Comparison Of Physical Activity And Sedentary Behavior In Autologous And Allogeneic Hematopoietic Stem Cell Transplantation Survivors

Abstract

Purpose: The treatment background, as well as the frequency and type of complications, in autologous (auto-) and allogeneic (allo-) hematopoietic stem cell transplantation (HSCT) survivors influence the appearance of moderate to vigorous physical activity (MVPA) or sedentary behavior. We aimed to identify differences in MVPA and sedentary behavior between auto- and allo-HSCT survivors. Methods: We included 13 auto- and 36 allo-HSCT survivors (≈ 4 years after HSCT). MVPA and sedentary behavior were assessed using a triaxial accelerometer.Results: There were no significant between-group differences in MVPA and sedentary behavior (p = 0.768 and 0.739, respectively). In allo-HSCT survivors, MVPA was negatively correlated with the Hospital Anxiety and Depression Scale score (r = -0.358, p = 0.032). Stepwise multiple regression analysis showed that age was a significant predictor of sedentary behavior in allo-HSCT survivors (β = 0.400, p = 0.016). Conclusion: We observed no significant between-group differences in MVPA and sedentary behavior. Our results suggest that it may be unnecessary to change the rehabilitation program according to the donor type in interventions for promoting MVPA and reducing sedentary behavior in long-term HSCT survivors.