Comparison of two different thermal techniques for the treatment of hepatocellular carcinoma

Percutaneous thermal ablation for primary hepatocellular carcinoma: A systematic review and meta‐analysis

“…15,16,29,31 No significant heterogeneity was found among studies reporting the 1-year overall survival (I 2 = 32%, P = 0.2). The randomeffects model pooled OR (95% CI) was 1.18 (0.46-3.03), P = 0.73 (Fig.…”

“…[14][15][16][17]30,31,34 There was no significant inter-study heterogeneity (I 2 = 0%, P = 0.71). The pooled OR (95% CI) using a random-effects model was 0.69 (0.44-1.08), P = 0.010 indicating a favorable trend towards RFA (Fig.…”

“…In five studies (705 subjects) that evaluated tumors confined to the Milan criteria (single tumor ≤5 cm or up to three tumors with each measuring ≤3 cm), 14,16,17,31,34 the pooled OR (95% CI) was 0.73 (0.45-1.19), P = 0.21. A further three studies (450 subjects) that looked at the use of RFA and MWA in treating HCC beyond the Milan criteria (single tumor >5 cm or >3 nodules), 29,32,33 the pooled OR (95% CI) was 1.88 (1.10-3.23), P = 0.02 indicating a benefit for MWA (Fig.…”

“…The pooled OR (95% CI) for the five high-quality studies 14,16,17,29,30 was 1.15 (0.69-1.92), P = 0.60 and for the five low-quality studies 15,[31][32][33][34] was 0.92 (0.49-1.73), P = 0.79 (Supporting Information Fig. S3).…”

A Recent Advance in Image-Guided Locoregional Therapy for Hepatocellular Carcinoma

“…The authors considered a high probability of long-term survival of patients with a single lesion ≤4.0 cm in maximum diameter and Child-Pugh class A cirrhosis. Numerous studies have compared MWA with RFA for treating HCC and found similar disease-free survival, cumulative survival, and complication rates in the two groups [68,69,70,71,72,73,74]. However, so far, only one RCT [68] has compared the efficacy of MWA with that of RFA, in a series of 72 patients (36 RFA/36 MWA) with equivalent background demographics and mean tumor sizes.…”