Comparison of Topical Therapy for Striae Alba (20% Glycolic Acid/0.05% Tretinoin Versus 20% Glycolic Acid/ 10% L-Ascorbic Acid)

Ash, Keith; Lord, Jeff; Zukowski, Mark L.

doi:10.1111/j.1524-4725.1998.tb04262.x

Cited by 68 publications

(48 citation statements)

References 26 publications

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“…Once SG have developed, attempts at treating them with a variety of lasers and topical tretinoin, alpha hydroxyl acids and vitamin C have shown mild improvement at best. [11][12][13] Despite restricting our trial to nulliparas in an attempt to limit it to the development of de novo SG, a high percentage of women (45.1 and 48.8% in cases and controls, respectively) had stretch marks at the enrolment. However, old SG were easy to differentiate from new ones at the postpartum assessment due to a clear difference in colour and texture.…”

Section: Discussionmentioning

confidence: 99%

Cocoa butter lotion for prevention of striae gravidarum: a double‐blind, randomised and placebo‐controlled trial*

Osman

Usta

Rubeiz

et al. 2008

BJOG

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Objective To assess whether application of cocoa butter lotion reduces the development of striae gravidarum (SG).Design Multicentre, double-blind, randomised and placebocontrolled trial.Setting Beirut and Tripoli, Lebanon.Population Nulliparous women presenting for prenatal care.Methods Nulliparous women presenting in the first trimester were randomly assigned to receive a lotion containing cocoa butter or a placebo lotion. Women were instructed to apply the assigned lotion daily until delivery.Main outcome measure The development of striae over the abdomen, breasts and thighs postpartum.Results Of 210 women enrolled, 175 (83%) completed the study. Ninety-one women received the study lotion and 84 received the placebo. There was no difference in the development of SG (45.1% versus 48.8%; P = 0.730) or the severity of SG between cases and controls. The results did not change when presence of stretch marks at enrolment or compliance with the regimen were taken into account.Conclusion Topical application of a lotion containing cocoa butter does not appear to reduce the likelihood of developing striae gravidarum.

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Section: Discussionmentioning

confidence: 99%

Cocoa butter lotion for prevention of striae gravidarum: a double‐blind, randomised and placebo‐controlled trial*

Osman

Usta

Rubeiz

et al. 2008

BJOG

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“…Studien über die lokale Anwendung von 20%iger Glykolsäure in Kombination mit 0,05%igem Tretinoin bzw. 10%iger L-Ascorbinsäure zeigten respektable und auch histologisch objektivierbare Verbesserungen der Striae [4,12]. Über die alleinige Anwendung einer Tretinoincreme werden unterschiedliche Erfolge berichtet.…”

Section: Fazit Für Die Praxisunclassified

Was hilft am besten bei Bindegewebsschwäche?

2009

J. f. Ästhet. Chirurgie

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Sie sind ein typisch weibliches Problem. Denn obwohl Cellulite und Striae distensae auch bei Männern auftreten können, sind doch hauptsäch-lich Frauen davon betroffen. Häu-fig werden sie als unästhetisch und somit störend empfunden. Cremes, Massagen und Hormone sollen helfen, die Haut wieder glatt zu bekommen. Doch welche Art Behandlung hilft wirklich bei Orangenhaut und Schwangerschaftsstreifen? Cellulite Cellulite, auch bekannt als Orangenhaut oder Dermopanniculosis deformans, bezeichnet das Nebeneinander von Vorwöl-bungen und Dellen an der Hautoberfläche, insbesondere an Oberschenkeln, Hüfte und Gesäß. Die Cellulite beschreibt einen Hautzustand und keine Erkrankung. Der früher gebrauchte Begriff »Cellulitis« weist auf die ursprüngliche Annahme hin, dass ein ursächlicher Zusammenhang mit entzündlichen Veränderungen im Fett-und Bindegewebe oder Weichteilrheuma besteht. Heute ist die Bezeichnung »Cellulitis« für entzündliche Erkrankungen der Subkutis reserviert [30]. Die Cellulite ist nicht etwa ein Phäno-men der Neuzeit; lediglich ihr ästhetischer Anspruch hat sich geändert. Während die großen Meister des Mittelalters die ausladenden Fettpolster der Oberschenkel ihrer weiblichen Modelle durch leuchtende Farbakzente noch betonten, ist die Cellulite heute ein ästhetisch störendes Problem.

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“…A variety of treatment modalities have been used for the treatment of striae distensae, such as tretinoin cream [6], a combination of tretinoin and glycolic acid or ascorbic acid and glycolic acid [7], which have shown some effect in the early stages. Microdermabrasion can be a useful therapeutic option with a possible stimulatory effect on type I procollagen formation [8].…”

Section: Introductionmentioning

confidence: 99%

Microneedling system alone versus microneedling system with trichloroacetic acid in the management of abdominal striae rubra

Sanad¹,

Aginaa²,

Sorour³

2015

Journal of the Egyptian Womenʼs Dermatologic Society

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BackgroundStriae distensae or stretch marks, although not a health risk, are of significant cosmetic concern as it affects the patient's psychological condition. Although many treatment modalities have been attempted with variable results, there is no standard treatment modality for it. Objective To compare the efficacy of a microneedling system (dermaroller) when used alone or combined with 15-30% trichloroacetic acid (TCA) in the management of striae rubra. Patients and methodsThis clinical trial included 30 female patients with abdominal striae rubra treated with a dermaroller alone on the left side of the abdomen (GI) and with a dermaroller + 15-30% TCA on the right side of the abdomen (GII). Patients were treated for six sessions at 3-week intervals. We assessed the clinical features (length, width, color, and texture) of striae in each group at every session and 3 weeks after the end of the sessions (follow-up). The response to treatment was assessed objectively by the treating physicians and skin biopsies stained with hematoxylin and eosin and picrosirius red stains. Subjective assessment of the clinical photographs and patient satisfaction scores was carried out by two uninvolved blind dermatologists at every session. Results A comparison between GI and GII at the follow-up session revealed statistically significant differences in length (P = 0.002), width (Po0.001), color, and texture (P = 0.049 and 0.041, respectively). More improvement in the striae was noted in GII, as 19 (63.3%) patients showed good to excellent improvement compared with 10 (33.3%) patients in GI. Skin biopsies in GII showed increased epidermal thickness after treatment (Po0.005). Collagen content was increased after treatment in both groups. Side effects including transient erythema, edema, burning pain, and hyperpigmentation were observed more in GII with increasing concentration of TCA peeling. ConclusionBoth dermaroller and dermaroller + 15-30% TCA are effective treatment modalities for striae rubra. However, dermaroller + 15-30% TCA gives better results and dermaroller alone has fewer side effects.

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Comparison of Topical Therapy for Striae Alba (20% Glycolic Acid/0.05% Tretinoin Versus 20% Glycolic Acid/ 10% L-Ascorbic Acid)

Cited by 68 publications

References 26 publications

Cocoa butter lotion for prevention of striae gravidarum: a double‐blind, randomised and placebo‐controlled trial*

Cocoa butter lotion for prevention of striae gravidarum: a double‐blind, randomised and placebo‐controlled trial*

Was hilft am besten bei Bindegewebsschwäche?

Microneedling system alone versus microneedling system with trichloroacetic acid in the management of abdominal striae rubra

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