Comparison of ropivacaine and bupivacaine for intrathecal anesthesia during outpatient arthroscopic surgery

Boztuğ, N.; Bıgat, Zekiye; Karslı, Bilge; Saykal, N.; Ertok, Ertugrul

doi:10.1016/j.jclinane.2006.03.006

Cited by 31 publications

(28 citation statements)

References 31 publications

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“…Our findings were in affirmation with the study of Chan Jong Chungar et al, where motor blockade with hyperbaric ropivacaine 18 mg was 113.7 min compared to 158.7 min with hyperbaric bupivacaine 12 mg. 6 Boztug et al observed complete motor blockade in 88% of patients receiving ropivacaine and 100% patients receiving bupivacaine when administered for knee arthroscopy. 7 In our study both the groups developed complete motor block, albeit a slower onset in ropivacaine group.…”

Section: Comparison Of Motor Effectssupporting

confidence: 54%

A Study of Hyperbaric Bupivacaine Versus Isobaric Ropivacaine for Elective Caesarean Deliveries

Konda¹,

Anpuram²,

Chakravarthy³

2016

jemds

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OBJECTIVEIs to compare the anaesthetic effects of intrathecal administration of hyperbaric Bupivacaine 10 mg with isobaric Ropivacaine 15 mg for elective caesarean delivery. METHOD100 parturients of ASA 1 and II posted for elective caesarean delivery were randomly divided into 2 groups of 50 each: Group A received intrathecal 0.5% Hyperbaric Bupivacaine 10 mg and Group B received intrathecal 0.75% isobaric Ropivacaine 15 mg. Time of onset and regression of sensory and motor blocks, haemodynamics, time of first complaint of pain, neonatal APGAR and side-effects were evaluated. RESULTSRopivacaine group has significantly slower onset of sensory analgesia at T6 (4.45±0.03 in Ropivacaine group as against 2.38±0.36 in Bupivacaine group, p <0.05), slower onset of Grade 3 motor block (6.46±2.48 in Ropivacaine group, 3.06±0.9 in Bupivacaine group p <0.05) and shorter duration of motor block (102.50±11.09 in Ropivacaine group as against 120.30±11.10 in Bupivacaine group p <0.05). Faster regression of the block to L1 and S2 was noticed in Ropivacaine group. (Regression to L1 122.6±20.5 in Ropivacaine and 144.10±28.19 in Bupivacaine group, p <0.05; Complete sensory regression to S1 150.0±14.8 in Ropivacaine and 169.6±20.4 in Bupivacaine group; p <0.05). Time to first complaint of pain was comparable in both the groups (168.9±26.0 in Ropivacaine and 170.2±25.5 in Bupivacaine group p >0.05). There was no difference in the haemodynamics and neonatal APGAR. Neither of the groups had any significant intraoperative or postoperative complications. CONCLUSIONIntrathecal Isobaric Ropivacaine 15 mg provides effective spinal anaesthesia for caesarean delivery. It has slower onset, shorter motor block, early sensory regression and similar postoperative analgesia and APGAR scores as compared to 10 mg of 0.5% hyperbaric bupivacaine. The shorter duration of motor block can facilitate early ambulation and makes Ropivacaine a good alternative for elective caesarean deliveries. KEYWORDSRopivacaine, Bupivacaine, Anaesthesia, Caesarean Deliveries. HOW TO CITE THIS ARTICLE:Konda RRM, Anpuram LN, Chakravarthy K. A study of hyperbaric bupivacaine versus isobaric ropivacaine for elective caesarean deliveries.

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Section: Comparison Of Motor Effectssupporting

confidence: 54%

A Study of Hyperbaric Bupivacaine Versus Isobaric Ropivacaine for Elective Caesarean Deliveries

Konda¹,

Anpuram²,

Chakravarthy³

2016

jemds

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“…Recent studies, comparing Ropivacaine with Bupivacaine, found that epidural Ropivacaine produces a blockade which is substantially similar to that produced by equivalent concentrations and doses of Bupivacaine. [1112]…”

Section: Discussionmentioning

confidence: 99%

Hemiarthroplasty in high risk elderly patient under epidural anesthesia with 0.75% ropivacaine-fentanyl versus 0.5% bupivacaine-fentanyl: Clinical trial

et al. 2013

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Background:Anesthetic management of elderly patients is a challenge as aging makes them more susceptible to hemodynamic fluctuations during regional anesthesia. This study was aimed to compare the clinical efficacy of epidural 0.75% ropivacaine fentanyl (RF)– with 0.5% bupivacaine–fentanyl (BF) for hemiarthroplasty in high-risk elderly patients.Methods:Sixty elderly consented patients of either sex with American Society of Anesthesiologist ASA II and III, scheduled for elective hemiarthroplasty were randomized into two Groups of 30 patients to receive epidural study solution of 15 mL of 0.75% Ropivacaine or 0.5% Bupivacaine with 1 mL fentanyl (50 μg). The hemodynamic variability with onset and duration of sensory and motor blocks were recorded. The adequacy and quality of surgical anesthesia were assessed. The post-epidural nausea and vomiting, shivering, respiratory parameters, or any other side effects were also recorded.Results:There was no difference in the demographic profile between groups. The mean onset time to achieve sensory block to the T10 dermatome was rapid in the Group BF (12.4±6.9 vs. 17.5±3.7 min in Group RF). The mean time to achieve motor block was 17.5±3.4 min in Group BF versus 21.7±7.8 min in Group RF. The intraoperative hemodynamic fluctuations showed statistically significant differences between groups. The pruritis was observed in five patients but post-epidural shivering, nausea, vomiting, respiratory depression, or urinary retention were not observed in any patient.Conclusion:Epidural 0.75% Ropivacaine with fentanyl showed better clinical profile as compared to 0.5% Bupivacaine with fentanyl for hemiarthroplasty in elderly patients.

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“…Ropivacaine could provide adequate surgical anesthesia without compromising early ambulation and discharge. [4567]…”

Section: Introductionmentioning

confidence: 99%

Ropivacaine: Anesthetic consideration in elderly patients for transurethral resection of prostrate a clinical trial

et al. 2013

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Background:Ropivacaine has less systemic toxicity and greater differentiation of sensory and motor blockade after subarachnoid block. This study was aimed to evaluate the anesthetic efficacy of intrathecal 0.75% isobaric ropivacaine alone or with fentanyl in elderly patients undergoing transurethral resection of prostrate.Materials and Methods:Fifty four elderly consented patients of ASA grade I-III scheduled for transurethral resection of prostrate under the subarachnoid block were randomized to receive either intrathecal 4 mL of 0.75% isobaric ropivacaine (Group R, n = 27) or 3.5 mL of 0.75% isobaric ropivacaine with 0.5 mL (25 μg) of fentanyl (Group RF, n = 27). The characteristics of sensory and motor blockade, intraoperative hemodynamic changes, and secondary effects were noted for evaluation.Results:There was no significant difference in the demographic profile of patients. The surgical anesthesia was adequate for TURP surgery in all patients. The median time to achieve the sensory blockade at T10 dermatome was 3.2 ± 1.5 min in Group R and 3.5 ± 1.3 min in Group RF. The median duration of sensory blockade at T10 was 130.6 ± 10.2 min in Group R and 175.8 ± 8.6 min in Group RF. The median duration of complete motor block was significantly shorter than the duration of sensory blockade (P < 0.001). There were fewer episodes of manageable hypotension in 5 patients of Group R and 11 patients of Group RF. No secondary effects have occurred in any patients.Conclusion:The intrathecal 0.75% isobaric ropivacaine alone or with fentanyl has provided effective surgical anesthesia for transurethral resection of prostrate and hemodynamic stability in elderly patients.

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Comparison of ropivacaine and bupivacaine for intrathecal anesthesia during outpatient arthroscopic surgery

Cited by 31 publications

References 31 publications

A Study of Hyperbaric Bupivacaine Versus Isobaric Ropivacaine for Elective Caesarean Deliveries

A Study of Hyperbaric Bupivacaine Versus Isobaric Ropivacaine for Elective Caesarean Deliveries

Hemiarthroplasty in high risk elderly patient under epidural anesthesia with 0.75% ropivacaine-fentanyl versus 0.5% bupivacaine-fentanyl: Clinical trial

Ropivacaine: Anesthetic consideration in elderly patients for transurethral resection of prostrate a clinical trial

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