Comparison of Percutaneous Image-Guided Microwave Ablation and Cryoablation for Sarcoma Lung Metastases: A 10-Year Experience

Bourgouin, P.; Wróbel, Maria; Mercaldo, Nathaniel D.; Murphy, Mark C.; Leppelmann, Konstantin S; Levesque, Vincent M.; Muniappan, Ashok; Silverman, Stuart G.; Shepard, Jo-Anne O.; Shyn, Paul B.; Fintelmann, Florian J.

doi:10.2214/ajr.21.26551

Cited by 23 publications

(13 citation statements)

References 46 publications

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“…Previous studies have shown that the duration of surgery and ablation of the free edge of the tumor are significantly related to the size of the tumor, and the ablation edge beyond the edge of the tumor by at least 5 mm is a key factor in ensuring complete ablation ( 24 , 25 ). Our study demonstrated that for lung tumors adjacent to the pleura, complete ablation was achieved in most tumors, even if the margin of the tumor was <5 mm away from the pleura.…”

Section: Discussionmentioning

confidence: 99%

Local ablation of pulmonary malignancies abutting pleura: Evaluation of midterm local efficacy and safety

Zhao

Guo

et al. 2022

Front. Oncol.

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ObjectiveTo retrospectively evaluate the efficacy and safety of local ablation treatment for adjacent pleural lung tumors.Materials and methodsSixty-two patients who underwent pulmonary nodule ablation at the Affiliated Cancer Hospital of Zhengzhou University were enrolled between January 2016 and December 2020. All patients were followed up with enhanced computed tomography or magnetic resonance imaging within 48 h after treatment and 2, 4, 6, 9, and 12 months after treatment. All patients were followed for at least 12 months.ResultsA total of 84 targeted tumors (62 patients) underwent 94 ablations. In the 12-month follow-up images, 69 of the 84 targeted tumors were completely ablated, 15 had incomplete ablation, and the 12-month incomplete ablation rate was 17.8% (15/84). Of the 15 incompletely ablated tumors, six had partial responses, five had stable disease, and four had progressive disease. The most common adverse event was pneumothorax, with an incidence of 54.8% (34/62). The second most common complication was pleural effusion, with an incidence rate of 41.9% (26/62). The incidence of needle-tract bleeding was 21% (13/62) and all patients were cured using hemostatic drugs. Serious complications were bronchopleural fistula in four patients (6.5%, 4/62) and needle tract metastasis in one patient. Four cases of bronchopleural fistula were found in the early stages and were cured after symptomatic treatment.ConclusionLocal ablation is effective for the treatment of adjacent pleural lung tumors, and its operation is safe and controllable.

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Section: Discussionmentioning

confidence: 99%

Local ablation of pulmonary malignancies abutting pleura: Evaluation of midterm local efficacy and safety

Zhao

Guo

et al. 2022

Front. Oncol.

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“…Kurilova et al showed that three or more lines of pre-ablation chemotherapy with or without targeted therapy was a negative prognostic factor after MWA [ 21 ]. Other negative prognostic factors in the previous studies included a larger number of lung metastases [ 12 , 19 , 29 ], a larger tumor size [ 12 , 20 , 22 ], rectal rather than colon cancer [ 18 ], a shorter progression-free interval [ 19 ], a worse response to RFA [ 31 ], and a lack of repeated RFA [ 33 ].…”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

“…The main series of ablative therapies for lung metastases from sarcoma are summarized in Table 3 [ 12 , 33 – 36 ]. RFA was always performed in the listed studies, except for the most recent one by Bourgouin et al, in which MWA and CA were used [ 33 ]. A relatively wide range of survival rates was demonstrated; the 1- and 3-year OS rates were 81–100% and 47–85%, respectively [ 12 , 33 – 36 ].…”

Section: Introductionmentioning

confidence: 99%

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Up-to-date evidence on image-guided thermal ablation for metastatic lung tumors: a review

et al. 2022

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The aim of this review was to summarize the latest evidence on image-guided thermal ablation therapies for lung metastases. PubMed was used to search for relevant articles that reported the oncological outcomes of thermal ablation for metastatic lung tumors, and those published in 2010 or later were selected for review. Ablative therapies were applied for lung metastases from various types of primary tumors, but most commonly colorectal ones. Radiofrequency ablation (RFA) was the most evaluated technique, followed by microwave ablation (MWA). The local control rates of ablative therapies were generally favorable, approximately 80–90% in many studies. Representative studies demonstrated promising overall survival rates of approximately 50% or higher 5 years after ablation for lung metastases from colorectal cancer or mixed types of primary tumors. Nevertheless, the survival outcomes varied depending on the type of primary tumor and background factors of patients such as other metastases and comorbidities. Several studies had aimed to compare the outcomes of various ablative therapies such as RFA, MWA, and cryoablation; however, conclusive data are not yet available to determine the most appropriate ablation modality for lung metastases. Further data accumulation is needed, especially for long-term outcomes and comparisons with other therapies.

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“…Therefore, CT is commonly used to guide percutaneous thoracic needle biopsies and thermal ablations. [2][3][4][5][6] Reasons to consider guidance with MR instead of CT include limiting ionizing radiation, especially for children and young adults. In the helical mode, reported median radiation exposure of CT-guided thoracic needle biopsies and thermal ablations amount to dose length products of 569 and 1446 mGy×cm, respectively.…”

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confidence: 99%

Magnetic Resonance Imaging for Guidance and Follow-up of Thoracic Needle Biopsies and Thermal Ablations

Kashani

Campbell-Washburn

Murphy

et al. 2022

Journal of Thoracic Imaging

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Magnetic resonance imaging (MRI) is used for the guidance and follow-up of percutaneous minimally invasive interventions in many body parts. In the thorax, computed tomography (CT) is currently the most used imaging modality for the guidance and follow-up of needle biopsies and thermal ablations. Compared with CT, MRI provides excellent soft tissue contrast, lacks ionizing radiation, and allows functional imaging. The role of MRI is limited in the thorax due to the low hydrogen proton density and many air-tissue interfaces of the lung, as well as respiratory and cardiac motion. Here, we review the current experience of MR-guided thoracic needle biopsies and of MR-guided thermal ablations targeting lesions in the lung, mediastinum, and the chest wall. We provide an overview of MR-compatible biopsy needles and ablation devices. We detail relevant MRI sequences and their relative advantages and disadvantages for procedural guidance, assessment of complications, and long-term follow-up. We compare the advantages and disadvantages of CT and MR for thoracic interventions and identify areas in need of improvement and additional research.

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Comparison of Percutaneous Image-Guided Microwave Ablation and Cryoablation for Sarcoma Lung Metastases: A 10-Year Experience

Cited by 23 publications

References 46 publications

Local ablation of pulmonary malignancies abutting pleura: Evaluation of midterm local efficacy and safety

Local ablation of pulmonary malignancies abutting pleura: Evaluation of midterm local efficacy and safety

Up-to-date evidence on image-guided thermal ablation for metastatic lung tumors: a review

Magnetic Resonance Imaging for Guidance and Follow-up of Thoracic Needle Biopsies and Thermal Ablations

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