“…117,118 Interestingly some other diseases not thought to be complement mediated are being linked to alternative pathway mutations or were found to inexplicably be complement responsive. This includes IgA nephropathy, 80,98 idiopathic nonischemic cardiomyopathy, 120 myasthenia gravis, 121 and age-related macular degeneration. 122 For a graphical depiction of the differential TMA syndromes and their rough relationship to each other according to current data, see Figure 2.…”