The objective of this study was to analyse non-fatal suicidal self-poisonings in children and adolescents and to identify commonalities that might direct preventive health efforts. From the database of the Czech Toxicological Information Center, the inquiries due to non-fatal suicidal self-poisonings in children (9-13 years old) and adolescents (14-18 years old) in 2007-2011 were evaluated. From 10,492 calls about suicide attempts, 2393 concerned children and adolescents (13.5% and 86.5%, respectively). Most suicide attempts were committed during the spring (31.3%). Among toxic agents, drugs were used in 97.8% of the cases. 63% of cases involved monopoisonings and combinations of more than three drugs (10.3%) were rare. The most frequent ingestions appeared using drugs affecting the nervous system and anti-inflammatory non-steroids. The dose was evaluated as toxic in 73.4% of the cases and as severely toxic in 3.0% of the cases. The symptoms of moderate and severe intoxications were present in 10.5% of the cases. First aid was provided in 5.6%, and gastric lavage was performed in 21.9% of the cases. Antidotes were indicated in 13.3% and secondary elimination methods in 4.4% of the cases. Mostly, one or two easily accessible drugs were used in suicide attempts, with paracetamol and ibuprofen were the most common ones. Only one in 10 children applied a non-toxic dose. One-fifth of the patients received medical care within 60 min. and one-third later than 4 hr after exposure. The time criterion for gastric lavages was fulfilled in less than half of the cases, and in every fourth case, the procedure was performed when it was unlikely to be beneficial.The problem of suicides in children and adolescents as one of the leading causes of death is widely discussed [1][2][3][4][5]. Suicide is the fifth among the leading factors of death for children between 9 and 13 years of age and the third for adolescents between 14 and 18 years of age in the USA [6]. In Europe, suicide is the second leading cause of death in male and female adolescents [7,8].For young people, non-fatal suicidal behaviour is more prevalent than completed suicides, so the ratio of completed suicides to non-fatal suicide attempts may reach 1:10-20 [9,10]. However, those who survive suicidal attempts may often harm themselves seriously and suffer from the health consequences requiring long-term medical assistance [11]. Poisoning is the most common method of non-fatal suicide attempt all around the world [12][13][14][15]. A certain deficit of information on nonfatal suicidal behaviour exists; the main reason lies in the difficulty of collecting reliable information [14,16]. Hence, the scale of attempted suicide is not clearly known; the large part of cases remains unnoticed. Therefore, their circumstances important for morbidity and mortality prevention have not been sufficiently investigated [17][18][19].Poison control centres collect data on calls concerning suicide attempts lacking in national mortality registries by keeping the records of cons...