Comparison of Two Malnutrition Assessment Scales in Predicting Postoperative Complications in Elderly Patients Undergoing Noncardiac Surgery

Zhang, Fang; He, Shu-Ting; Zhang, Yan; Mu, Dong-Liang; Wang, Dong‐Xin

doi:10.3389/fpubh.2021.694368

Cited by 8 publications

(6 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The NRS2002 scale is commonly used to assess patients' nutritional status comprehensively. Previous results have shown that the NRS2002 score is associated with postoperative complications in patients [ 37 , 38 ]. Patients with poor preoperative nutritional status are at increased risk of postoperative anastomotic leakage, which may be due to the prolonged healing time of the anastomosis.…”

Section: Discussionmentioning

confidence: 99%

A preoperative prediction model based on Lymphocyte-C-reactive protein ratio predicts postoperative anastomotic leakage in patients with colorectal carcinoma: a retrospective study

Zhong

Lin

et al. 2022

BMC Surg

View full text Add to dashboard Cite

Background & Aims Lymphocyte-C-reactive Protein Ratio (LCR) has been demonstrated as a promising new marker for predicting surgical and oncological outcomes in colorectal carcinoma (CRC). However, anastomotic leakage (AL) is also likely related to this inflammatory marker. Herein, we aimed to identify preoperative predictors of AL and build and develop a novel model able to identify patients at risk of developing AL. Methods We collected 858 patients with CRC undergoing elective radical operation between 2007 and 2018 at a single center were retrospectively reviewed. We performed univariable and multivariable analyses and built a multivariable model that predicts AL based on preoperative factors. Propensity adjustment was used to correct the bias introduced by non-random matching of the LCR. The model's performance was evaluated by using the area under the receiver operator characteristic curves (AUROCs), decision curve analysis (DCA), Brier scores, D statistics, and R2 values. Results Age, nutrition risk screening 2002 (NRS2002) score, tumor location and LCR, together with hemoglobin < 90 g/l, were independent predictors of AL. The models built on these variables showed good performance (internal validation: c-statistic = 0.851 (95%CI 0.803–0.965), Brier score = 0.049; temporal validation: c-statistic = 0.777 (95%CI 0.823–0.979), Brier score = 0.096). A regression equation to predict the AL was also established by multiple linear regression analysis: [Age(≥ 60 year) × 1.281] + [NRS2002(≥ 3) × 1.341] + [Tumor location(pt.) × 1.348]-[LCR(≤ 6000) × 1.593]-[Hemoglobin(< 90 g/L) × 1.589]-6.12. Conclusion Preoperative LCR is an independent predictive factor for AL. A novel model combining LCR values, age, tumor location, and NRS2002 provided an excellent preoperative prediction of AL in patients with CRC. The nomogram can help clinical decision-making and support future research.

show abstract

Section: Discussionmentioning

confidence: 99%

A preoperative prediction model based on Lymphocyte-C-reactive protein ratio predicts postoperative anastomotic leakage in patients with colorectal carcinoma: a retrospective study

Zhong

Lin

et al. 2022

BMC Surg

View full text Add to dashboard Cite

show abstract

“…The results of a systematic review with the same tool showed that malnutrition patients are more at risk for mortality than the patients with normal nutrition and have a lower quality of life (35). Patients with more malnutrition than patients with normal nutrition are at risk for complications and manifestations after surgery, such as wound infection and recurrent pain (36). Also, the results of other studies show that there is a significant relationship between energy intake in patients hospitalized in ICUs and infection (37)(38)(39).…”

Section: Discussionmentioning

confidence: 99%

Relationship between Mini Nutritional Assessment Score and Infection in Critical Care Patients

Moghaddam

Lahiji

Panah

et al. 2022

Med. J. Islam. Republ. Iran

View full text Add to dashboard Cite

show abstract

“…The sample size estimation was based on the post‐operative morbidity and on the principle of 10 outcome events per variable. Referring to previous literatures, the morbidity in elderly patients was about 38% 24 . Using an estimated morbidity of 38% and for 20 predictors, we aimed to enrol 526 patients.…”

Section: Methodsmentioning

confidence: 99%

Effects of sarcopenia and frailty on postoperative recovery in elderly patients: A prospective cohort study

Guo,

Wang,

et al. 2023

J cachexia sarcopenia muscle

View full text Add to dashboard Cite

BackgroundSarcopenia and frailty are both age‐related declines in functional reserve that are linked to adverse health outcomes. It is critical to know about the outcomes of a combination of these conditions. The study aimed to investigate the effects of sarcopenia and frailty on postoperative recovery in elderly patients and to explore risk factors.MethodsThis prospective cohort study was conducted among 608 patients aged ≥60 years, American Society of Anesthesiologists I‐III, who were scheduled to undergo thoracic (non‐cardiac) and abdominal surgery from 1 March 2022 to 31 October 2022 at the Affiliated Hospital of Xuzhou Medical University. Frailty was measured by the 28‐item frailty index, and sarcopenia was assessed sarcopenia was assessed by skeletal muscle index in computed tomographic scan, handgrip strength and 6‐m walk. Participants were classified as follows: Group A: both sarcopenia and frailty; Group B: sarcopenia only; Group C: frailty only; and Group D: neither frailty nor sarcopenia. The primary outcome was 90‐day morbidity. Multivariable logistic regression model was used to estimate the association between sarcopenia, frailty and 90‐day morbidity.ResultsThe median (interquartile range) age of participants was 68 (64–72) years, and 62.7% were men. The prevalence rates of sarcopenia and frailty were 32.8% and 47.6%, respectively. The 90‐day morbidity in Group A was 58.5%, in Group B was 46.2%, in Group C was 42.0% and in Group D was 28.8%, and the difference was significant (P < 0.001). In the multivariable analysis, both sarcopenia and frailty [odds ratio (OR), 2.21; 95% confidence interval (CI), 1.26–3.89], sarcopenia only (OR, 1.84; 95% CI, 1.01–3.36), frailty only (OR, 1.77; 95% CI, 1.03–3.03), women (OR, 0.67; 95% CI, 0.45–0.99), body mass index (OR, 0.94; 95% CI, 0.88–0.99), pre‐operative albumin (OR, 0.96; 95% CI, 0.91–1.00) and operative stress score (OSS) [OSS 3 (OR, 2.09; 95% CI, 1.21–3.67); OSS 4–5 (OR, 3.81; 95% CI, 2.31–6.42)] were independently associated with 90‐day morbidity. In the multivariable analysis with inverse probability weighting adjusted cohort, sarcopenia and frailty were also significantly associated with 90‐day morbidity.ConclusionsSarcopenia and frailty were associated with higher risks of postoperative 90‐day morbidity in elderly patients alone and in combination. Sex, body mass index, pre‐operative albumin and operative stress were also independent factors for postoperative morbidity within 90 days.

show abstract

Comparison of Two Malnutrition Assessment Scales in Predicting Postoperative Complications in Elderly Patients Undergoing Noncardiac Surgery

Cited by 8 publications

References 30 publications

A preoperative prediction model based on Lymphocyte-C-reactive protein ratio predicts postoperative anastomotic leakage in patients with colorectal carcinoma: a retrospective study

A preoperative prediction model based on Lymphocyte-C-reactive protein ratio predicts postoperative anastomotic leakage in patients with colorectal carcinoma: a retrospective study

Relationship between Mini Nutritional Assessment Score and Infection in Critical Care Patients

Effects of sarcopenia and frailty on postoperative recovery in elderly patients: A prospective cohort study

Contact Info

Product

Resources

About