2.05% were in "no response" group, 1.46% in "Low response" group and 96.49% in "Good response" group. Conclusion: Immunological response in the smoking staff was significantly less (p < 0.001) but no significant difference was observed in the response between genders (p = 0.127) and no case of hyperlipidemia was reported. There was a significant reverse linear relation between age and antibody titer in the studied staff (p = 0.003, R = 0.162) but no significant linear relation was observed between weight, height and BMI and antibody titer.