Comparison of Sleep Disorders between Real and Simulated 3,450-m Altitude

Abstract

Our results suggest that HH has a greater effect on nocturnal breathing and sleep structure than NH. In HH, we observed more periodic breathing, which might arise from the lower saturation due to hypobaria, but needs to be confirmed.

CrossTalk proposal: Barometric pressure, independent of , is the forgotten parameter in altitude physiology and mountain medicine

“…) and during sleep (Heinzer et al . ; Saugy et al . ). HH has been associated with greater sleep quality disturbance (Heinzer et al .…”

“…). HH has been associated with greater sleep quality disturbance (Heinzer et al . ; Saugy et al . ). HH elicits higher systemic oxidative stress (Faiss et al .…”

CrossTalk opposing view: Barometric pressure, independent of , is not the forgotten parameter in altitude physiology and mountain medicine

“…For example, Heinzer and Rupp use a of 13.6% to simulate an altitude of 3450 m, which is too high (Table ) and may perfectly explain why they found a greater effect of hypobaric than of normobaric hypoxia (Heinzer et al . ; Rupp et al . ).…”

Case studies in physiology: Nocturnal cardiorespiratory adaptive differences between an Italian trekker and a Nepali guide

“…In contrast, the Italian trekker's breathing rate, normalized for non‐apneic sleep, decreased at HA; a trend that would have been masked by a lack of data normalization. The pattern of sleep in the Italian, with the presence of apneic episodes at HA, a likely adaptive feature of sleep‐breathing function, deserves further exploratory research, particularly in the face of a report by Heinzer et al showing the lack of breathing rate adaptation in response to hypobaric hypoxia (Heinzer et al., 2016). We suggest that a decrease in body weight that we noticed in the trekkers mass could affect the respiratory system, which entails an intertwined function (Homma & Masaoka, 2008; Littleton, 2012; Salome, King, & Berend, 2010; Thomas, Cowen, Hulands, & Milledge, 1989).…”