Comparison of salvage and planned pharyngolaryngectomy with jejunal transfer for hypopharyngeal carcinoma after chemoradiotherapy

Abstract

Salvage pharyngolaryngectomy and jejunal transfer can be performed safely and reliably for patients with locally recurrent hypopharyngeal carcinoma, and it is an excellent option after a failure of definitive chemoradiotherapy.

Free jejunal flap transfer with multiple vascular pedicles for safe and reliable pharyngoesophageal reconstruction

“…In addition, the thick mesentery can provide good coverage to support skin grafting in cases in which primary closure of neck skin is not possible (see Figure 4). 6,7,[22][23][24][26][27][28] Good swallowing function was achieved in our series. With respect to fistula formation, the rates of occurrence according to previous reports were 0%-30%, 6,7,22-28 as compared with 3.7% in our cases.…”

Outcomes of Anterolateral Thigh Flap Reconstruction for Salvage Laryngopharyngectomy for Hypopharyngeal Cancer after Concurrent Chemoradiotherapy

“…Kadota et al reported the results of an analysis on 14 patients who underwent salvage surgery after definitive chemoradiotherapy in a single-institution study. The 5-year disease-free survival and local control rates were 57.1% and 92.9%, respectively [20]. However, less favorable results have also been reported.…”

Fasciocutaneous free flaps for reconstruction of hypopharyngeal defects

“…Currently, fasciocutaneous free flaps, in particular radial forearm (RF) and anterolateral thigh (ALT), are considered among the main options for such a reconstructive purpose, especially considering the high rates of PCF and stenosis generally observed after pectoralis major myocutaneous (PMMC) pedicled flap, and the non‐negligible complication rate associated with a jejunum free flap …”