Osborne

Tung

et al. 2018

JAHA

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Comparison of Novel Risk Markers for Improvement in Cardiovascular Risk Assessment in Intermediate-Risk Individuals

Cited by 988 publications

References 27 publications

2016 SCCT/STR guidelines for coronary artery calcium scoring of noncontrast noncardiac chest CT scans: A report of the Society of Cardiovascular Computed Tomography and Society of Thoracic Radiology

2016 SCCT/STR guidelines for coronary artery calcium scoring of noncontrast noncardiac chest CT scans: A report of the Society of Cardiovascular Computed Tomography and Society of Thoracic Radiology

Determinants of future cardiovascular health in women with a history of preeclampsia

Imaging Cardiovascular Calcification

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