Comparison of the effects of laser and ultrasound treatments on experimental wound healing in rats

Abstract

-A randomized controlled study investigated the effects of ultrasound and laser treatments on wound healing in rats. The duration of the inflammatory phase decreased with both laser and ultrasound treatments; however, laser was more effec-tive than ultrasound, with more significant results. The prolifera-tion phase showed, for both treatments, an increase in the level of hydroxyproline and the number of fibroblasts, as well as stimula-tion of the collagen synthesis and the composition. Laser treat-ment was again more effective than ultrasound. The wound breaking strength was significantly higher with both treatments, and no statistically significant difference emerged between the laser and ultrasound groups, although laser treatment provided a much greater increase in the wound breaking strength than ultra-sound. Both treatments have beneficial effects on the inflamma-tory, proliferation, and maturation phases of wound healing. Both can be used successfully for decubitis ulcers and chronic wounds, in conjunction with conventional therapies such as debridement and daily wound caring. However, laser treatment was more effective than ultrasound in the first two phases of wound healing.

Effects of Low-Level Laser Therapy and Orthodontic Tooth Movement on Dental Pulps in Rats

“…[11][12][13][14][15][16][17][18] Furthermore, studies in vivo and in vitro have demonstrated that laser increases ATP levels 15 and activates specific enzymes that accelerate tissue healing and repair, neovalcularization, [11][12][13][14][15]18 and increases in leukocyte phagocytic activity. 12,15 In addition, the laser effects are related to attenuation of painful symptoms in the diverse postoperative processes and mucosal lesions. 11,18 Cruz et al 9 demonstrated clinically that LLLT accelerates the orthodontic movement in humans.…”

Comparison of the Effect of Low-Level Laser and Phenytoin Therapy on Skin Wound Healing in Rats

“…[11][12][13] Several methods have been used to study healing promotion, but few studies investigated these modalities in comparison to each other. [14][15][16][17][18] In this study we evaluated the effect of low-level laser in wound healing and compared it with phenytoin.…”

Low-Level Laser Therapy is More Effective Than Pulse Ultrasound Treatment on Wound Healing: Comperative Experimental Study

“…13 Simi larly, in many ot her pub lis hed pa pers this be nefi ci al ef fect was ob ser ved bet we en the 5 th and 10th days. 22,27 Our fin ding is in ag re e ment with Bisht et al and ot hers. In this pe ri od, an gi o ge ne sis was found to be slightly hig her in la ser gro up.…”

“…In a li te ra tu re search, we fo und only one re se arch com pa ring the ef fects of US and LLLT on ex pe ri men tal wo und hea ling. 22 In that study, De mir et al used an in ci si onal wo und mo del in which the 4 th and 10 th days we re ta ken in con si de-ra ti on to in ves ti ga te the histo pat ho lo gi cal chan ges. An gi o ge ne sis was not eva lu a ted in the ir study.…”

“…[13][14][15][16][17][18][19][20][21] In the pre sent li te ra tu re, the com pa ra ti ve data of both tre at ment mo da li ti es con cer ning wo und he a ling is very li mi ted. 22 Mo re o ver, to the best of our know led ge, the re is no da ta that com pa re the two tre at ment mo da li ti es in ex ci si o nal wo und hea ling in terms of both his to pat ho lo gic and bi oc hemi cal chan ges. So that, the pre sent study was de sig ned firstly to in ves ti ga te and se condly to compa re the in di vi du al ef fects of US and LLLT on the wo und he a ling pro cess in terms of mic ros co pic and his to-pat ho lo gi cal eva lu a ti on on the 7 th and 15 th days.…”