Comparison of psychiatric morbidity in patients with irritable bowel syndrome and non-ulcer dyspepsia

Padhy, Susanta Kumar; Mishra, Surbhi; Sarkar, Siddharth; Bang, Late Govind; Panigrahi, Mahima

doi:10.4103/0972-6748.196038

Cited by 9 publications

(6 citation statements)

References 26 publications

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“…The most prominent psycho social trait in functional dyspepsia is psychiatric comorbidity. An increased prevalence of anxiety, depression, somatization and high neuroticism is well documented in patients with functional dyspepsia compared with healthy cohorts but could also be higher compared with patients with organic gastrointestinal or nongastrointestinal disease 120,121,122 ; comparison with patients with IBS remains inconclusive. Some evidence supports a higher prevalence of physical and emotional abuse, life event-related stress and dysfunctional coping styles in patients with functional dyspepsia compared with healthy controls 120 .…”

Section: Psychosocial Factors and Brain Mechanismsmentioning

confidence: 99%

Functional dyspepsia

Enck¹,

Azpiroz

Boeckxstaens

et al. 2017

Nat Rev Dis Primers

260

247

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| Functional dyspepsia is one of the most prevalent functional gastrointestinal disorders. Functional dyspepsia comprises three subtypes with presumed different pathophysiology and aetiology: postprandial distress syndrome (PDS), epigastric pain syndrome (EPS) and a subtype with overlapping PDS and EPS features. Functional dyspepsia symptoms can be caused by disturbed gastric motility (for example, inadequate fundic accommodation or delayed gastric emptying), gastric sensation (for example, sensations associated with hypersensitivity to gas and bloating) or gastric and duodenal inflammation. A genetic predisposition is probable but less evident than in other functional gastrointestinal disorders, such as irritable bowel syndrome (IBS). Psychiatric comorbidity and psychopathological state and trait characteristics could also play a part, although they are not specific to functional dyspepsia and are less pronounced than in IBS. Possible differential diagnoses include Helicobacter pylori infection and peptic ulceration. Pharmacological therapy is mostly based on the subtype of functional dyspepsia, such as prokinetic and fundus-relaxing drugs for PDS and acid-suppressive drugs for EPS, whereas centrally active neuromodulators and herbal drugs play a minor part. Psychotherapy is effective only in a small subset of patients, whereas quality of life can be severely affected in nearly all patients. Future therapies might include novel compounds that attempt to treat the underlying gastric and duodenal inflammation. NATURE REVIEWS | DISEASE PRIMERS VOLUME 3 | ARTICLE NUMBER 17081 | 1 PRIMER © 2 0 1 7 M a c m i l l a n P u b l i s h e r s L i m i t e d , p a r t o f S p r i n g e r N a t u r e . A l l r i g h t s r e s e r v e d .standard therapy for gastro -oesophageal reflux disease. Paediatric dyspeptic symptoms are being addressed in a separate classification effort 10 . This Primer covers functional dyspepsia in adults only, although we sporadically refer to paediatric functional dyspepsia when similarities exist. EpidemiologyThe population prevalence of functional dyspepsia is quite variable across the globe, with overall high numbers (10-40%) in Western countries and low numbers (5-30%) in Asia, independent of the respective functional dyspepsia definitions 11 . A large-scale health and nutrition survey from France 12 (which involved >35,000 people) identified that 15% of individuals had suspected functional dyspepsia, 28% had irritable bowel syndrome (IBS) and 6% had both. The population of patients who are affected by both IBS and functional dyspepsia has been reported to range between 10% and 27% in previous studies 13 and to approach 30% in popu lation samples; it could be even higher in specific populations 14,15 . This observation has given rise to the term 'overlap syndrome' (REF. 13), which calls into question the sensitivity and specificity of the Rome criteria, at least for IBS and functional dyspepsia. This argument is also supported by the observation that patients with functional dyspepsia m...

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Section: Psychosocial Factors and Brain Mechanismsmentioning

confidence: 99%

Functional dyspepsia

Enck¹,

Azpiroz

Boeckxstaens

et al. 2017

Nat Rev Dis Primers

260

247

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“…It is, however, not used for delirious, mentally retarded, or frankly psychotic patients. [13][14][15]. Informed written consent was taken from all the participants for voluntary participation in the local language (Hindi & Chhattisgarhi).…”

Section: Study Toolmentioning

confidence: 99%

analytical study of psychiatric complains in intensive care unit patients

Dutta¹,

Wasnik²,

Bijali³

2022

ijhs

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Introduction: Numerous studies have established a higher incidence of psychiatric disorders among general hospital inpatients. In our local / Indian set ups there is a lack of literature on the prevalence of psychiatric morbidity in patients admitted to the intensive care units. Hence this study was conducted to find psychiatric morbidity among the patients of the intensive care unit (ICU). Methods: The present Observational, Analytical & Cross-Sectional study is carried out on 100 subjects. The SCL-R-90 scale was administered to the participants by the faculty in their respective colloquial language. Each item of the questionnaire is rated by the patient on a five-point Likert scale of distress ranging from 0 (none) to 4 (extreme). Results: Nearly 49% of the participants had no psychiatric morbidity. 36% had mild and 15% had moderate psychiatric morbidity as per the SCL-90-R Scale. There was no participant with severe psychiatric morbidity. Factors such as age, gender, educational level, or duration of stay had no significant influence on the outcome. Among the psychiatric manifestations, interpersonal sensitivity and somatization were found to be the most prevalent symptoms.

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“…При этом, рассматриваемое психосоматическое расстройство, по видимому, реализовано по оси «головной мозг -кишечник -головной мозг» [28]. В обзоре S. K. Padhy также отмечается необходимость направленного терапевтического воздействия как на соматические, так и на психоэмоциональные звенья СРК [29].…”

Section: обзор исследований и обсуждениеunclassified

Irritable bowel syndrome: clinical, psychological and psychosocial interdependence

Барановский

Вассерман

Fedorová

et al. 2019

jour

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The article presents the results of the authors’ own observations and an overview of the main directions in clinical and experimental psychological studies of patients with irritable bowel syndrome (IBS), which includes complementary data in the framework of the modern biopsychosocial paradigm and the concept of psychosomatic relationships. The analysis confirms the complex somatocentric basis of the idea of the disease in patients using cognitively determined separation of physiological (bodily) and psychosocial determinants, which can be considered as a vector for psychotherapeutic interventions and secondary psychoprophylaxis. It is emphasized that the attitude to the disease as a socially frustrating factor has a stronger effect on the quality of life of patients and adaptive potential than the actual symptoms of the disease.

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Comparison of psychiatric morbidity in patients with irritable bowel syndrome and non-ulcer dyspepsia

Cited by 9 publications

References 26 publications

Functional dyspepsia

Functional dyspepsia

analytical study of psychiatric complains in intensive care unit patients

Irritable bowel syndrome: clinical, psychological and psychosocial interdependence

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