Comparison of therapeutic effects between selective amygdalohippocampectomy and anterior temporal lobectomy for the treatment of temporal lobe epilepsy: A meta-analysis

Zhang

et al. 2016

Seizure

Section: Discussionmentioning

confidence: 94%

Prognostic factors for seizure outcome in patients with MRI-negative temporal lobe epilepsy: A meta-analysis and systematic review

Zhang

et al. 2016

Seizure

J Neurol Neurosurg Psychiatry

“…The choice of resective surgery for TLE remains elusive. Previous meta-analyses have shown discordant findings, with ATL reported to achieve better seizure outcome when compared with SAH in two meta-analyses,4 5 and similar seizure outcome was reported with ATL and SAH in another meta-analysis 6. Hu et al 4 also showed that there was no significant difference in full-scale performance and verbal IQ scores of ATL relative to SAH.…”

Section: Introductionmentioning

confidence: 90%

Systematic review and network meta-analysis of resective surgery for mesial temporal lobe epilepsy

Jain

Tomlinson

Snead

et al. 2018

Stereotact Funct Neurosurg

“…Along these lines of reasoning, limited ablations should be preferred over more generous approaches [36]. However, some authors have found improved seizure control and worse neuropsychological outcome after larger resections [37], while others did not find any statistically significant difference between larger and more restricted procedures concerning seizure and neuropsychological outcome [38]. …”

Section: Discussionmentioning

confidence: 99%

Five-Year Neuropsychological Outcome after Stereotactic Radiofrequency Amygdalohippocampectomy for Mesial Temporal Lobe Epilepsy: Longitudinal Study

Krámská¹,

Vojtěch²,

Lukavský³

et al. 2017

Purpose: To assess the neuropsychological performance recoded over a period of 5 years after stereotactic radiofrequency amygdalohippocampectomy (SAHE) in the treatment of mesial temporal lobe epilepsy. Material and Methods: Thirty patients (mean age 38 years, 14 females/16 males) were included in this study. Twenty-one patients were treated on the left side, 9 on the right. Patients underwent neuropsychological evaluation by the Wechsler Adult Intelligence Scale-Revised and the Wechsler Memory Scale-Revised preoperatively and 5 years after SAHE. Results: Twenty-three (77%) patients were classified as Engel class I. At the group level, we found significant increases in all intelligence domains (Global, Visual, and Performance) by 19.1 (7.4), 15.8 (6.1), and 19.1 (7.9) points, respectively. Significant improvements were also detected in all memory measures (Global, Verbal, Visual, Attention/Concentration, Delayed Recall) by 19.4 (14.2), 16.9 (13.3), 19.0 (14.7), 15.3 (15.0), and 24.6 (13.4), respectively. Patients with left-sided surgery improved significantly more in Attention/Concentration. Otherwise, there were no statistically significant differences in memory function improvements between subgroups according to the operated side. Conclusion: After SAHE, we found favorable long-term neuropsychological outcomes. These results could be caused by incomplete destruction of target structures and minimization of collateral damage that possibly enables adaptive postoperative neuronal reorganization.