Comparison of the Clinical Outcomes of Buccal Advancement Flap Versus Platelet-Rich Fibrin Application for the Immediate Closure of Acute Oroantral Communications

Bilginaylar, Kani

doi:10.1097/scs.0000000000004958

Cited by 9 publications

(14 citation statements)

References 16 publications

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“…The ndings reported also con rm the hypothesis of signi cant differences with regard to the presence of pain and the use of painkillers taken between the two groups. This is consistent with the ndings of Bilginaylar using platelet-rich brin for oroantral communication closure and may either be attributed to the less invasive treatment protocol or to the anti-in ammatory activity and immune regulation effects of the platelet-rich brin content [15]. Pain reduction was also reported in separate clinical studies of…”

Section: Discussionsupporting

confidence: 88%

“…However, although the ndings of the present study as well as the results of the previous studies of Blingalar, Gülesen and Agarwallse have indicated high success rates, there is controversial information about the number and the form of PRF clots to be used [15,23,24]. The smallest numbers of platelet-rich brin clots were used by Biligalyr using only two platelet-rich brin clots pressed into plugs [15]. In obvious contrast, the largest number of 6 clots was used by Gülden who also reported a successful healing process [23].…”

Section: Discussioncontrasting

confidence: 49%

“…Different autogenous methods for closure of oroantral communications according to Parvini et al [4] Recently, considerations of alternative treatment modalities have included the successful use of plasmarich brin (PRF) for OAC as reported by Demetoglu et al [12], Assad et al [13] and Bilginalyar [14] in separate studies. In a sophisticated randomized evaluation by Bilginaylar [15] the clinical outcome of OAC closure was compared for the use of PRF and buccal advancement ap revealing successful outcome for both methods with a reduction of pain and swelling with the use of PRF.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Platelet-rich fibrin vs. local buccal advancement flap for closure of oroantral communications: A prospective clinical study

Hunger

Krennmair

et al. 2022

Preprint

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Objectives This study compared the clinical outcome as well as the wound healing course, the displacement of the mucogingival border (MGB) and the pain level between the use of platelet-rich fibrin (PRF) and buccal advancement flap (BAF) for the closure of oroantral communications (OAC). Material and Methods Fifty eligible patients with an OAC defect larger than 3 mm were randomly assigned either to PRF (test group, n = 25) or BAF (control group, n = 25) for defect closure. In a prospective follow-up program the defect closure healing process, the scoring of the wound healing course by Landry wound healing index (score: 0–5) as well as the displacement of the MGB and the postoperative pain score were evaluated. Results Five patients in each group were lost to follow-up resulting in 40 patients (20 in each group) for continuous evaluation. At postoperative day 21 (study endpoint) a non-significant difference regarding success rate (defined as closure of OAC) was noticed between the test (90%; 18/20) and control group (90%; 18/20). A univariate analysis showed significant differences for age and defect size/height for the use of PRF between successful-tight and open–failed defect healing. At the final evaluation, a significant (p = 0.005) better wound healing score, a lower displacement of the MGB as well as lower pain-score were seen for the use of PRF. Conclusions PRF is promising regarding defect healing outcome. Clinical relevance The defect size should be taken into account when choosing the number and size of PRF plugs used.

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Section: Discussionsupporting

confidence: 88%

Section: Discussioncontrasting

confidence: 49%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Platelet-rich fibrin vs. local buccal advancement flap for closure of oroantral communications: A prospective clinical study

Hunger

Krennmair

et al. 2022

Preprint

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“…36 In the settings of oroantral communication, a previous study reported that the administration of PRP was significantly associated with pain relief and reduced swelling, in addition to accelerated wound healing when compared to the outcomes of buccal advancement flap. 37 Demetoglu et al furtherly reported that in cases of oroantral communication (≤5 mm), a platelet-rich fibrin membrane can be used to manage these cases. 38 Osteoradionecrosis of the jaw was also previously reported to be effectively managed by the administration of PRP.…”

Section: Efficacy Of Prp In the Different Maxillofacial Surgeriesmentioning

confidence: 99%

Role of platelet-rich plasma in maxillofacial surgery

Hifny

Alalharith

Idrees³

et al. 2021

Int J Community Med Public Health

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Platelet-rich plasma (PRP) has been reported as an efficacious modality that can enhance the process of wound healing and tissue regeneration and has been validated in different medical settings, including cardiovascular surgery, otolaryngology, head and neck surgery, and maxillofacial surgery. In dental and oral surgery settings, PRP has been reported as an efficacious approach with favorable outcomes in different settings. Some of these procedures include surgical repair of the alveolar cleft, mandibular reconstruction, ablative surgical procedures, placement of osseointegrated implants, periodontal plastic surgery, and management of infrabony periodontal defects. In the present study, we aim to discuss the role and mechanisms that PRP plays in the settings of maxillofacial surgery based on evidence from the relevant studies in the literature. Evidence indicates the wide acceptance of the modality, which has been proven to increase the rate of wound healing and reduce the frequency of pain and swelling. The administration of PRP has been reported to dispense with the need for invasive approaches that might be furtherly associated with complications and different morbidities. However, in most of the favorable events where the PRP administration of was associated with enhanced outcomes, the modality was used in combination with another therapeutic approach. Therefore, further research is needed to validate the efficacy of the modality in the different settings.

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“…The treatment of OAC depends on the size of the communication and it is usually achieved by buccal advancement flaps. PRF clots enhance wound closure and reduce pain and swelling compared to buccal advancement flap (104). In addition, PRF membrane could be used to manage OAC of size ≤ 5 mm (105).…”

Section: Regenerative Properties Of Platelet Granulesmentioning

confidence: 99%

Regenerative Effect of Platelet Concentrates in Oral and Craniofacial Regeneration

Al-Hamed

Mahri

Al-Waeli

et al. 2019

Front. Cardiovasc. Med.

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Platelet concentrates (PCs) are biological autologous products derived from the patient's whole blood and consist mainly of supraphysiologic concentration of platelets and growth factors (GFs). These GFs have anti-inflammatory and healing enhancing properties. Overall, PCs seem to enhance bone and soft tissue healing in alveolar ridge augmentation, periodontal surgery, socket preservation, implant surgery, endodontic regeneration, sinus augmentation, bisphosphonate related osteonecrosis of the jaw (BRONJ), osteoradionecrosis, closure of oroantral communication (OAC), and oral ulcers. On the other hand, no effect was reported for gingival recession and guided tissue regeneration (GTR) procedures. Also, PCs could reduce pain and inflammatory complications in temporomandibular disorders (TMDs), oral ulcers, and extraction sockets. However, these effects have been clinically inconsistent across the literature. Differences in study designs and types of PCs used with variable concentration of platelets, GFs, and leucocytes, as well as different application forms and techniques could explain these contradictory results. This study aims to review the clinical applications of PCs in oral and craniofacial tissue regeneration and the role of their molecular components in tissue healing.

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Comparison of the Clinical Outcomes of Buccal Advancement Flap Versus Platelet-Rich Fibrin Application for the Immediate Closure of Acute Oroantral Communications

Cited by 9 publications

References 16 publications

Platelet-rich fibrin vs. local buccal advancement flap for closure of oroantral communications: A prospective clinical study

Platelet-rich fibrin vs. local buccal advancement flap for closure of oroantral communications: A prospective clinical study

Role of platelet-rich plasma in maxillofacial surgery

Regenerative Effect of Platelet Concentrates in Oral and Craniofacial Regeneration

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