Comparison of therapeutic effects of anterior decompressionand posterior decompression on thoracolumbar spine fracture complicated with spinal nerve injury

Cui, Hongxun; Guo, Jiayi; Yang, Lei; Yanxing, Guo; Guo, Malong

doi:10.12669/pjms.312.6474

Cited by 7 publications

(6 citation statements)

References 15 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The median number of individuals with SCI was 15 (range: 4‐558, interquartile range: 10‐32), the median total sample size was 18 (range: 4‐582, interquartile range: 10‐34), see Figure . The subset of studies with a total sample size >100 (n = 12) comprised multicenter as well as single‐center trials . We found that 167 out of 207 (81%) eligible studies met our definition of a small‐sample size study.…”

Section: Resultsmentioning

confidence: 97%

See 1 more Smart Citation

Sample sizes and statistical methods in interventional studies on individuals with spinal cord injury: A systematic review

Zimmermann

Bolter

Sluka

et al. 2019

J Evidence Based Medicine

View full text Add to dashboard Cite

Aim Prevalence and incidence of spinal cord injury (SCI) are low. However, sample sizes have not been systematically examined yet, although this might represent useful information for study planning and power considerations. Therefore, our objective was to determine the median sample size in clinical trials on SCI individuals. Moreover, within small‐sample size studies, statistical methods and awareness of potential problems regarding small samples were examined. Methods We systematically reviewed all studies on human SCI individuals published between 2014 and 2015, where the effect of an intervention on one or more health‐related outcomes was assessed by means of a hypothesis test. If at least one group had a size <20, the study was classified as a small sample size study. PubMed was searched for eligible studies; subsequently, data on sample sizes and statistical methods were extracted and summarized descriptively. Results Out of 8897 studies 207 were included. Median total sample size was 18 (range 4‐582). Small sample sizes were found in 167/207 (81%) studies, resulting limitations and implications for statistical analyses were mentioned in 109/167 (65%) studies. Conclusions Although most recent SCI trials have been conducted with small samples, the consequences on statistical analysis methods and the validity of the results are rarely acknowledged.

show abstract

Section: Resultsmentioning

confidence: 97%

“…The subset of studies with a total sample size >100 (n = 12) comprised multicenter [26][27][28] as well as single-center trials. [29][30][31][32][33][34][35] We found that 167 out of 207 (81%) eligible studies met our definition of a small-sample size study.…”

Section: Sample Sizesmentioning

confidence: 99%

Sample sizes and statistical methods in interventional studies on individuals with spinal cord injury: A systematic review

Zimmermann

Bolter

Sluka

et al. 2019

J Evidence Based Medicine

View full text Add to dashboard Cite

show abstract

“…No damage to PLC type A3 thoracolumbar fractures patients, in order to avoid because of the need of the spinal canal decompression and man-made destruction of PLC, group adopts comprehensive skills in orthopaedic surgery after CT scan quickly, understand the vertebral height restoration after spinal canal fracture block reset, and then make a decision according to the fracture block restoration situation accurate treatment plan, as much as possible to maintain the stability of spine rear, retained the rear ligament complex. Group found that 60.8% of the patients with hyperextension position after reset and nail stick open orthopaedic spinal canal fracture block has been reset, there is no need for any spinal canal decompression, only 39.8% of patients need decompression, analysis the indirect reduction and the cause of the failure injury time is too long after adhesion, fracture hematoma brosis after the ip, fracture blocks from longitudinal ligaments and other reasons, led to into vertebral canal fracture piece of reduction and incomplete or inadequate [16][17][18][19][20][21]. According to the CT information of intraoperative three-dimensional reconstruction, the position and size of the fracture lumps in the inboards were located precisely.…”

Section: Discussionmentioning

confidence: 99%

Treatment of fresh thoracolumbar vertebral burst fracture based on intraoperative CT scan

y¹,

Zhou

et al. 2020

Preprint

View full text Add to dashboard Cite

ObjectiveTo evaluate the value of intraoperative CT scanning in the treatment of fresh thoracolumbar burst fractures .MethodThe data of patients with thoracolumbar fractures from January 2008 to January 2015 were analyzed retrospectively,79 cases were treatment group which were treated with intraoperative CT scan and decompression mode was determined according to CT scan results during the period from October 2012 to January 2015; 82 patients as the observation group were treated without intraoperative CT scan and direct laminectomy were performed during the period from January 2008 to October 2012. In the treatment group, it is no further decompression of the spinal canal when the CT showed a reduction of the fracture block into the spinal canal, If the intraoperative CT showed that the fractures still occupied the spinal dura mater according to the three-dimensional CT information, The position and the size of the fracture of the spinal canal were determined, and the unilateral laminectomy was performed corresponding to the position of the lamina and intervertebral ligamentum flavum. The operative time, bleeding volume, neurological function, height of the anterior vertebral compression and Cobb angle were compared between the two groups.ResultIn the treatment group, CT scan showed 48 cases (60.8%) entered the spinal canal fracture completely or basically reset .31 cases (39.2%) still occupied the spinal canal compression spinal dura mater. There were significant differences in the operation time and bleeding volume between the two groups. The treatment group was less than the control group. There was no infection, secondary spinal cord injury, loose fixation and other complications. There was no difference in the ASIA classification before and after operation. The anterior vertebral height and COBB angle of the two groups were significantly improved compared with those before operation. There was no significant difference between the two groups in the postoperative height and COBB angle, but after 2 years the difference was statistically significant between the two groups, to retain the rear ligament complex treatment group was significantly better than the control group.ConclusionPatients of thoracolumbar vertebral fracture in hyperextension position combined with internal fixation can achieve good correction effect. Orthopedic postoperative CT scan and according to the results of the scan precision treatment can simplify the operation, there was no difference in clinical efficacy compared with total laminectomy, but some patients avoid the spinal canal decompression and part were treated by small fenestration laminectomy decompression, which is conducive to the protection of spinouts ligament complex integrity.

show abstract

“…Anterior decompression with internal fixation was considered the study group [8], while posterior decompression with internal fixation was considered the control group [9]. Preoperative routine examinations were completed in both groups.…”

Section: Methodsmentioning

confidence: 99%

A Comparative Study on Functional Recovery, Complications, and Changes in Inflammatory Factors in Patients with Thoracolumbar Spinal Fracture Complicated with Nerve Injury Treated by Anterior and Posterior Decompression

Jiang¹,

Wang

Yu³

et al. 2019

Med Sci Monit

View full text Add to dashboard Cite

BackgroundThe aim of this study was to evaluate 2 methods to treat patients with thoracic lumbar spine fracture with merging spinal cord injury, including complications of surgery and the influence of inflammatory factors.Material/MethodsEighty patients were randomly divided into an anterior decompression group (study group) or a posterior decompression group (control group) to observe perioperative complications, evaluate preoperative and postoperative nerve function, and evaluate the 6-month injured vertebral height and Cobb angle of the vertebral bodies. The expression level of TGF-β2 on day 1, day 7, day 15, and day 30 after treatment was detected by enzyme-linked immunosorbent assay (ELISA).ResultsThe nerve function sensation score, the height of the vertebral body, and the recovery of Cobb angle were better for the anterior decompression group than the posterior decompression group and the effect was significant (P<0.05). The complication rate for the posterior decompression group was lower than the anterior decompression group. The level of TGF-β2 in the anterior decompression group was higher than in the posterior decompression group for the same times: after day 1, day 7, day 15, and day 30 after treatment (P<0.05).ConclusionsPatients who had thoracic lumbar spine fracture with merging spinal cord injury and who had anterior fixation achieved a good fixation effect; their neurologic and vertebral injury recovery was better. However, this relatively complex and traumatic surgery must consider the clinical manifestations and fractures of the patients and select the appropriate surgical approach.

show abstract

Comparison of therapeutic effects of anterior decompressionand posterior decompression on thoracolumbar spine fracture complicated with spinal nerve injury

Cited by 7 publications

References 15 publications

Sample sizes and statistical methods in interventional studies on individuals with spinal cord injury: A systematic review

Sample sizes and statistical methods in interventional studies on individuals with spinal cord injury: A systematic review

Treatment of fresh thoracolumbar vertebral burst fracture based on intraoperative CT scan

A Comparative Study on Functional Recovery, Complications, and Changes in Inflammatory Factors in Patients with Thoracolumbar Spinal Fracture Complicated with Nerve Injury Treated by Anterior and Posterior Decompression

Contact Info

Product

Resources

About