Comparison of Periodontal Parameters and Self‐Perceived Oral Symptoms Among Cigarette Smokers, Individuals Vaping Electronic Cigarettes, and Never‐Smokers

Javed, Fawad; Abduljabbar, Tariq; Vohra, Fahim; Malmström, Hans; Rahman, Irfan; Romanos, Georgios E.

doi:10.1902/jop.2017.170197

Cited by 92 publications

(131 citation statements)

References 26 publications

Supporting

Mentioning

122

Contrasting

Unclassified

Order By: Relevance

“…The findings of the present study show that the levels of soft and hard tissue damaging proinflammatory cytokines (MMP‐9 and IL‐1β) were significantly higher among individuals in CS and vaping individuals compared with NS. One explanation in this regard is that nicotine in tobacco increases the levels of AGEs in oral tissues including gingival and periodontal tissues . Augmented interfaces between AGEs and their receptors (RAGEs) have been associated with the formation of ROS that induce a state of oxidative burst within gingival tissues, reduced chemotactic, and phagocytic function of polymorphonuclear cells, decrease production of antibodies, thereby increasing bacterial adhesion, and systemic and local inflammatory burden through increased expression of cytokines in the serum and crevicular fluid .…”

Section: Discussionmentioning

confidence: 99%

“…reported that e‐cig aerosols with flavoring agents may have a negative impact on oral epithelial cells and gingival fibroblasts through DNA damage and elevated expression of proinflammatory cytokines such as cyclooxygenase (COX)‐2 and prostaglandin E2 (PGE 2 ). Furthermore, a recent cross‐sectional pilot study by Javed et al . demonstrated statistically higher periodontal inflammation among CS and individuals vaping e‐cigs as compared with never smokers.…”

Section: Introductionmentioning

confidence: 94%

“…From the dental health perspective, vaping has been associated with several oral disorders including submucous fibrosis and periodontal diseases . A laboratory investigation by Sundar et al .…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Proinflammatory cytokine levels and peri‐implant parameters among cigarette smokers, individuals vaping electronic cigarettes, and non‐smokers

ArRejaie

Al‐Aali

Alrabiah

et al. 2018

Journal of Periodontology

Self Cite

108

View full text Add to dashboard Cite

Background Tobacco smoking compromises the prognosis of dental implant treatment and is associated with increased risk of peri‐implant bone loss and increased implant failure rate. There is a dearth of studies that have compared clinical, radiographic, and immunological peri‐implant parameters among cigarette smokers (CS), individuals vaping e‐cigarettes (e‐cigs), and non‐smokers (NS). This study aimed to compare clinical and radiographic peri‐implant parameters and levels of matrix metalloproteinase (MMP)‐9 and interleukin (IL)‐1β levels among CS, individuals’ vaping e‐cigs, and NS. Methods Thirty‐two CS (group 1), 31 individuals vaping e‐cigs (group 2), and 32 NS (group 3) were included. Demographic‐ and implant‐related data were collected using a structured baseline questionnaire. Peri‐implant plaque index (PI), bleeding on probing (BOP), and probing depth (PD) were recorded and marginal bone loss (MBL) were assessed using standardized digital radiographs. Enzyme‐linked immunosorbent assay was used to assess levels of MMP‐9 and IL‐1β in peri‐implant sulcular fluid. Pearson correlation coefficient was used to analyze for correlations of MMP‐9 and IL‐1β levels with peri‐implant parameters. Results BOP showed significantly higher values in group 3 as compared with groups 1 and 2 (P < 0.01). PI (P < 0.01), PD ≥ 4 mm (P < 0.01), and mean concentrations of MMP‐9 (P < 0.001) and IL‐1β (P < 0.01) were significantly higher in groups 1 and 2 than group 3. MBL was significantly higher in group 1 as compared with group 2 and group 3 (P < 0.01). Significant positive correlations were found between MMP‐9 (P = 0.0198) and IL‐1β (P = 0.0047) levels and MBL in group 1; and a significant positive correlation between IL‐1β and MBL in group 2 (P = 0.0031). Conclusions Peri‐implant health was compromised among CS than vaping individuals and NS. Increased levels of proinflammatory cytokines in CS and vaping individuals may suggest greater peri‐implant inflammatory response.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 94%

See 1 more Smart Citation

Proinflammatory cytokine levels and peri‐implant parameters among cigarette smokers, individuals vaping electronic cigarettes, and non‐smokers

ArRejaie

Al‐Aali

Alrabiah

et al. 2018

Journal of Periodontology

Self Cite

108

View full text Add to dashboard Cite

show abstract

“…This hypothesis was based results from previous clinical studies in which, oral soft tissue inflammation and alveolar bone loss (ABL) around natural teeth and dental implants was shown to be significantly higher among CS compared with NS. 7,16,19,20 Moreover, tobacco smoking increases the AGES-RAGE interactions thereby increasing the production of destructive inflammatory cytokines, such as IL-6 and IL-1b. 10,11 Increased levels of these cytokines in the oral fluids have been associated with the etiology of periodontal and peri-implant diseases.…”

Section: Discussionmentioning

confidence: 99%

Comparison of peri‐implant clinical and radiographic status around short (6 mm in length) dental implants placed in cigarette‐smokers and never‐smokers: Six‐year follow‐up results

Abduljabbar

Al-Hamoudi

Al-Sowygh

et al. 2017

Clin Implant Dent Rel Res

Self Cite

View full text Add to dashboard Cite

Background: It is hypothesized that peri-implant clinical and radiographic inflammatory parameters (probing depth [PD], bleeding on probing [BOP] and plaque index [PI]; and radiographic (crestal bone loss [CBL]) are worse among cigarette-smokers (CS) compared with never-smokers (NS) with short implants.Purpose: The present 6-year follow-up retrospective study compared the peri-implant clinical and radiographic parameters in CS and NS with short dental implants (6 mm in length). Materials and methods:Fifty-six male individuals were included. These individuals divided into 2 groups as follows: (a) Group-1: 29 self-reported systemically healthy CS with 48 short-implants; and (b) Group-2: 27 self-reported systemically healthy NS with 43 short implants. Peri-implant PD, PI, BOP, and CBL were measured. Group comparisons were done using the Kruskal-Wallis test and sample size was estimated. Level of significance was set at P values < .05. Results:In groups 1 and 2, the follow-up durations were 6.2 6 0.1 years and 6.1 6 0.3 years, respectively. A cigarette smoking history of 8.9 6 3.6 pack years was reported by individuals in Group-1. At follow-up, scores of peri-implant PD, BOP, PI, and mesial and distal CBL were comparable around short implants in both groups. Conclusion:Under strict oral hygiene maintenance protocols, short dental implants can remain functionally stable in CS in a manner similar to NS.

show abstract

“…To the Editor: We read with interest the pilot study by Javed et al . comparing periodontal parameters in cigarette smokers, electronic cigarette (e‐cigarette) users, and never‐smokers.…”

mentioning

confidence: 99%

Letter to the editor: RE: Comparison of periodontal parameters and self‐perceived oral symptoms among cigarette smokers, individuals vaping electronic cigarettes and never‐smokers: A pilot study

Holliday

Ryan

McColl

et al. 2018

Journal of Periodontology

View full text Add to dashboard Cite

Comparison of Periodontal Parameters and Self‐Perceived Oral Symptoms Among Cigarette Smokers, Individuals Vaping Electronic Cigarettes, and Never‐Smokers

Abstract: Periodontal inflammation and self-perceived OSs were poorer among CSs than among vaping individuals and NSs.

Cited by 92 publications

References 26 publications

Proinflammatory cytokine levels and peri‐implant parameters among cigarette smokers, individuals vaping electronic cigarettes, and non‐smokers

Proinflammatory cytokine levels and peri‐implant parameters among cigarette smokers, individuals vaping electronic cigarettes, and non‐smokers

Comparison of peri‐implant clinical and radiographic status around short (6 mm in length) dental implants placed in cigarette‐smokers and never‐smokers: Six‐year follow‐up results

Letter to the editor: RE: Comparison of periodontal parameters and self‐perceived oral symptoms among cigarette smokers, individuals vaping electronic cigarettes and never‐smokers: A pilot study

Contact Info

Product

Resources

About