“…Female never smokers 9 0.76 (0.64-0.89) <0.1 0.61 [28,29,32,39,44,47,52,53,62] Female ever smokers 3 0.91 (0.69-1.19) 54.5 0.07 [32,39,52] Geographical region Asia 8 0.76 (0.66-0.88) 29.2 0.18 [28,29,43,44,46,52,58,62] United States/Canada 10 0.82 (0.73-0.92) 46.6 0.03 [31,32,34,36,39,41,53,56,59,60] Europe 9 0.83 (0.66-1.04) 71.6 <0.001 [35,38,[47][48][49]54,57,61,107] GST genotype GSTM1 null 8 0.73 (0.53-1.01) 70.5 0.001 [33,42,50,51,[55][56][57]59] GSTM1 present 8 0.76 (0.64-0.90) <0.1 0.45 [33,42,…”