Comparison of two different laser photobiomodulation protocols on the viability of random skin flap in rats

Effect of photobiomodulation associated with cell therapy in the process of cutaneous regeneration in third degree burns in rats

“…It was identified that the groups treated with PBM alone or associated to hASCs obtained better results, proving the efficacy of the proposed treatments. Recent studies have pointed out that PBM is an effective technique in the maturation of type III collagen in type I, in addition to contributing effectively to its organization (Martignago et al, 2018; A.N. Otterço et al, 2018).…”

“…Within this context, photobiomodulation therapy (PBM) has been gaining prominence in recent decades, characterized by being a form of phototherapy that involves the application of low power monochromatic and coherent light in several types of wounds, being successful when used to induce healing, repair of complex wounds, and increased local vascularization (Brassolatti, de Andrade, Bossini, Otterço, & Parizotto, 2018; Hawkins & Abrahamse, 2006; Martignago et al, 2018; Otterço, Andrade, et al, 2018).…”

“…The literature shows that the use of PBM in the treatment of burns, especially in the early stages of the process promotes better healing and a shorter tissue repair time through the antioxidant effects provided by the therapy, such as the ability to modulate the intensity of the inflammatory infiltrate and to stimulate the production of macrophages and synthesis of collagen (Avci et al, 2013; Brassolatti et al, 2016). In addition, recent studies have demonstrated that PBM also stimulates subsequent steps in the repair process, assisting in the formation of granulation tissue through stimulation in fibroblast synthesis and formation of new vessels and maturation of type III collagen in type I (Fiório & Albertini, 2014; Martignago et al, 2018; Otterço, Andrade, et al, 2018).…”

A Fotobiomodulação No Processo Cicatricial Da Pele - Revisão Da Literatura / Photobiomodulation in Wound Healing Process - Literature Review

“…Os efeitos da fotobiomodulação se dão pela absorção da luz pelo fotorreceptor citocromo C oxidase, uma enzima da cadeia mitocondrial que quando excitada, ativa uma cascata de sinalização celular e acelera a transferência de elétrons; posteriormente, ocorre aumento eletroquímico na atividade mitocondrial, conferindo ainda aumento na síntese de ATP que levarão no processo cicatricial da pele à analgesia, ação anti-inflamatória, proliferação celular, neovascularização e regeneração tecidual [36][37][38][39][40][41][42][43][44][45][46][47][48][49][50][51] .…”

Applications of photobiomodulation in hearing research: from bench to clinic

“…Photobiomodulation (PBM) and low-level laser therapy (LLLT) use light to reduce pain [8][9][10] and inflammation [11][12][13][14][15], induce analgesia [16], and promote nerve and tissue repair [17][18][19][20][21]. As the laser power is low, tissue temperature does not rise [22].…”