A systematic review was carried out to examine measurement tools of therapeutic relational communication, using an electronic search of the following databases: PubMed, LILACS, CINAHL, CiberIndex, Scielo and Scopus. The project followed the guidelines of Preferred Reporting Items for Systematic Reviews and Meta-Analysis and the protocol recommended by the Consensus-based Standards for the selection of health Measurement Instruments (COSMIN) panel. Thirteen instruments were included in the review. and their measurement properties were tested. The most common communication elements found in the measuring instruments were: empathy, respect, listening, contact, communicative competence, communication quality, and communication skills. Studies that used a theoretical foundation were based on patient-centered humanistic models. Empathy, respect, controlled contact, and other basic elements of interpersonal communication were most commonly found among the measuring regents. In conclusion, this review analyzed the theoretical foundations of the components of instruments used to measure therapeutic relational communication in the nursing field.