Comparison of the Tei index with invasive measurements of right ventricular function

Grignola, Juan C.; Ginés, Fernando; D, Guzzo

doi:10.1016/j.ijcard.2005.10.012

Cited by 35 publications

(29 citation statements)

References 46 publications

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“…So far the echocardiographic parameters are concerned; MPI (Myocardial performance index) is well correlated with tricuspid regurgitation which is a manifestation of dilated right ventricle [7]. The index reflects RV impairment and the severity of impairment is proportional to the velocity of tricuspid regurgitation [8].…”

Section: Discussionmentioning

confidence: 99%

Assessment of RV Function in Patients of (COPD)

Das

Tapadar

Mahapatra

et al. 2014

JCDR

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Section: Discussionmentioning

confidence: 99%

Assessment of RV Function in Patients of (COPD)

Das

Tapadar

Mahapatra

et al. 2014

JCDR

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“…We used RV +/-dP/dt as reference values to evaluate RV systolic and diastolic functions. The RV peak +/-dP/dt are the most commonly used indices for assessing ventricular function [15,23,25,42]. However, these indices are influenced by ventricular preload and afterload.…”

Section: Discussionmentioning

confidence: 99%

“…However, these indices are influenced by ventricular preload and afterload. Therefore, other invasive indices of the ventricular function, such as maximal elastance (Emax), preload recruitable stroke work, chamber stiffness, and the time constant of relaxation (Tau), may reduce the impact from ventricular preload and afterload [15,25,42].…”

Section: Discussionmentioning

confidence: 99%

“…Moreover, the RV Tei index was not correlated with RV pressure overload; however, it was correlated with parameters of RV function obtained by right heart catheterization in patients with PH [33,37]. In addition, it was discussed that the increased afterload may not solely affect the RV Tei index, which is substantially related to the RV systolic and diastolic function [15]. The elevation of RV Tei index in TR dogs with PH may be caused by RV dysfunction that was mainly impaired by chronic PH in our study.…”

Section: Discussionmentioning

confidence: 99%

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Evaluation of Right Ventricular Tei Index (Index of Myocardial Performance) in Healthy Dogs and Dogs with Tricuspid Regurgitation

Teshima

Asano

Iwanaga

et al. 2006

The Journal of Veterinary Medical Science

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ABSTRACT. Right ventricular (RV) Tei index (index of myocardial performance) has been demonstrated to be clinically useful in estimating RV function in various human cardiac diseases. The purposes of this study were to validate the correlation between RV Tei index and RV function obtained by cardiac catheterization in healthy dogs, and to evaluate the RV Tei index in dogs with tricuspid regurgitation (TR). In healthy dogs, the RV Tei index significantly correlated with the RV peak +dP/dt (r=-0.80, p<0.0001) and -dP/dt (r=0.69, p=0.0001). In normal dogs, the RV Tei index was not significantly correlated with heart rate, body weight, and age. The RV Tei index significantly increased in dogs with moderate to severe TR (0.39 ± 0.35, p=0.0015), filariasis (0.46 ± 0.16, p=0.0131), and trivial to mild TR and severe mitral regurgitation (MR; 0.61 ± 0.14, p=0.0017) when compared with the normal dogs (0.17 ± 0.10). In addition, the RV Tei index in dogs with TR significantly increased in association with pulmonary hypertension [PH(-), 0.19 ± 0.09; PH(+), 0.65 ± 0.14; respectively p<0.0001]. Our study has demonstrated that RV Tei index is a feasible approach to estimate RV function in dogs and is not influenced by heart rate, body weight, and aging. Right ventricular (RV) function plays an important role in determining cardiac output and functional capacity in humans [1,28]. RV dysfunction has been observed in various cardiac disorders such as pulmonary hypertension (PH) [17,37], idiopathic dilated cardiomyopathy (DCM) [22], and heart failure [7,8,27].RV function can be evaluated by cardiac catheterization with RV peak +/-dP/dt, Tau and RV ejection fraction. However, this method is invasive, and it is difficult to evaluate the RV function due to the complex structural geometry, mechanical properties, and contraction pattern of the right ventricle [12,16].A decade ago, the Tei index (index of myocardial performance) derived from pulsed Doppler echocardiography was proposed in human medicine [36,39]. The Tei index is defined as the sum of isovolumetric contraction time (ICT) and isovolumetric relaxation time (IRT) divided by ejection time (ET), and it has been reported to reflect comprehensive cardiac function, including systolic and diastolic performances, in humans [36,39]. The Tei index is a simple and reproducible technique, and is relatively independent of heart rate [4,39] and age [19]. In addition, the Tei index has been demonstrated to be clinically useful in estimating the prognosis in human patients with primary PH [37,44], DCM [9], cardiac amyloidosis [38], and myocardial infarction [32]. It could be used for evaluating the RV function as well as the left ventricular function that is unrelated to the complex RV geometric structure [10, 11, 19, 24, 33-35, 37, 44].In small animal medicine, RV dysfunction is suspected in dogs with various cardiac diseases such as left-sided heart failure, pulmonary stenosis, tricuspid dysplasia, dirofilariasis, idiopathic cardiomyopathy, cor pulmonale, and idiopathic or secondary PH...

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“…As an example, the interest of the Tei index (TEI), a marker of global myocardial performance, has been demonstrated for the diagnosis and therapeutic follow-up of PAH in man and sheep. [13][14][15] However, to date, this variable has been studied only in healthy dogs. 16 Tissue Doppler imaging (TDI) is an ultrasound technique that allows quantitative assessment of segmental myocardial motion.…”

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confidence: 99%

Diagnostic Value of Echo-Doppler and Tissue Doppler Imaging in Dogs with Pulmonary Arterial Hypertension

Serres¹,

Chetboul²,

Gouni³

et al. 2007

J Vet Int Med

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Background: Diagnosis of pulmonary arterial hypertension (PAH) relies on Doppler measurement of pulmonic and tricuspid regurgitation (TR). However, these are not always detectable.Hypothesis: Tissue Doppler imaging (TDI), a novel noninvasive ultrasound technique, provides indirect but sensitive and specific assessment of elevated systolic pulmonary artery pressure (SPAP) in dogs.Animals: One hundred and five dogs with TR. Methods: Prospective observational study. Dogs were categorized as presenting normal (group 1, n 5 45), mildly increased (group 2, n 5 19), or moderately to severely increased (group 3, n 5 41) SPAP, based on TR peak velocities (,2.5, 2.5-3.0, and .3.0 m/s, respectively). Ten quantitative echo-Doppler-and TDI-derived variables were assessed, including the main pulmonary arterial diameter to aortic diameter ratio, pulmonary flow acceleration time, and acceleration-to-ejection time ratio, the Tei index of right ventricular function, and 6 longitudinal basal right ventricular TDI variables.Results: A significant correlation was observed between SPAP and each of the 10 tested variables (P , .05). Conventional echo-Doppler variables were less discriminating than the TDI for predicting increased SPAP. The combined systolic and diastolic right TDI index had the highest sensitivity and specificity (89% and 93% respectively, for a cutoff of 11.8 cm/s) and could discriminate between dogs in group 1 from dogs in group 2.Conclusions and Clinical Importance: TDI provided effective predictors of systolic PAH and demonstrated that both alterations in right-sided systolic and diastolic myocardial function can occur with mild increases in SPAP.

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Comparison of the Tei index with invasive measurements of right ventricular function

Cited by 35 publications

References 46 publications

Assessment of RV Function in Patients of (COPD)

Assessment of RV Function in Patients of (COPD)

Evaluation of Right Ventricular Tei Index (Index of Myocardial Performance) in Healthy Dogs and Dogs with Tricuspid Regurgitation

Diagnostic Value of Echo-Doppler and Tissue Doppler Imaging in Dogs with Pulmonary Arterial Hypertension

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