Compilation of Secondary Metabolites from Bidens pilosa L.

Silva, Fabiana Lima; Fischer, Dominique Corinne Hermine; Tavares, Josean Fechine; Silva, Marcelo Sobral; Athayde-Filho, Petrônio Filgueiras de; Barbosa-Filho, José Maria

doi:10.3390/molecules16021070

Cited by 112 publications

(60 citation statements)

References 97 publications

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“…Around 116 publications have documented the exploitation and medical use of B. pilosa . To date, 201 compounds comprising 70 aliphatics, 60 flavonoids, 25 terpenoids, 19 phenylpropanoids, 13 aromatics, 8 porphyrins, and 6 other compounds, have been identified from this plant as compiled previously [27]. The structures of these compounds are presented in Tables 4, 5, 6, 7, 8, 9, and 10, respectively.…”

Section: Phytochemicalsmentioning

confidence: 97%

Bidens pilosaL. (Asteraceae): Botanical Properties, Traditional Uses, Phytochemistry, and Pharmacology

Bartolome

Villaseñor

Yang

2013

Evidence-Based Complementary and Alternative Medicine

217

220

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There are 230 to 240 known Bidens species. Among them, Bidens pilosa is a representative perennial herb, globally distributed across temperate and tropical regions. B. pilosa has been traditionally used in foods and medicines without obvious adverse effects. Despite significant progress in phytochemical and biological analyses of B. pilosa over the past few years, comprehensive and critical reviews of this plant are anachronistic or relatively limited in scope. The present review aims to summarize up-to-date information on the phytochemistry, pharmacology, and toxicology of B. pilosa from the literature. In addition to botanical studies and records of the traditional use of B. pilosa in over 40 diseases, scientific studies investigating the potential medicinal uses of this species and its constituent phytochemicals for a variety of disorders are presented and discussed. The structure, bioactivity, and likely mechanisms of action of B. pilosa and its phytochemicals are emphasized. Although some progress has been made, further rigorous efforts are required to investigate the individual compounds isolated from B. pilosa to understand and validate its traditional uses and develop clinical applications. The present review provides preliminary information and gives guidance for further basic and clinical research into this plant.

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Section: Phytochemicalsmentioning

confidence: 97%

Bidens pilosaL. (Asteraceae): Botanical Properties, Traditional Uses, Phytochemistry, and Pharmacology

Bartolome

Villaseñor

Yang

2013

Evidence-Based Complementary and Alternative Medicine

217

220

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“…Our group has also reviewed both poisonous and medicinal plants in Northeastern Brazil [33,34], among others [35–54]. …”

Section: Introductionmentioning

confidence: 99%

Tannins, Peptic Ulcers and Related Mechanisms

Jesus

Falcão

Gomes

et al. 2012

IJMS

Self Cite

143

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This review of the current literature aims to study correlations between the chemical structure and gastric anti-ulcer activity of tannins. Tannins are used in medicine primarily because of their astringent properties. These properties are due to the fact that tannins react with the tissue proteins with which they come into contact. In gastric ulcers, this tannin-protein complex layer protects the stomach by promoting greater resistance to chemical and mechanical injury or irritation. Moreover, in several experimental models of gastric ulcer, tannins have been shown to present antioxidant activity, promote tissue repair, exhibit anti Helicobacter pylori effects, and they are involved in gastrointestinal tract antiinflammatory processes. The presence of tannins explains the anti-ulcer effects of many natural products.

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“…The structural characterization of the above thiophene derivatives were studied by many research groups and are summarized in Table 1. (Marotti et al, 2010), (Takahashi et al, 2011), (Silva et al, 2011), ( Saha, Walia, Kundu, Kumar, & Joshi, 2012), ( Vijay, Laxman, Balasaheb, Yuvraj & Janardhan, 2013), ( Deineka, Tret'yakov, Lapshova, & Deineka, 2014) …”

Section: Introductionmentioning

confidence: 99%

One Step Synthesis of Polythiophenes from the Partially Purified Crude Extract of the Roots of Tagetes Erecta

Kodithuwakku

Alwis²,

Prashantha³

et al. 2016

IJC

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Polythiophene and its derivatives are valuable conjugated polymers due to their physical properties and applications in various fields. Precursors of polythiophenes were conventionally obtained from petrochemical byproducts, which are non-renewable. Thiophene and its derivatives had been found naturally in Tagetes species such as Tagetes erecta, Tagetes tenuifolia, etc. Tagetes species produce 2, 2':5', 2''-terthienyl (Alpha-T), 5-(3-buten-1-ynyl)-2, 20-bithienyl (BBT), 5-(4-hydroxy-1-butynyl)-2, 20-bithienyl (BBTOH), and 5-(4-acetoxy-1-butynyl)-2, 20-bithienyl (BBTOAc), which are accumulated in different parts, specifically in the roots of the plants. These thiophene derivatives were extracted and identified by GC-MS, Uv-vis, FTIR and TLC analysis. The partially purified plant extract is polymerized through one step oxidative free radical polymerization to obtain polythiophenes. Product characterization has revealed that the selective polymerization of thiophene derivatives results in the phase-separated end product from the rest of the materials in the plant-extract.

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Compilation of Secondary Metabolites from Bidens pilosa L.

Cited by 112 publications

References 97 publications

Bidens pilosaL. (Asteraceae): Botanical Properties, Traditional Uses, Phytochemistry, and Pharmacology

Bidens pilosaL. (Asteraceae): Botanical Properties, Traditional Uses, Phytochemistry, and Pharmacology

Tannins, Peptic Ulcers and Related Mechanisms

One Step Synthesis of Polythiophenes from the Partially Purified Crude Extract of the Roots of Tagetes Erecta

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