Comparison of Total Antioxidant Capacity of Saliva in Women with Gestational diabetes mellitus and Non-diabetic Pregnant Women

Zamani-Ahari, Ulduz; Zamani-Ahari, Sahar; Fardiazar, Zahra; Falsafi, Parisa; Ghanizadeh, Milad

doi:10.4317/jced.53845

Cited by 13 publications

(18 citation statements)

References 29 publications

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“…HO-1 is thought to be an oxidative stress marker (6,7). On the other hand, the combined activity of all antioxidants is measured via the total antioxidant capacity (TAC), instead of measuring the activity of each agent separately, for example superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GSH-Px) (8).…”

Section: Introductionmentioning

confidence: 99%

Comparison of redox parameters in ovarian endometrioma and its malignant transformation

et al. 2018

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The present study aimed to evaluate the levels of oxidative stress and antioxidant markers in benign endometrioma (OE) and its malignant transformation [endometriosis-associated ovarian cancer (EAOC)] by measuring 8-hydroxy-2-deoxyguanosine (8-OHdG), heme oxygenase-1 (HO-1) and total antioxidant capacity (TAC/Heme-iron) alterations associated with disease progression. Cyst fluid samples from 44 patients with OE and 14 patients with EAOC were studied using an enzyme-linked immunosorbent assay. A χ test, t-test and Pearson correlation test were performed using SPSS version 22.0. The cut-off point, sensitivity and specificity of each marker for EAOC diagnosis were evaluated by receiver operating characteristic curve analysis. Cyst fluid 8-OHdG and HO-1 levels in the EAOC group were significantly decreased compared with the OE subjects (P=0.013 and P<0.001, respectively). The levels of TAC/Heme-iron in patients with EAOC were significantly higher compared with those in the OE subjects (P<0.001). The present study demonstrated a positive correlation between 8-OHdG and HO-1 levels (P=0.012). HO-1 exhibited the highest discriminant value for EAOC (Area Under the Curve=0.901). The optimal cut-off point of HO-1 for the diagnosis of EAOC was 2.314 ng/ml, with a sensitivity and specifity of 95.2 and 85.7%, respectively. The present study revealed a clear separation between the overall redox state in OE and EAOC. It was concluded that characteristic alterations in important factors in redox may be helpful for understanding the pathogenesis of the malignant transformation of endometriosis.

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Section: Introductionmentioning

confidence: 99%

Comparison of redox parameters in ovarian endometrioma and its malignant transformation

et al. 2018

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“…[7], ZAMANI-AHARI & al. [8]). Because of the cumulative effect of antioxidants, it is better to measure the combined activity of all the antioxidants or the total antioxidant capacity (TAC) instead of measuring the activity of each agent separated (ZAMANI-AHARI & al.…”

Section: Total Antioxidant Activity (Tac)mentioning

confidence: 99%

“…They inhibit the formation of free radicals, prevent or inhibit the activity of free radicals after they are formed, repair damages inflicted by the activity of free radicals and increase the excretion or absorption of damaged molecules (ZAMANI-AHARI & al. [8]). Antioxidant molecules are present in all body fluids and tissues (PUNJ & al.…”

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confidence: 99%

Studies regarding salivary total antioxidant activity in different types of orthodontic treatement

RĀDUCANU¹,

Mihai²,

CARAIANE³

et al. 2019

Rom Biotechnol Lett.

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The defensive mechanism of the human body includes a wide range of antioxidants (non-enzymatic and enzymatic) that can eliminate reactive oxygen species and prevent their harmful consequences on the host. Total antioxidant capacity (TAC) is a biomarker used to measure the antioxidant potential of body fluids and it may be the most relevant parameter for assessing the defense capabilities. Because of the cumulative effect of antioxidants, it is better to measure the combined activity of all the antioxidants (total antioxidant capacity) instead of measuring the activity of each agent separated. The aim of this study is to investigate the effect of different orthodontic appliances (fixed and removable-aligners) on salivary total antioxidant capacity and if is a correlation between TAC and oral injuries made by them. Three groups of subjects have been tested: one group of ten patients with metallic fixed appliances, one group of ten patients with aligners, and a control group consisting in ten subjects. 2,2-diphenyl-1-picrylhydrazyl (DPPH) method was used for TAC assessment and salivary samples were obtained from all individuals before treatment, at two weeks from the beginning, at one and two month of treatment. Also, it was quantified the presence of the injuries in the mucosa (clinical parameter). The result shows that different types of orthodontic appliances increase differently the TAC and seems to be influenced by the injuries. KeywordsTotal antioxidant capacity (TAC), DPPH method, orthodontic aligners, fixed appliances.To cite this article: MĀDĀLINA RA, SEBASTIAN M, AURELIANA C, VICTORIA B.Studies regarding salivary total antioxidant activity in different types of orthodontic treatement.

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“…20 Wanita hamil yang mengalami DM juga dilaporkan memiliki KAT yang lebih rendah dibandingkan wanita hamil normal. 21 Keadaan KAT dipengaruhi oleh dua faktor yaitu faktor internal dan faktor eksternal. Faktor internal adalah produksi atau pembentukan radikal bebas, dan faktor eksternal yaitu asupan zat gizi dan senyawa non-gizi sebagai antioksidan sekunder.…”

Section: Pembahasanunclassified

Pengaruh Kebiasaan Konsumsi Sayur, Buah dan Perokok Pasif terhadap Kapasitas Antioksidan Total Ibu Hamil

Nadimin

2018

MKMI

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Ketersediaan antioksidan selama kehamilan mengalami penurunan seiring dengan peningkatan umur kehamilan dan dipengaruhi oleh faktor lingkungan, seperti paparan asap rokok dan kebiasaan konsumsi sayur dan buah. Penelitian dilaksanakan secara cross sectional study dengan menggunakan sampel ibu hamil (umur kehamilan 20-26 bulan) non-anemia sebanyak 70 orang yang dipilih secara purposive sampling. Pengumpulan data Kapasitas Antioksidan Total (KAT) menggunakan metode Elisa (Enzyme-liked immunosorbent assay), kebiasaan konsumsi sayur dan buah dikumpul dengan Food Frequency Questionaire (FFQ) dan kebiasaan merokok menggunakan wawancara. Hasil penelitian menunjukkan 37,1% ibu hamil tergolong perokok pasif dan jarang mengonsumsi sayuran dan buah-buah (>60%). Rerata KAT ibu hamil mencapai 2,73+1,48 mmol/l.KAT ibu hamil perokok pasif lebih rendah secara signifikan dibandingkan ibu hamil non-perokok pasif (p=0,038). Umumnya ibu hamil yang “sering” konsumsi sayuran dan buah memiliki KAT yang lebih tinggi. Namun, KAT yang lebih tinggi secara signifikan ditemukan pada ibu hamil yang sering mengonsumsi sawi hijau (p=0,049), daun kacang hijau (p=0,002), apel (p=0,007) dan pepaya (p=0,029). Paparan asap rokok dan kurang mengonsumsi sayura dan buah menurunkan KAT pada ibu hamil. Sebaiknya ibu hamil meningkatkan konsumsi sayuran dan buah dan menghindari paparan asap rokok.

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Comparison of Total Antioxidant Capacity of Saliva in Women with Gestational diabetes mellitus and Non-diabetic Pregnant Women

Cited by 13 publications

References 29 publications

Comparison of redox parameters in ovarian endometrioma and its malignant transformation

Comparison of redox parameters in ovarian endometrioma and its malignant transformation

Studies regarding salivary total antioxidant activity in different types of orthodontic treatement

Pengaruh Kebiasaan Konsumsi Sayur, Buah dan Perokok Pasif terhadap Kapasitas Antioksidan Total Ibu Hamil

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