Comparison of the efficacy of ethylenediaminetetraacetic acid and tetracycline hydrochloride as root conditioning agents: An in vitro study

Nanda, Tarun; Jain, Sanchit; Kapoor, Daljit; Kaur, Harpreet; Nanda, Sonia

doi:10.4103/2231-0754.131368

Cited by 4 publications

(5 citation statements)

References 23 publications

(42 reference statements)

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“…The mean smear layer removal in the EDTA group in the current study was 2.95 ± 0.88, which is similar to the previous study by Nanda et al ., where the mean smear layer removal was 2.95 ± 0.394. [ 25 ] However, in a previous study employing 15% EDTA, the mean smear layer reduction was 1.36 ± 0.230, which is much less than the current study. [ 26 ] This might be related to the difference in EDTA application technique, since the current study utilized active burnishing for 3 min, while Jalaluddin et al .…”

Section: Discussioncontrasting

confidence: 85%

Scanning electron microscopic analysis of 5% glycolic acid as a novel alternative to 17% ethylenediaminetetraacetic acid in root biomodification: An in vitro study

Gottumukkala,

Lakshmi,

Penmetsa

et al. 2024

Journal of Indian Society of Periodontology

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Background: Nonsurgical periodontal therapy results in the formation of a smear layer which inhibits tissue regeneration. Root biomodification (RB) using various agents has been tried for the enhancement of new attachment formation. However, no substantial therapeutic advantages of currently available root conditioning agents have been reported emphasizing the need for additional biologically acceptable agents. Glycolic acid (GA) due to its antimicrobial nature and ability of initiation and proliferation of fibroblasts may potentially modify root surface enabling regeneration. Materials and Methods: Eighty specimens from 40 single-rooted teeth were treated with 17% ethylenediaminetetraacetic acid (EDTA) and 5% GA and scanning electron microscopy analysis was done. The micrographs were examined for the evaluation of smear layer removal, total number of dentinal tubules, total number of patent dentinal tubules, mean diameter and surface area of dentinal tubules, and dentin erosion. Statistical analysis was done using unpaired t-test for intergroup comparison. Results: The efficacy of smear layer removal (P = 0.01) and dentin erosion (P = 0.042) was significantly better in the GA group. Both the groups showed no difference in dentinal tubule-related parameters. Conclusion: GA showed improved RB with greater smear layer removal and lesser dentin erosion, indicating its use as a potent alternative to the conventional EDTA root conditioning.

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Section: Discussioncontrasting

confidence: 85%

Scanning electron microscopic analysis of 5% glycolic acid as a novel alternative to 17% ethylenediaminetetraacetic acid in root biomodification: An in vitro study

Gottumukkala,

Lakshmi,

Penmetsa

et al. 2024

Journal of Indian Society of Periodontology

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“…Tetracyclines are well known broad spectrum antimicrobial in controlling periodontal pathogens. Dentin root surface demineralization by low pH tetracycline increases fibronectin, thus enhances fibroblast attachment and growth while suppressing epithelial cell attachment and growth [11].…”

Section: Resultsmentioning

confidence: 99%

“…These exposed root surfaces have an enlarged dentin tubules, removing toxins from the root surface and preparing a better tissue bed for the healing connective tissue. The demineralization by these agents will cause an increase in total surface area available for the possible binding of extra cellular matrix proteins which play an important role in new attachment and regenerative therapies [11].…”

Section: Resultsmentioning

confidence: 99%

Treatment of root coverage with platelet rich fibrin and coronally advanced flap: A case report

Darjanki¹,

Arief²,

Krismariono³

2022

World J. Adv. Res. Rev.

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Background: Gingival recession was one of disorder that frequently found in periodontal tissue. It is a result in exposed root surface and causing discomfort on patient due to the dentin hypersensitivity. One of various modification of gingival recession treatment is the use of platelet-rich fibrin (PRF) in combined with coronally positioned flap. Objective: The present case aims to describe the effectiveness of coronally advanced flap (CAF) in combined with PRF in root coverage of Miller’s class 1 gingival recession. Case: A 23 years old female patient complains that she feels a slight pain discomfort on her upper right teeth while taking cold beverages. Clinical findings shows that her upper right premolars having a gingival recession, making her root exposed. Case management: Prior the surgery, patient was performed scaling and root planning. Afterward, coronally advanced flap in combined with PRF was done on premolar region to cover the exposed root surface. Results: Clinical observation of three weeks revealed a complete root coverage with an adequate keratinized tissue and good healing. Conclusion: Coronally advanced flap in combination with platelet-rich fibrin provide an effective treatment in root coverage.

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“…These findings were in line with the findings of the current investigation, which showed that 17% EDTA and 17% EDTA-S were effective at removing smear layers. 14,15 Babgi et al conducted research on 15 healthy singlerooted teeth in 2020. Four equal groups of scaled roots were created; the first group had no chemical treatment, while the other three received either HA, 17% EDTA, or 0.2% CHX gel as conditioning agents.…”

Section: Discussionmentioning

confidence: 99%

“…These findings were in line with the findings of the current investigation, which showed that 17% EDTA and 17% EDTA-S were effective at removing smear layers. 14,15…”

Section: Discussionmentioning

confidence: 99%

Comparison of the Efficacy of 17% EDTA and 17% EDTA-S as Root Conditioning Agents: An in vitro Study

Anurag,

Pasupuleti,

Penmetsa

et al. 2023

Journal of Advanced Oral Research

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Objectives: The study’s objective is to assess the capacity of 17% EDTA (ethylene diamine tetraacetic acid) and 17% EDTA-S (sodium lauryl sulphate) on periodontally infected root surfaces as well as their capacity to remove the smear layer. Methods: Groups A (EDTA) and B (EDTA-S) were randomly selected from among 40 single-rooted teeth that had to be extracted due to the mobility. Sections of these teeth were subjected to a 3-minute “Active Burnishing Technique” treatment with 17% EDTA and 17% EDTA-S, followed by a 2-minute saline washing, and then investigated by using an electron microscope. The teeth’s root surface changes were evaluated using Sampaio’s Index, surface morphology, smear layer presence, dentinal tubule patency, and other factors. The results of this study were statistically examined using the paired “t” test. The significance threshold was established at P-value = .05. Results: The outcomes demonstrated that Group B benefited statistically from the elimination of the smear layer and the patency of the dentinal tubules ( P < .01). In the EDTA and EDTA-S groups, there were 85.508.75 and 91.706.20 patent dentinal tubules revealed, respectively. The total surface area exposed by EDTA was 163.88 ± 24.68 and EDTA-S was 182.91 ± 28.16 with a P-value <.01. Conclusion: According to the study’s findings, as compared to EDTA, EDTA-S is more successful at exposing dentinal tubules and removing the smear layer, making it a useful root conditioning agent.

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Comparison of the efficacy of ethylenediaminetetraacetic acid and tetracycline hydrochloride as root conditioning agents: An in vitro study

Cited by 4 publications

References 23 publications

Scanning electron microscopic analysis of 5% glycolic acid as a novel alternative to 17% ethylenediaminetetraacetic acid in root biomodification: An in vitro study

Scanning electron microscopic analysis of 5% glycolic acid as a novel alternative to 17% ethylenediaminetetraacetic acid in root biomodification: An in vitro study

Treatment of root coverage with platelet rich fibrin and coronally advanced flap: A case report

Comparison of the Efficacy of 17% EDTA and 17% EDTA-S as Root Conditioning Agents: An in vitro Study

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