IntroductionTorsion of gallbladder is an uncommon cause of acute abdomen. Volvulus occurs along the long axis of the gallbladder mesentery, and according to the degree of rotation symptoms, and signs may vary.Case presentationA 79-year-old woman presented with a one-day history of acute onset of right upper abdominal pain. The patient underwent laparotomy with a preoperative diagnosis of acalculous cholecystitis with possible gangrene. At laparotomy, the gallbladder was distended, and multiple necrotic areas were observed. It was rotated more than 180 degrees clockwise around the mesentery, and cholecystectomy was performed.ConclusionCholecystectomy is the treatment of gallbladder torsion. Clinical signs and radiographic studies may be helpful to diagnose gallbladder torsion. Early diagnosis and surgical treatment lower the mortality of disease.