Comparison of the endemic Azorean<i>Hypericum foliosum</i>with other<i>Hypericum</i>species: antioxidant activity and phenolic profile

Rainha, Nuno; Lima, Elisabete; Baptista, José

doi:10.1080/14786419.2010.512560

Cited by 27 publications

(23 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This was in line with the results on the Y TP and consisted clear evidence that differences in Y TP were reflected on the antioxidant properties of the extracts. This assumption is in accordance with previous examinations on various Hypericum species, where it was shown that extracts with higher polyphenolic load also exhibited stronger antioxidant effects [24,25]. Similar results were reported for several Hypericum taxa [26][27][28].…”

Section: Antioxidant Activitysupporting

confidence: 81%

Optimisation of organic solvent-free polyphenol extraction from Hypericum triquetrifolium Turra using Box–Behnken experimental design and kinetics

et al. 2015

View full text Add to dashboard Cite

Hypericum triquetrifolium Turra is a plant rich in biologically functional polyphenolic phytochemicals. The efficient recovery of polyphenols from this material has not been previously investigated in depth, in terms of establishing an environmentally benign and cost-effective process that would aim at producing extracts enriched in polyphenolic compounds. The objective of the present study was the examination of the efficiency of water/ glycerol mixtures in extracting polyphenols from dried aerial parts of H. triquetrifolium Turra and its critical comparison with water. Extraction temperature and time were optimised using response surface methodology, while comparative assessment of the extraction efficiency between water/glycerol and water was carried out using kinetics. The results showed that 10 % (w/v) aqueous glycerol at 70°C provided very satisfactory extraction yield in total polyphenols (54.83 mg gallic acid equivalents per g of dry weight), which was significantly higher than that attained with water (17.3 %). Similar results were drawn for the reducing power, in concurrence with the polyphenolic concentration. Liquid chromatography-mass spectrometry analysis showed that the polyphenolic profile of water/glycerol extract was composed by polar substances, such as chlorogenic acids and quercetin glycosides.Diffusion (m 2 s -1 ) dw Dry weight (g) h Initial extraction rate (mg g -1 min -1 ) k Extraction rate constant (g mg -1 min -1 ) P R Reducing power (lmol AAE g -1 dw) R Effective particle radius (m)

show abstract

Section: Antioxidant Activitysupporting

confidence: 81%

Optimisation of organic solvent-free polyphenol extraction from Hypericum triquetrifolium Turra using Box–Behnken experimental design and kinetics

et al. 2015

View full text Add to dashboard Cite

show abstract

“…In the present investigation, it was observed that maximum amount of Chlorophyll a and chlorophyll b and is found in leaf and minimum in root of Tinospora cordifolia. In consonance to this Rainha et al [13] also found best result in the anatomical part of Hypericum foliosum. In contrats to this Havsteen [14], found maximum chlorophyll result in callus of Triticum aestivum and other medicinally important plants.…”

Section: Discussionsupporting

confidence: 60%

Primary Metabolite Profiling of Tinospora cordifolia

Sharma¹,

Batra²

2016

Nat Prod Chem Res

View full text Add to dashboard Cite

Plants are the sources of many bioactive compounds containing many primary metabolites like, carbohydrates (starch, sugar), proteins, phenols, ascorbic acid etc. are useful for flavoring, fragrances, insecticides, sweeteners and natural dyes (Kaufman). During the present research work, root, stem, leaf and calli of the plant were evaluated quantitatively for the analysis of chlorophyll, sugars, starch, protein, ascorbic acid and phenols. Keeping in view the importance of these primary metabolites the present studies for biochemical evaluation of primary metabolites from different parts of Tinospora cordifolia was undertaken.

show abstract

“…The antioxidant effects of hydroalcoholic SJW extracts are not surprising since they contain up to 10% flavonoids which are well-known antioxidants. Polyphenol-rich Hypericum species all display pronounced antioxidant properties [41,42]. An SJW extract specifically enriched in flavonoids (quercetin and its derivatives) quenched DPPH with an IC 50 = 10.6 μg/mL and superoxide radical with an IC 50 = 54.3 μg/mL in a concentration-dependent manner.…”

Section: Antioxidative Activitymentioning

confidence: 99%

Topical Application of St. Johnʼs Wort (Hypericum perforatum)

Seelinger²,

2013

View full text Add to dashboard Cite

St. John's wort (Hypericum perforatum) has been intensively investigated for its antidepressive activity, but dermatological applications also have a long tradition. Topical St. John's wort preparations such as oils or tinctures are used for the treatment of minor wounds and burns, sunburns, abrasions, bruises, contusions, ulcers, myalgia, and many others. Pharmacological research supports the use in these fields. Of the constituents, naphthodianthrones (e.g., hypericin) and phloroglucinols (e.g., hyperforin) have interesting pharmacological profiles, including antioxidant, anti-inflammatory, anticancer, and antimicrobial activities. In addition, hyperforin stimulates growth and differentiation of keratinocytes, and hypericin is a photosensitizer which can be used for selective treatment of nonmelanoma skin cancer. However, clinical research in this field is still scarce. Recently, sporadic trials have been conducted in wound healing, atopic dermatitis, psoriasis, and herpes simplex infections, partly with purified single constituents and modern dermatological formulations. St. John's wort also has a potential for use in medical skin care. Composition and stability of pharmaceutical formulations vary greatly depending on origin of the plant material, production method, lipophilicity of solvents, and storage conditions, and this must be regarded with respect to practical as well as scientific purposes.

show abstract

Comparison of the endemic AzoreanHypericum foliosumwith otherHypericumspecies: antioxidant activity and phenolic profile

Cited by 27 publications

References 20 publications

Optimisation of organic solvent-free polyphenol extraction from Hypericum triquetrifolium Turra using Box–Behnken experimental design and kinetics

Optimisation of organic solvent-free polyphenol extraction from Hypericum triquetrifolium Turra using Box–Behnken experimental design and kinetics

Primary Metabolite Profiling of Tinospora cordifolia

Topical Application of St. Johnʼs Wort (Hypericum perforatum)

Contact Info

Product

Resources

About