Competitive Gut Exclusion of Avian Pathogens by Lactobacillus acidophilus in Gnotobiotic Chicks

Watkins, Bruce A.; Miller, B. F.

doi:10.3382/ps.0621772

Cited by 73 publications

(36 citation statements)

References 14 publications

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“…However, this practice is not effective for the practical control of fowl typhoid (Silva et al, 1981). It is effective to use competitive exclusion products which either derived from a suspension or anaerobic cultures of gut contents of healthy adult birds as a prophylactic treatment rather than as therapeutic agents (Watkins and Miller, 1983).…”

Section: The Competitive Exclusion Role Of Git Commensal Microorganismentioning

confidence: 99%

The role of the commensal gut microbial community in broiler chickens

Verstegen

Tamminga

et al. 2005

World's Poultry Science Journal

239

162

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To understand the relationship between the gastrointestinal inhabiting microbial community and broiler health, a literature review is presented. The available information on the development of gut microbial community, the relationship between commensal microflora and digestive function, the role of gut microorganisms on competitive exclusion of chickens against pathogens, and modulation of the gut microbial community by addition of prebiotics to the diet is summarized. Gut dominant microbial communities become more complex as broilers grow older. The establishment of the dominant bacterial community is affected by dietary and host-related factors. Dietary prebiotics can modulate bacterial community shift towards non-harmful bacteria, which is beneficial for the health of broiler chickens. Gut commensal microorganisms play an important role in the prevention of colonization by pathogens in the gastrointestinal tract of chickens, a process known as competitive exclusion. In conclusion, the dilemma caused by the forthcoming ban of antibiotics feed additives and need to maintain the intestinal health of broiler chickens, has produced an enormous interest in finding alternatives. Modulating the intestinal microbial community in a healthy direction, by dietary ingredients such as prebiotics, could be a good solution.

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Section: The Competitive Exclusion Role Of Git Commensal Microorganismentioning

confidence: 99%

The role of the commensal gut microbial community in broiler chickens

Verstegen

Tamminga

et al. 2005

World's Poultry Science Journal

239

162

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“…Watkins & Miller (1983) have compared the efficiency of single and continuous administration of L. acidophilus on shedding of S. typhimurium in chickens. The viable counts of salmonellae in the feces were significantly lower (p < 0.01) during the continuous application in comparison with single application.…”

Section: Discussionmentioning

confidence: 99%

Effect of Lactobacillus fermentum alone, and in combination with zinc(II) propionate on Salmonella enterica serovar Düsseldorf in Japanese quails

et al. 2006

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The influence of zinc(II) propionate on the efficacy of Lactobacillus fermentum against Salmonella enterica serovar Düsseldorf was tested in Japanese quails. Twenty one 3-day old Japanese quails were divided into 3 groups each consisting of 7 birds and inoculated orally: (i) group A (control) with Rogosa broth; (ii) group B with rifampicin-resistant L. fermentum (2.5 × 10 7 CFU/animal); and (iii) group C with rifampicin-resistant L. fermentum cultured in Rogosa broth supplemented with zinc(II) propionate (1 g Zn 2+ /L of broth; i.e. 2.5 × 10 7 CFU/animal and 0.1 mg Zn 2+ /animal). After 16 hours all birds were infected with a single dose of S. enterica serovar Düsseldorf (5.8 × 10 7 CFU/animal). During the next 6 days the chicks received the same inoculations as they had received earlier through the medium of drinking water. The viable counts of Salmonella, rifampicin-resistant lactobacilli and total aerobes in the feces and cecal content, zinc concentration in the cecal content and growth performance were evaluated. L. fermentum alone, and in combination with Zn(II) propionate significantly reduced shedding of Salmonella in the feces and also the amount of salmonellae present in cecal content as compared to control. The numbers of Salmonella in group C in all collections were lower than in group B, but a significant difference (p < 0.05) was noted only 24 h after infection. The viable counts of rifampicin-resistant lactobacilli were similar in groups B and C and numbers of total aerobes were reduced in these groups compared with control. L. fermentum and its combination with zinc(II) propionate increased daily weight gains in the chicks in comparison with control. Zinc concentration in the control and C group was 34.9 ± 6.2 mg · kg −1 and 676.3 ± 106.6 mg · kg −1 of cecal content, respectively.

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“…Lactobacilli are grown by using carbohydrates, and produce lactic acid. Lactic acid is used as substrate by other organisms and inhibits growth of the pathogens (Chomakov and Boicheva 1988, Tannock 1990, Watkins and Miller 1983.…”

Section: Discussionmentioning

confidence: 99%

Deterination of Some Properties of Lactobacillus Strains Isolated from Cecum

Karahan¹,

Çakmakçı²

1998

Tarım Bilimleri Dergisi

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: T Some properties o antibacterial activit and proteolytic acti less lactic acid tha levels. It was foun Lactobacillus strai tal number of 36 Lactobacillus strains were isolated and identified from cecum in our previous study. those strains were determined, These properties were lactic acid production, proteolytic activity and against pathogens. It was determined that lactic acid productions ranged from 2.200 to 6,800 mg/ml, ity ranged between 0.013 and 8.600 mg tyrosine/5 ml. Strains with high proteolytic activity produced the others. Beyond that 25 strains inhibited E. coli K12 107 and S. typhimurium 60-62 at different that S. typhimurium 60-62 was inhibited more than was E. coli K12 107, and the most effective s were L. fermentum KY2002 and L. plantarum KY2402.

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Competitive Gut Exclusion of Avian Pathogens by Lactobacillus acidophilus in Gnotobiotic Chicks

Cited by 73 publications

References 14 publications

The role of the commensal gut microbial community in broiler chickens

The role of the commensal gut microbial community in broiler chickens

Effect of Lactobacillus fermentum alone, and in combination with zinc(II) propionate on Salmonella enterica serovar Düsseldorf in Japanese quails

Deterination of Some Properties of Lactobacillus Strains Isolated from Cecum

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